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Cancer Bioinformatics pp 113–147Cite as

Elucidation of Cancer Drivers Through Comparative Omic Data Analyses

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Abstract

Past statistics suggest that one out of every two men and every three women in developed countries will develop cancer during his or her life time. Cancer accounts for 12.5 % of all disease-induced deaths and ranks number three behind cardiovascular diseases and infectious and parasitic diseases worldwide. Its ranking moves up to number two when only developed countries are surveyed. A central question to be addressed here is: What causes a cancer to initiate and develop?

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA

    Ying Xu & David Puett

  2. Department of Computer Science and Engineering, University of Nebraska, Lincoln, NE, USA

    Juan Cui

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Appendix

Appendix

Table 5.1 A list of datasets used in analysis of Fig. 5.2
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Table 5.2 A list of datasets used in analysis of Fig. 5.4
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Table 5.3 Gene expression data of different species under hypoxia and normoxia
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Table 5.4 A list of ATP-consuming house-keeping genes in human used for the study of Sect. 5.4
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Xu, Y., Cui, J., Puett, D. (2014). Elucidation of Cancer Drivers Through Comparative Omic Data Analyses. In: Cancer Bioinformatics. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1381-7_5

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