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Trauma and Acute Kidney Injury

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Perioperative Kidney Injury

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Abstract

Advances in trauma and critical care have enabled patients with more severe injuries to survive the initial traumatic insult. However, these same patients are at risk for organ dysfunction and failure as they recover from their injuries. Acute kidney injury is an independent risk factor for mortality in this patient population, and prevention of renal dysfunction is crucial to improving outcomes. The cause of renal failure in these situations varies anatomically and physiologically. While direct urologic trauma can occur, it rarely results in renal failure. More frequently, intravascular volume loss and hypotension requiring aggressive resuscitation is the predominant risk factor for subsequent renal dysfunction. In addition, specific injury patterns such as crush, electrical, burn, and limb ischemia/reperfusion increase the propensity for renal failure. Early recognition of these entities and timely treatment of hemorrhagic shock, coagulopathy, acidosis, and rhabdomyolysis can minimize the risk of acute kidney injury in the trauma patient.

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Authors and Affiliations

  1. Department of Surgery, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH, 45267, USA

    Krishna P. Athota MD & Betty J. Tsuei MD

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  1. Krishna P. Athota MD
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  2. Betty J. Tsuei MD
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Correspondence to Betty J. Tsuei MD .

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Editors and Affiliations

  1. Division of Nephrology and Hypertension, University of Cincinnati, Cincinnati, Ohio, USA

    Charuhas V. Thakar

  2. Program of Applied Translational Research, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA

    Chirag R. Parikh

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Athota, K.P., Tsuei, B.J. (2015). Trauma and Acute Kidney Injury. In: Thakar, C., Parikh, C. (eds) Perioperative Kidney Injury. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1273-5_16

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  • DOI: https://doi.org/10.1007/978-1-4939-1273-5_16

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