Skip to main content
SpringerLink
Log in
Book cover

Disorders of the Neonatal Airway pp 25–34Cite as

Disorders of the Midface

  • Chapter
  • First Online:

  • 1819 Accesses

Abstract

A patent nasal airway is crucial for normal neonatal respiration. Any functional or anatomic obstruction can lead to significant respiratory distress necessitating immediate intervention. This chapter presents an overview of conditions causing neonatal airway obstruction, focusing on syndromes causing midfacial narrowing and nasal obstructive lesions. A brief overview of the embryologic development of the midface, and important general history and physical exam findings are also included for completeness. Discussion of pyriform aperture stenosis and choanal atresia will be covered in the following chapter.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Robin NH, Falk MJ, Haldeman-Englert CR. FGFR-related craniosynostosis syndromes. Gene Reviews. (http://www.ncbi.nlm.nih.gov/books/NBK1455/). 2011.

  2. Brown L, Proctor MR. Endoscopically assisted correction of sagittal craniosynostosis. AORN J. 2011;93:566–79.

    Article  PubMed  Google Scholar 

  3. Agochukwu NB, Solomon BD. Impact of genetics on the diagnosis and clinical management of syndromic craniosynostoses. Childs Nerv Syst. 2012;28:1447–63.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Forrest CR, Hopper RA. Craniofacial syndromes and surgery. Plast Reconstr Surg. 2013;131(1):86–109.

    Article  Google Scholar 

  5. Cohen MM. Apert syndrome, not Apert’s syndrome: Apert neither had nor owned the syndrome that bears his name. Plast Reconstr Surg. 1997;100:532–3.

    PubMed  Google Scholar 

  6. Lee DS, Chung KC. Eugene Apert and his contributions to plastic surgery. Ann Plast Surg. 2010;64:362–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Heuze Y, Singh N, Basilico C, Jabs EW, Holmes G, Rictsmeier JT. Morphological comparison of the craniofacial phenotypes of mouse models expressing the Apert FGFR2 S252W mutation in neural crest-or mesoderm-derived tissues. Bone. 2014;63:101–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Bhatia PV, Patel PS, Jani UV, Soni NC. Apert’s syndrome: report of a rare case. J Oral Maxillofac Pathol. 2013;17:294–7.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Perlyn CA, Nichols C, Woo A, Becker D, Kane AA. Le premier siècle: one hundred years of progress in the treatment of Apert syndrome. J Craniofac Surg. 2009;20:801–6.

    Article  PubMed  Google Scholar 

  10. Pfeiffer RA. [Dominant hereditary acrocephalosyndactylia]. Z Kinderheilkd. 1964;90:301–20.

    Article  CAS  PubMed  Google Scholar 

  11. Muenke M, Schell U, Hehr A, et al. A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer Syndrome. Nat Genet. 1994;8:269–74.

    Article  CAS  PubMed  Google Scholar 

  12. Rutland P, Pulleyn LJ, Reardon W, et al. Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes. Nat Genet. 1995;9:173–6.

    Article  CAS  PubMed  Google Scholar 

  13. Glaser RL, Jiang W, Boyadjiev SA, et al. Paternal origin of FGFR2 mutations in sporadic cases of Crouzon syndrome and Pfeiffer syndrome. Am J Hum Genet. 2000;66:768–77.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Fearon JA, Rhodes J. Pfeiffer syndrome: a treatment evaluation. Plast Reconstr Surg. 2009;123(5):1–9.

    Article  Google Scholar 

  15. Aina VH, et al. Pfeiffer syndrome: analysis of a clinical series and development of a classification system. J Craniofac Surg. 2013;24:204–15.

    Article  Google Scholar 

  16. Vogels A, Fryns JP. Pfeiffer syndrome. Orphanet J Rare Dis. 2006;1:19.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Mitsukawa N, Kaneko T, Saiga A, Akita S, Satoh K. Early midfacial distraction for syndromic craniosynostotic patients with obstructive sleep apnoea. J Plast Reconstr Aesthet Surg. 2013;66(9):1206–11.

    Article  PubMed  Google Scholar 

  18. Bhattacharjee A, Uddin S, Purkaystha P. Deviated nasal septum in the newborn-A 1 year study. Indian J Otolaryngol Head Neck Surg. 2005;57(4):p304–8.

    Google Scholar 

  19. Bevans S. Boseley MB. Neonatal septal hematoma. Poster presentation at Combined Otolaryngological Societies meeting, April 12–14 2012. San Diego, CA.

    Google Scholar 

  20. Hossain T, Kappelman MD, Perez-Atayde AR, Young GJ, Huttner KM, Christou H. Primary Ciliary Dyskinesia as a cause of neonatal respiratory distress: implications for the neonatologist. J Perinatol. 2003;23:684–7.

    Article  PubMed  Google Scholar 

  21. Emami AJ, Brodsky L, Pizzuto M. Neonatal septoplasty: case report and review of the literature. Int J Pediatr Otorhinolaryngol. 1996;35:271–5.

    Article  CAS  PubMed  Google Scholar 

  22. Healy G. An approach to the nasal septum in children. Laryngoscope. 1986;96:123991242.

    Google Scholar 

  23. Duval M, Alsaba BH, Carpineta L, Daniel SJ. Respiratory distress secondary to bilateral nasolacrimal duct mucoceles in a newborn. Otolaryngol Head Neck Surg. 2007;137:353–4.

    Article  PubMed  Google Scholar 

  24. Herr M, Clarisse B, Nikasinovic L, Foucault C, Le Marec AM, Giordanella JP, Just J, Momas I. Does allergic rhinitis exist in infancy? Findings from the PARIS birth cohort. Allergy. 2011;66(2):214–21.

    Article  CAS  PubMed  Google Scholar 

  25. Nathan CO, Seid AB. Neonatal rhinitis. Int J Pediatr Otolaryngol. 1997;39:59–65.

    Article  CAS  Google Scholar 

  26. Jazbi B. Diagnosis and treatment of nasal birth deformities. Clin Pediatr (Phila). 1974;13:1974.

    Article  Google Scholar 

  27. Sooknundan M, Deka RC, Kacker SK, Verma IC. Indian J Pediatr. 1986;53:105–8.

    Article  Google Scholar 

  28. Schafer AT, Lembe R, AIthoff H. Airway resistance of posterior nasal pathway in sudden infant death victims. Eur J Pediatr. 1991;150(595):598.

    Google Scholar 

  29. Friedman NR, Luck M, Scapa VI. Excision of congenital nasolacrimal duct cyst with powered instrumentation. Laryngoscope. 2011;121:135–6.

    Article  PubMed  Google Scholar 

  30. Jacobs AH. Strawberry hemangiomas: the natural history of the untreated lesion. Calif Med. 1957;86:8–10.

    CAS  PubMed  PubMed Central  Google Scholar 

  31. Drolet BA, Esterly NB, Frieden IJ. Hemangiomas in children. N Engl J Med. 1999;341:173–81.

    Article  CAS  PubMed  Google Scholar 

  32. Warner NM, et al. The nonrandom distribution of facial hemangiomas. Arch Dermatol. 2003;139(7):869–75.

    Google Scholar 

  33. Sommers Smith SK, Smith DK. Beta blockade induces apoptosis in cultured capillary endothelial cells. In Vitro Cell Dev Biol Anim. 2002;38(5):298–304.

    Article  CAS  PubMed  Google Scholar 

  34. Storch CH, Hoeger PH. Propranolol for infantile hemangiomas: insights into molecular mechanisms of action. Br J Dermatol. 2010;163(2):269–74.

    Article  CAS  PubMed  Google Scholar 

  35. Drolet BA, et al. Initiation and Use of propranolol for infantile hemangioma: report of a consensus conference. Pediatrics. 2013;181(1):128–40.

    Article  Google Scholar 

  36. Cay A, Bektas D, Imamoglu M, Bahadir O, Cobanoglu U, Sarihan H. Oral teratoma: a case report and literature review. Pediatr Surg Int. 2004;20:304–8.

    Article  PubMed  Google Scholar 

  37. Rybak LP, Rapp MF, McGrady MD, Schwart MR, Myers PW, Orvidas L. Obstructing nasopharyngeal teratoma in the neonate. A report of two cases. Arch Otolaryngol Head Neck Surg. 1991;117(12):1411–5.

    Article  CAS  PubMed  Google Scholar 

  38. Makki FM, Al-Mazrou KA. Nasopharyngeal teratoma associated with cleft palate in a newborn. Eur Arch Otorhinolaryngol. 2008;265(11):1413–5.

    Article  PubMed  Google Scholar 

  39. Chaudhry AP, Lore JM, Fisher JE, Gambrino AG. So-called hairy polyps or teratoid tumors of the nasopharynx. Arch Otolaryngol. 1978;104:517–25.

    Article  CAS  PubMed  Google Scholar 

  40. Coppit GL, Perkins JA, Manning SC. Nasopharyngeal teratomas and dermoids: a review of the literature and case series. Int J Pediatr Otorhinolaryngol. 2000;52(3):219–27.

    Article  PubMed  Google Scholar 

  41. Kumar A, Helling E, Guenther D, et al. Correction of frontonasoethmoidal encephalocele: the HULA procedure. Plast Reconstr Surg. 2009;132(2):661–9.

    Article  Google Scholar 

  42. Holm C, Thu M, et al. Extracranial correction of frontoethmoidal meningoencephaloceles: feasibility and outcomes in 52 consecutive cases. Plast Reconstr Surg. 2008;121(6):386–95.

    Article  Google Scholar 

  43. Kanev PM. Congenital malformations of the skull and meninges. Otolarynol Clin North Am. 2007;40(1):9–26.

    Article  Google Scholar 

  44. Andrews BT, Meara JG. Reconstruction of frontoethmoidal encephalocele defects. Atlas Oral Maxillofac Surg Clin North Am. 2010;18(2):129–38.

    Article  PubMed  Google Scholar 

  45. Suwanwela C, Suwanwela N. A morphological classification of sincipital encephalomeningoceles. J Neurosurg. 1972;36:201–11.

    Article  CAS  PubMed  Google Scholar 

  46. Kilcline C, Frieden IJ. Infantile hemangiomas: how common are they? A systematic review of the medical literature. Pediatr Dermatol. 2008;25(2):168–73.

    Google Scholar 

  47. Saettele M, Alexander A, Markovich B, Morelli J, Lowe LH. Congenital midline nasofrontal masses. Pediatr Radiol. 2012;42(9):1119–25.

    Google Scholar 

  48. Swift AC, Singh SD. The presentation and management of the nasal glioma. Int J Pediatr Otorhinolaryngol. 1985;10(3):253–61.

    Google Scholar 

  49. Zapata SJ, Kearns DB. Nasal dermoids. Curr Opin Otolaryngol Head Neck Surg. 2006;14(6):406–11.

    Google Scholar 

  50. Rahbar R, Shah P, Mulliken JB, Robson CD, Perez-Atayde AR, Proctor MR, Kenna MA, Scott MR, McGill TJ, Healy GB. The presentation and management of nasal dermoid: a 30-year experience. Arch Otolaryngol Head Neck Surg. 2003;129(4):464–71.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Otolaryngology—Head and Neck Surgery, Madigan Army Medical Center, Tacoma, WA, USA

    Jacqueline Anderson M.D. & Bryan Liming M.D.

  2. Department of Otolaryngology—Head and Neck Surgery, University of Washington, Seattle, WA, USA

    Sanjay R. Parikh M.D. F.A.C.S.

Authors
  1. Jacqueline Anderson M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Bryan Liming M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sanjay R. Parikh M.D. F.A.C.S.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sanjay R. Parikh M.D. F.A.C.S. .

Editor information

Editors and Affiliations

  1. Attending Neonatologist, Director Neonatal Outreach, Medical Director, Neonatal Airway Program, The Children’s Hospital of Philadelphia, Associate Professor of Clinical Pediatrics, Department of Neonatology, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

    Janet Lioy

  2. Attending Surgeon, Fellowship Director, Pediatric Otolaryngology, The Center for Pediatric Airway Disorders, The Children’s Hospital of Philadelphia, Associate Professor, Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

    Steven E. Sobol

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media New York

About this chapter

Cite this chapter

Anderson, J., Liming, B., Parikh, S.R. (2015). Disorders of the Midface. In: Lioy, J., Sobol, S. (eds) Disorders of the Neonatal Airway. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1610-8_3

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1610-8_3

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-1609-2

  • Online ISBN: 978-1-4939-1610-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation