Abstract
Robotically assisted radical cystectomy (RARC) is an exciting application of the robotic surgical platform whose role in future surgery is still being determined. Open radical cystectomy (ORC) as currently practiced is an effective although underutilized and significantly morbid procedure, with complication rates exceeding 60 % when strictly reported. Many different outcomes have been reported regarding potential benefits and costs with the robotically assisted approach, but at this point two factors have been consistently shown: blood loss is lower, and OR times are longer for RARC as compared to ORC. In some centers, outcomes and length of stay appear to favor the robotic approach, but in other centers of excellence, no benefit has been demonstrated when compared with well-executed, high-volume open cystectomy. That said, we are aware of no recent series that shows RARC to result in inferior oncologic or quality-associated outcomes such as length of stay or complication rate when compared to ORC. Costs are largely associated with avoidance of complications; as familiarity grows and technique is refined, the benefits of lower blood loss and decreased fluid shifts may ultimately result in measurably better outcomes and lower overall cost.
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References
Marshall VJ, Whitemore WF. A technique for the extension of radical surgery in the treatment of vesical cancer. Cancer. 1949;2:424.
Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205.
Shabsigh A, Korets R, Vora KC, et al. Defining early morbidity of radical cystectomy for patients with bladder cancer using a standardized reporting methodology. Eur Urol. 2009;55:164.
Lowrance WT, Rumohr JA, Chang SS, et al. Contemporary open radical cystectomy: analysis of perioperative outcomes. J Urol. 2008;179:1313.
de Badajoz Sánchez E, Gallego Perales JL, Reche Rosado A, et al. Laparoscopic cystectomy and ileal conduit: case report. J Endourol. 1995;9:59.
Puppo P, Perachino M, Ricciotti G, et al. Laparoscopically assisted transvaginal radical cystectomy. Eur Urol. 1995;27:80.
Gettman MT, Blute ML, Peschel R, et al. Current status of robotics in urologic laparoscopy. Eur Urol. 2003;43:106.
Kim SP, Shah ND, Karnes RJ, et al. The implications of hospital acquired adverse events on mortality, length of stay and costs for patients undergoing radical cystectomy for bladder cancer. J Urol. 2012;187:2011.
Smith A, Kurpad R, Lal A, et al. Cost analysis of robotic versus open radical cystectomy for bladder cancer. J Urol. 2010;183:505.
Herr H, Lee C, Chang S, et al. Standardization of radical cystectomy and pelvic lymph node dissection for bladder cancer: a collaborative group report. J Urol. 2004;171:1823.
Kamat AM, Dinney CP, Gee JR, et al. Micropapillary bladder cancer: a review of the University of Texas M. D. Anderson Cancer Center experience with 100 consecutive patients. Cancer. 2007;110:62.
Richards KA, Kader K, Pettus JA, et al. Does initial learning curve compromise outcomes for robot-assisted radical cystectomy? A critical evaluation of the first 60 cases while establishing a robotics program. J Endourol. 2011;25:1553.
Guru KA, Perlmutter AE, Butt ZM, et al. The learning curve for robot-assisted radical cystectomy. JSLS. 2009;13:509.
Hayn MH, Hussain A, Mansour AM, et al. The learning curve of robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol. 2010;58:197.
Butt ZM, Perlmutter AE, Piacente PM, et al. Impact of body mass index on robot-assisted radical cystectomy. JSLS. 2008;12:241.
Johar RS, Hayn MH, Stegemann AP, et al. Complications after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol. 2013;64:52.
Gadacz TR, Talamini MA. Traditional versus laparoscopic cholecystectomy. Am J Surg. 1991;161:336.
Lloyd G, Rashid H, Wu G. Complex pelvic surgery in the setting of prior ostomy. Kyoto: World Congress of Endourology; 2011.
Meeks JJ, Bellmunt J, Bochner BH, et al. A systematic review of neoadjuvant and adjuvant chemotherapy for muscle-invasive bladder cancer. Eur Urol. 2012;62:523.
Hollenbeck BK, Miller DC, Taub D, et al. Aggressive treatment for bladder cancer is associated with improved overall survival among patients 80 years old or older. Urology. 2004;64:292.
Knox ML, El-Galley R, Busby JE. Robotic versus open radical cystectomy: identification of patients who benefit from the robotic approach. J Endourol. 2013;27:40.
Kaffenberger SD, Keegan KA, Bansal NK, et al. Salvage robotic assisted laparoscopic radical prostatectomy: a single institution, 5-year experience. J Urol. 2013;189:507.
Chahal R, Sundaram SK, Iddenden R, et al. A study of the morbidity, mortality and long-term survival following radical cystectomy and radical radiotherapy in the treatment of invasive bladder cancer in Yorkshire. Eur Urol. 2003;43:246.
Eswara JR, Efstathiou JA, Heney NM, et al. Complications and long-term results of salvage cystectomy after failed bladder sparing therapy for muscle invasive bladder cancer. J Urol. 2012;187:463.
Eisenberg MS, Dorin RP, Bartsch G, et al. Early complications of cystectomy after high dose pelvic radiation. J Urol. 2010;184:2264.
Lee DJ, Rothberg MB, McKiernan JM, et al. Robot-assisted radical cystoprostatectomy in complex surgical patients: single institution report. Can J Urol. 2009;16:4664.
Zebic N, Weinknecht S, Kroepfl D. Radical cystectomy in patients aged > or = 75 years: an updated review of patients treated with curative and palliative intent. BJU Int. 2005;95:1211.
Nogueira L, dos Reis RB, Machado RD, et al. Cutaneous ureterostomy with definitive ureteral stent as urinary diversion option in unfit patients after radical cystectomy. Acta Cir Bras. 2013;28 Suppl 1:43.
Karl A, Carroll PR, Gschwend JE, et al. The impact of lymphadenectomy and lymph node metastasis on the outcomes of radical cystectomy for bladder cancer. Eur Urol. 2009;55:826.
Buscarini M, Josephson DY, Stein JP. Lymphadenectomy in bladder cancer: a review. Urol Int. 2007;79:191.
Mills RD, Fleischmann A, Studer UE. Radical cystectomy with an extended pelvic lymphadenectomy: rationale and results. Surg Oncol Clin N Am. 2007;16:233.
Stein JP. The role of lymphadenectomy in patients undergoing radical cystectomy for bladder cancer. Curr Oncol Rep. 2007;9:213.
Youssef RF, Raj GV. Lymphadenectomy in management of invasive bladder cancer. Int J Surg Oncol. 2011; 2011: Article ID 758189.
Tilki D, Brausi M, Colombo R, et al. Lymphadenectomy for bladder cancer at the time of radical cystectomy. Eur Urol. 2013;64:266.
Keren Paz GE, Laudone VP, Bochner BH. Does minimally invasive surgery for radical cystectomy provide similar long-term cancer control as open radical surgery? Curr Opin Urol. 2013;23:449.
Davis JW, Gaston K, Anderson R, et al. Robot assisted extended pelvic lymphadenectomy at radical cystectomy: lymph node yield compared with second look open dissection. J Urol. 2011;185:79.
Thompson IM, Kappa SF, Morgan TM, et al. Blood loss associated with radical cystectomy: a prospective, randomized study comparing Impact LigaSure vs. stapling device. Urol Oncol. 2013;32:45.e11–5.
Johnson D, Castle E, Pruthi RS, et al. Robotic intracorporeal urinary diversion: ileal conduit. J Endourol. 2012;26:1566.
Pruthi R, Nix J, McRackan D, et al. Robotic-assisted laparoscopic intracorporeal urinary diversion. Eur Urol. 2010;57:1013.
Collins J, Tyritzis S, Nyberg T, et al. Robot-assisted radical cystectomy: description of an evolved approach to radical cystectomy. Eur Urol. 2013;64:654.
Collins J, Wiklund P, Desai M, et al. Total intracorporeal robotic cystectomy: are we there yet? Curr Opin Urol. 2013;23:135.
Goh A, Gill I, Lee D, et al. Robotic intracorporeal orthotopic ileal neobladder: replicating open surgical principles. Eur Urol. 2012;62:891.
Hosseini A, Adding C, Nilsson A, et al. Robotic cystectomy: surgical technique. BJU Int. 2011;108:962.
Jonsson M, Adding L, Hosseini A, et al. Robot-assisted radical cystectomy with intracorporeal urinary diversion in patients with transitional cell carcinoma of the bladder. Eur Urol. 2011;60:1066.
Josephson D, Chen J, Chan K, et al. Robotic-assisted laparoscopic radical cystoprostatectomy and extracorporeal continent urinary diversion: highlight of surgical techniques and outcomes. Int J Med Robot. 2010;6:315.
Murphy D, Anderson P. Robotic radical cystectomy with intracorporeal neobladder: ready for prime time? Eur Urol. 2013;64(5):742–3.
Blute M, George A, Herati A, et al. Intracorporeal neobladder reconstruction: pressure-flow urodyamic studies in cadaveric orthotopic neobladders. BJU Int. 2012;109:434.
Kauffman EC, Ng CK, Lee MM, et al. Critical analysis of complications after robotic-assisted radical cystectomy with identification of preoperative and operative risk factors. BJU Int. 2010;105:520.
Ng CK, Kauffman EC, Lee MM, et al. A comparison of postoperative complications in open versus robotic cystectomy. Eur Urol. 2010;57:274.
Parekh DJ, Messer J, Fitzgerald J, et al. Perioperative outcomes and oncologic efficacy from a pilot prospective randomized clinical trial of open versus robotic assisted radical cystectomy. J Urol. 2013;189:474.
Konety BR, Allareddy V. Influence of post-cystectomy complications on cost and subsequent outcome. J Urol. 2007;177:280.
Kader AK, Richards KA, Krane LS, et al. Robot-assisted laparoscopic vs open radical cystectomy: comparison of complications and perioperative oncological outcomes in 200 patients. BJU Int. 2013;112:E290.
Laudone V, Silberstein J, Keren-Paz G, et al. Interim analysis of a prospective, randomized trial comparing robotic and open radical cystectomy. Presented at the American Urological Association Annual Meeting. San Diego, 2013.
Gondo T, Yoshioka K, Nakagami Y, et al. Robotic versus open radical cystectomy: prospective comparison of perioperative and pathologic outcomes in Japan. Jpn J Clin Oncol. 2012;42:625.
Nepple KG, Strope SA, Grubb RL, et al. Early oncologic outcomes of robotic vs. open radical cystectomy for urothelial cancer. Urol Oncol. 2013;31:894.
Wang GJ, Barocas DA, Raman JD, et al. Robotic vs open radical cystectomy: prospective comparison of perioperative outcomes and pathological measures of early oncological efficacy. BJU Int. 2008;101:89.
Styn NR, Montgomery JS, Wood DP, et al. Matched comparison of robotic-assisted and open radical cystectomy. Urology. 2012;79:1303.
Nix J, Smith A, Kurpad R, et al. Prospective randomized controlled trial of robotic versus open radical cystectomy for bladder cancer: perioperative and pathologic results. Eur Urol. 2010;57:196.
Galich A, Sterrett S, Nazemi T, et al. Comparative analysis of early perioperative outcomes following radical cystectomy by either the robotic or open method. JSLS. 2006;10:145.
Sung HH, Ahn JS, Seo SI, et al. A comparison of early complications between open and robot-assisted radical cystectomy. J Endourol. 2012;26:670.
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Lloyd, G.L., Abel, E.J., Downs, T.M. (2015). Robotically Assisted Radical Cystectomy. In: Best, S., Nakada, S. (eds) Minimally Invasive Urology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1317-6_7
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DOI: https://doi.org/10.1007/978-1-4939-1317-6_7
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