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Robotically Assisted Radical Cystectomy

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Minimally Invasive Urology

Abstract

Robotically assisted radical cystectomy (RARC) is an exciting application of the robotic surgical platform whose role in future surgery is still being determined. Open radical cystectomy (ORC) as currently practiced is an effective although underutilized and significantly morbid procedure, with complication rates exceeding 60 % when strictly reported. Many different outcomes have been reported regarding potential benefits and costs with the robotically assisted approach, but at this point two factors have been consistently shown: blood loss is lower, and OR times are longer for RARC as compared to ORC. In some centers, outcomes and length of stay appear to favor the robotic approach, but in other centers of excellence, no benefit has been demonstrated when compared with well-executed, high-volume open cystectomy. That said, we are aware of no recent series that shows RARC to result in inferior oncologic or quality-associated outcomes such as length of stay or complication rate when compared to ORC. Costs are largely associated with avoidance of complications; as familiarity grows and technique is refined, the benefits of lower blood loss and decreased fluid shifts may ultimately result in measurably better outcomes and lower overall cost.

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References

  1. Marshall VJ, Whitemore WF. A technique for the extension of radical surgery in the treatment of vesical cancer. Cancer. 1949;2:424.

    Article  PubMed  CAS  Google Scholar 

  2. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Shabsigh A, Korets R, Vora KC, et al. Defining early morbidity of radical cystectomy for patients with bladder cancer using a standardized reporting methodology. Eur Urol. 2009;55:164.

    Article  PubMed  Google Scholar 

  4. Lowrance WT, Rumohr JA, Chang SS, et al. Contemporary open radical cystectomy: analysis of perioperative outcomes. J Urol. 2008;179:1313.

    Article  PubMed  Google Scholar 

  5. de Badajoz Sánchez E, Gallego Perales JL, Reche Rosado A, et al. Laparoscopic cystectomy and ileal conduit: case report. J Endourol. 1995;9:59.

    Article  Google Scholar 

  6. Puppo P, Perachino M, Ricciotti G, et al. Laparoscopically assisted transvaginal radical cystectomy. Eur Urol. 1995;27:80.

    PubMed  CAS  Google Scholar 

  7. Gettman MT, Blute ML, Peschel R, et al. Current status of robotics in urologic laparoscopy. Eur Urol. 2003;43:106.

    Article  PubMed  Google Scholar 

  8. Kim SP, Shah ND, Karnes RJ, et al. The implications of hospital acquired adverse events on mortality, length of stay and costs for patients undergoing radical cystectomy for bladder cancer. J Urol. 2012;187:2011.

    Article  PubMed  Google Scholar 

  9. Smith A, Kurpad R, Lal A, et al. Cost analysis of robotic versus open radical cystectomy for bladder cancer. J Urol. 2010;183:505.

    Article  PubMed  Google Scholar 

  10. Herr H, Lee C, Chang S, et al. Standardization of radical cystectomy and pelvic lymph node dissection for bladder cancer: a collaborative group report. J Urol. 2004;171:1823.

    Article  PubMed  Google Scholar 

  11. Kamat AM, Dinney CP, Gee JR, et al. Micropapillary bladder cancer: a review of the University of Texas M. D. Anderson Cancer Center experience with 100 consecutive patients. Cancer. 2007;110:62.

    Article  PubMed  Google Scholar 

  12. Richards KA, Kader K, Pettus JA, et al. Does initial learning curve compromise outcomes for robot-assisted radical cystectomy? A critical evaluation of the first 60 cases while establishing a robotics program. J Endourol. 2011;25:1553.

    Article  PubMed  Google Scholar 

  13. Guru KA, Perlmutter AE, Butt ZM, et al. The learning curve for robot-assisted radical cystectomy. JSLS. 2009;13:509.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Hayn MH, Hussain A, Mansour AM, et al. The learning curve of robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol. 2010;58:197.

    Article  PubMed  Google Scholar 

  15. Butt ZM, Perlmutter AE, Piacente PM, et al. Impact of body mass index on robot-assisted radical cystectomy. JSLS. 2008;12:241.

    PubMed  PubMed Central  Google Scholar 

  16. Johar RS, Hayn MH, Stegemann AP, et al. Complications after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol. 2013;64:52.

    Article  PubMed  Google Scholar 

  17. Gadacz TR, Talamini MA. Traditional versus laparoscopic cholecystectomy. Am J Surg. 1991;161:336.

    Article  PubMed  CAS  Google Scholar 

  18. Lloyd G, Rashid H, Wu G. Complex pelvic surgery in the setting of prior ostomy. Kyoto: World Congress of Endourology; 2011.

    Google Scholar 

  19. Meeks JJ, Bellmunt J, Bochner BH, et al. A systematic review of neoadjuvant and adjuvant chemotherapy for muscle-invasive bladder cancer. Eur Urol. 2012;62:523.

    Article  PubMed  CAS  Google Scholar 

  20. Hollenbeck BK, Miller DC, Taub D, et al. Aggressive treatment for bladder cancer is associated with improved overall survival among patients 80 years old or older. Urology. 2004;64:292.

    Article  PubMed  Google Scholar 

  21. Knox ML, El-Galley R, Busby JE. Robotic versus open radical cystectomy: identification of patients who benefit from the robotic approach. J Endourol. 2013;27:40.

    Article  PubMed  Google Scholar 

  22. Kaffenberger SD, Keegan KA, Bansal NK, et al. Salvage robotic assisted laparoscopic radical prostatectomy: a single institution, 5-year experience. J Urol. 2013;189:507.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Chahal R, Sundaram SK, Iddenden R, et al. A study of the morbidity, mortality and long-term survival following radical cystectomy and radical radiotherapy in the treatment of invasive bladder cancer in Yorkshire. Eur Urol. 2003;43:246.

    Article  PubMed  CAS  Google Scholar 

  24. Eswara JR, Efstathiou JA, Heney NM, et al. Complications and long-term results of salvage cystectomy after failed bladder sparing therapy for muscle invasive bladder cancer. J Urol. 2012;187:463.

    Article  PubMed  Google Scholar 

  25. Eisenberg MS, Dorin RP, Bartsch G, et al. Early complications of cystectomy after high dose pelvic radiation. J Urol. 2010;184:2264.

    Article  PubMed  Google Scholar 

  26. Lee DJ, Rothberg MB, McKiernan JM, et al. Robot-assisted radical cystoprostatectomy in complex surgical patients: single institution report. Can J Urol. 2009;16:4664.

    PubMed  Google Scholar 

  27. Zebic N, Weinknecht S, Kroepfl D. Radical cystectomy in patients aged > or = 75 years: an updated review of patients treated with curative and palliative intent. BJU Int. 2005;95:1211.

    Article  PubMed  Google Scholar 

  28. Nogueira L, dos Reis RB, Machado RD, et al. Cutaneous ureterostomy with definitive ureteral stent as urinary diversion option in unfit patients after radical cystectomy. Acta Cir Bras. 2013;28 Suppl 1:43.

    Article  PubMed  Google Scholar 

  29. Karl A, Carroll PR, Gschwend JE, et al. The impact of lymphadenectomy and lymph node metastasis on the outcomes of radical cystectomy for bladder cancer. Eur Urol. 2009;55:826.

    Article  PubMed  Google Scholar 

  30. Buscarini M, Josephson DY, Stein JP. Lymphadenectomy in bladder cancer: a review. Urol Int. 2007;79:191.

    Article  PubMed  Google Scholar 

  31. Mills RD, Fleischmann A, Studer UE. Radical cystectomy with an extended pelvic lymphadenectomy: rationale and results. Surg Oncol Clin N Am. 2007;16:233.

    Article  PubMed  Google Scholar 

  32. Stein JP. The role of lymphadenectomy in patients undergoing radical cystectomy for bladder cancer. Curr Oncol Rep. 2007;9:213.

    Article  PubMed  Google Scholar 

  33. Youssef RF, Raj GV. Lymphadenectomy in management of invasive bladder cancer. Int J Surg Oncol. 2011; 2011: Article ID 758189.

    Google Scholar 

  34. Tilki D, Brausi M, Colombo R, et al. Lymphadenectomy for bladder cancer at the time of radical cystectomy. Eur Urol. 2013;64:266.

    Article  PubMed  Google Scholar 

  35. Keren Paz GE, Laudone VP, Bochner BH. Does minimally invasive surgery for radical cystectomy provide similar long-term cancer control as open radical surgery? Curr Opin Urol. 2013;23:449.

    Article  PubMed  Google Scholar 

  36. Davis JW, Gaston K, Anderson R, et al. Robot assisted extended pelvic lymphadenectomy at radical cystectomy: lymph node yield compared with second look open dissection. J Urol. 2011;185:79.

    Article  PubMed  Google Scholar 

  37. Thompson IM, Kappa SF, Morgan TM, et al. Blood loss associated with radical cystectomy: a prospective, randomized study comparing Impact LigaSure vs. stapling device. Urol Oncol. 2013;32:45.e11–5.

    Article  Google Scholar 

  38. Johnson D, Castle E, Pruthi RS, et al. Robotic intracorporeal urinary diversion: ileal conduit. J Endourol. 2012;26:1566.

    Article  PubMed  Google Scholar 

  39. Pruthi R, Nix J, McRackan D, et al. Robotic-assisted laparoscopic intracorporeal urinary diversion. Eur Urol. 2010;57:1013.

    Article  PubMed  Google Scholar 

  40. Collins J, Tyritzis S, Nyberg T, et al. Robot-assisted radical cystectomy: description of an evolved approach to radical cystectomy. Eur Urol. 2013;64:654.

    Article  PubMed  Google Scholar 

  41. Collins J, Wiklund P, Desai M, et al. Total intracorporeal robotic cystectomy: are we there yet? Curr Opin Urol. 2013;23:135.

    Article  PubMed  Google Scholar 

  42. Goh A, Gill I, Lee D, et al. Robotic intracorporeal orthotopic ileal neobladder: replicating open surgical principles. Eur Urol. 2012;62:891.

    Article  PubMed  Google Scholar 

  43. Hosseini A, Adding C, Nilsson A, et al. Robotic cystectomy: surgical technique. BJU Int. 2011;108:962.

    Article  PubMed  Google Scholar 

  44. Jonsson M, Adding L, Hosseini A, et al. Robot-assisted radical cystectomy with intracorporeal urinary diversion in patients with transitional cell carcinoma of the bladder. Eur Urol. 2011;60:1066.

    Article  PubMed  Google Scholar 

  45. Josephson D, Chen J, Chan K, et al. Robotic-assisted laparoscopic radical cystoprostatectomy and extracorporeal continent urinary diversion: highlight of surgical techniques and outcomes. Int J Med Robot. 2010;6:315.

    Article  PubMed  CAS  Google Scholar 

  46. Murphy D, Anderson P. Robotic radical cystectomy with intracorporeal neobladder: ready for prime time? Eur Urol. 2013;64(5):742–3.

    Article  PubMed  Google Scholar 

  47. Blute M, George A, Herati A, et al. Intracorporeal neobladder reconstruction: pressure-flow urodyamic studies in cadaveric orthotopic neobladders. BJU Int. 2012;109:434.

    Article  PubMed  Google Scholar 

  48. Kauffman EC, Ng CK, Lee MM, et al. Critical analysis of complications after robotic-assisted radical cystectomy with identification of preoperative and operative risk factors. BJU Int. 2010;105:520.

    Article  PubMed  Google Scholar 

  49. Ng CK, Kauffman EC, Lee MM, et al. A comparison of postoperative complications in open versus robotic cystectomy. Eur Urol. 2010;57:274.

    Article  PubMed  Google Scholar 

  50. Parekh DJ, Messer J, Fitzgerald J, et al. Perioperative outcomes and oncologic efficacy from a pilot prospective randomized clinical trial of open versus robotic assisted radical cystectomy. J Urol. 2013;189:474.

    Article  PubMed  Google Scholar 

  51. Konety BR, Allareddy V. Influence of post-cystectomy complications on cost and subsequent outcome. J Urol. 2007;177:280.

    Article  PubMed  Google Scholar 

  52. Kader AK, Richards KA, Krane LS, et al. Robot-assisted laparoscopic vs open radical cystectomy: comparison of complications and perioperative oncological outcomes in 200 patients. BJU Int. 2013;112:E290.

    Article  PubMed  Google Scholar 

  53. Laudone V, Silberstein J, Keren-Paz G, et al. Interim analysis of a prospective, randomized trial comparing robotic and open radical cystectomy. Presented at the American Urological Association Annual Meeting. San Diego, 2013.

    Google Scholar 

  54. Gondo T, Yoshioka K, Nakagami Y, et al. Robotic versus open radical cystectomy: prospective comparison of perioperative and pathologic outcomes in Japan. Jpn J Clin Oncol. 2012;42:625.

    Article  PubMed  Google Scholar 

  55. Nepple KG, Strope SA, Grubb RL, et al. Early oncologic outcomes of robotic vs. open radical cystectomy for urothelial cancer. Urol Oncol. 2013;31:894.

    Article  PubMed  PubMed Central  Google Scholar 

  56. Wang GJ, Barocas DA, Raman JD, et al. Robotic vs open radical cystectomy: prospective comparison of perioperative outcomes and pathological measures of early oncological efficacy. BJU Int. 2008;101:89.

    PubMed  Google Scholar 

  57. Styn NR, Montgomery JS, Wood DP, et al. Matched comparison of robotic-assisted and open radical cystectomy. Urology. 2012;79:1303.

    Article  PubMed  Google Scholar 

  58. Nix J, Smith A, Kurpad R, et al. Prospective randomized controlled trial of robotic versus open radical cystectomy for bladder cancer: perioperative and pathologic results. Eur Urol. 2010;57:196.

    Article  PubMed  Google Scholar 

  59. Galich A, Sterrett S, Nazemi T, et al. Comparative analysis of early perioperative outcomes following radical cystectomy by either the robotic or open method. JSLS. 2006;10:145.

    PubMed  PubMed Central  Google Scholar 

  60. Sung HH, Ahn JS, Seo SI, et al. A comparison of early complications between open and robot-assisted radical cystectomy. J Endourol. 2012;26:670.

    Article  PubMed  Google Scholar 

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Correspondence to Granville L. Lloyd MD .

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Lloyd, G.L., Abel, E.J., Downs, T.M. (2015). Robotically Assisted Radical Cystectomy. In: Best, S., Nakada, S. (eds) Minimally Invasive Urology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1317-6_7

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  • DOI: https://doi.org/10.1007/978-1-4939-1317-6_7

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