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Perinatal Programming of Neurodevelopment pp 425–441Cite as

Perinatal Programming Prevention Measures

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Part of the book series: Advances in Neurobiology ((NEUROBIOL,volume 10))

Abstract

Over the past 10 years, there has been outstanding scientific progress related to perinatal programming and its epigenetic effects in health, and we can anticipate this trend will continue in the near future. We need to make use and apply these achievements to human neurodevelopment via prevention interventions. Based on the concept of the interaction between genome and ambiome, this chapter proposes low-cost easy-implementation preventive strategies for maternal and infant health institutions.

Breastfeeding and human milk administration are the first preventive measures, as has been reviewed in the policy statement of the American Academy of Pediatrics. Another strategy is the Safe and Family-Centered Maternity Hospitals initiative that promotes and empowers the inclusion of the families and the respect for their rights, especially during pregnancy and birth. (This change of paradigm was approved and is recommended by both United Nations Children’s Fund, UNICEF, and Pan American Health Organization, PAHO.) Then, there is also an important emphasis given to the sacred hour—which highlights the impact of bonding, attachment, and breastfeeding during the first hour of life—the pain prevention and treatment in newborns, the control of the “new morbidity” represented by late preterm infants, and finally, the importance of avoiding intrauterine and extrauterine growth restriction. (However, there are not yet clear recommendations about nutritional interventions in order to diminish the potential metabolic syndrome consequence in the adult.)

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Abbreviations

AAP:

American Academy of Pediatric

ABM:

Academy of Breastfeeding Medicine

AHA:

American Heart Association

EUGR:

Extrauterine growth restriction

GE:

Gestational age

IVH:

Intraventricular hemorrhage

NICU:

Neonatal intensive care unit

NRP:

Neonatal Resuscitation Program

PAHO:

Pan American Health Organization

PN:

Preterm newborn

PVL:

Periventricular leukomalacia

SFCF:

Safe and Family Centered Maternity Hospital

SSC:

Skin-to-skin contact

WHO:

World Health Organization

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Authors and Affiliations

  1. Division Neonatology, Hospital Materno Infantil R. Sardá, Esteban De Luca 2151, Ciudad Autónoma de Buenos Aires, Argentina

    A. Miguel Larguía M.D., Néstor Alejandro Dinerstein M.D. & Constanza Soto Conti M.D.

  2. Mental Health Section, Hospital Materno Infantil R. Sardá, Esteban De Luca 2151, Ciudad Autónoma de Buenos Aires, Argentina

    María Aurelia González

Authors
  1. A. Miguel Larguía M.D.
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  2. María Aurelia González
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  3. Néstor Alejandro Dinerstein M.D.
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  4. Constanza Soto Conti M.D.
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Corresponding author

Correspondence to A. Miguel Larguía M.D. .

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Editors and Affiliations

  1. Facultad de Medicina Inst de Biologia Celular y Neurociecias, Universidad de Buenos Aires, Buenos Aires, Argentina

    Marta C. Antonelli

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Larguía, A., González, M., Dinerstein, N., Soto Conti, C. (2015). Perinatal Programming Prevention Measures. In: Antonelli, M. (eds) Perinatal Programming of Neurodevelopment. Advances in Neurobiology, vol 10. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1372-5_20

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