Abstract
Quantitative spectroscopy has been scientifically investigated since the 1800s, but application of spectroscopic techniques in medical diagnosis is relatively recent. Light reflectance and autofluorescence spectroscopy in the kidney and prostate have undergone extensive preclinical evaluation over the past decade. Initial promising findings with regard to differentiation of malignant from benign tissues and in characterization of tissue response to ischemia among others have been reported in select preclinical studies. However, limitations of current spectroscopic equipment, in spectral data processing, and a dearth of in vivo studies of these techniques in appropriate experimental models have resulted in their restricted use to the experimental setting, pending further development and clinical evaluation.
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Olweny, E.O., Cadeddu, J.A. (2015). Light Reflectance Spectroscopy and Autofluorescence (Kidney and Prostate). In: Liao, J., Su, LM. (eds) Advances in Image-Guided Urologic Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1450-0_8
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DOI: https://doi.org/10.1007/978-1-4939-1450-0_8
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