Skip to main content
SpringerLink
Log in

Experimental Alternatives in Bariatric Surgery

  • Chapter
  • First Online:
The ASMBS Textbook of Bariatric Surgery

  • 2487 Accesses

Abstract

Bariatric surgery remains the most effective treatment for obesity and weight-related comorbidities. Surgical intervention is often underutilized for a multitude of reasons. Limitations may include side effects, insurance restrictions, and accessibility. Future direction should aim at developing therapies that are less invasive, safer, and potentially allow for greater acceptance and accessibility. Endoluminal bariatric therapies, neurohormonal modulation, and innovative surgical techniques will likely determine the future direction of bariatric surgery. Emerging techniques should focus on offering more options for earlier management of obesity, as well as an alternative in advanced and recurrent disease. In order to achieve this goal, new procedures should offer a safer and less invasive profile than what is currently accepted.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Lee SM, Pryor AD. Future directions in bariatric surgery. Surg Clin North Am. 2011;91(6):1373–95, x [Review].

    Article  PubMed  Google Scholar 

  2. Sturm R. Increases in clinically severe obesity in the United States, 1986–2000. Arch Intern Med. 2003;163(18):2146–8.

    Article  PubMed  Google Scholar 

  3. Eldar S, Heneghan HM, Brethauer SA, Schauer PR. Bariatric surgery for treatment of obesity. Int J Obes (Lond). 2011;35 Suppl 3:S16–21 [Research Support, Non-U.S. Gov’t Review].

    Article  Google Scholar 

  4. Yimcharoen P, Heneghan HM, Tariq N, Brethauer SA, Kroh M, Chand B. Endoscopic stent management of leaks and anastomotic strictures after foregut surgery. Surg Obes Relat Dis. 2011;7(5): 628–36.

    Article  PubMed  Google Scholar 

  5. Levitzky BE, Wassef WY. Endoscopic management in the bariatric surgical patient. Curr Opin Gastroenterol. 2010;26(6):632–9 [Review].

    Article  PubMed  Google Scholar 

  6. Ginsberg GG, Chand B, Cote GA, Dallal RM, Edmundowicz SA, Nguyen NT, et al. A pathway to endoscopic bariatric therapies. Gastrointest Endosc. 2011;74(5):943–53.

    Article  PubMed  Google Scholar 

  7. O’Brien PE, Dixon JB, Laurie C, Skinner S, Proietto J, McNeil J, et al. Treatment of mild to moderate obesity with laparoscopic adjustable gastric banding or an intensive medical program: a randomized trial. Ann Intern Med. 2006;144(9):625–33 [Comparative Study Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov’t].

    Article  PubMed  Google Scholar 

  8. Kakoulidis TP, Karringer A, Gloaguen T, Arvidsson D. Initial results with sleeve gastrectomy for patients with class i obesity (bmi 30–35 kg/m2). Surg Obes Relat Dis. 2009;5(4):425–8 [Clinical Trial].

    Article  PubMed  Google Scholar 

  9. Gupta PK, Franck C, Miller WJ, Gupta H, Forse RA. Development and validation of a bariatric surgery morbidity risk calculator using the prospective, multicenter nsqip dataset. J Am Coll Surg. 2011;212(3):301–9 [Validation Studies].

    Article  PubMed  Google Scholar 

  10. Wagner BD, Grunwald GK, Rumsfeld JS, Hill JO, Ho PM, Wyatt HR, et al. Relationship of body mass index with outcomes after coronary artery bypass graft surgery. Ann Thorac Surg. 2007;84(1):10–6 [Research Support, U.S. Gov’t, Non-P.H.S.].

    Article  PubMed  Google Scholar 

  11. Fernandez Jr AZ, Demaria EJ, Tichansky DS, Kellum JM, Wolfe LG, Meador J, et al. Multivariate analysis of risk factors for death following gastric bypass for treatment of morbid obesity. Ann Surg. 2004;239(5):698–702; discussion 702–3.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Poobalan AS, Aucott LS, Smith WC, Avenell A, Jung R, Broom J. Long-term weight loss effects on all cause mortality in overweight/obese populations. Obes Rev. 2007;8(6):503–13 [Research Support, Non-U.S. Gov’t Review].

    Article  PubMed  CAS  Google Scholar 

  13. Ryou M, Ryan MB, Thompson CC. Current status of endoluminal bariatric procedures for primary and revision indications. Gastrointest Endosc Clin N Am. 2011;21(2):315–33 [Research Support, Non-U.S. Gov’t Review].

    Article  PubMed  PubMed Central  Google Scholar 

  14. Mahmood Z, McMahon BP, Arfin Q, Byrne PJ, Reynolds JV, Murphy EM, et al. Endocinch therapy for gastro-oesophageal reflux disease: a one year prospective follow up. Gut. 2003;52(1):34–9 [Evaluation Studies Research Support, Non-U.S. Gov’t].

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  15. Fogel R, De Fogel J, Bonilla Y, De La Fuente R. Clinical experience of transoral suturing for an endoluminal vertical gastroplasty: 1-year follow-up in 64 patients. Gastrointest Endosc. 2008;68(1):51–8 [Clinical Trial].

    Article  PubMed  Google Scholar 

  16. Brethauer SA, Chand B, Schauer PR, Thompson CC. Transoral gastric volume reduction for weight management: technique and feasibility in 18 patients. Surg Obes Relat Dis. 2010;6(6):689–94 [Clinical Trial Multicenter Study Research Support, Non-U.S. Gov’t Video-Audio Media].

    Article  PubMed  Google Scholar 

  17. Brethauer SA, Chand B, Schauer PR, Thompson CC. Transoral gastric volume reduction as intervention for weight management: 12-month follow-up of trim trial. Surg Obes Relat Dis. 2012;8(3): 296–303.

    Article  PubMed  Google Scholar 

  18. Deviere J, Ojeda Valdes G, Cuevas Herrera L, Closset J, Le Moine O, Eisendrath P, et al. Safety, feasibility and weight loss after transoral gastroplasty: first human multicenter study. Surg Endosc. 2008;22(3):589–98 [Controlled Clinical Trial Multicenter Study].

    Article  PubMed  CAS  Google Scholar 

  19. Moreno C, Closset J, Dugardeyn S, Barea M, Mehdi A, Collignon L, et al. Transoral gastroplasty is safe, feasible, and induces significant weight loss in morbidly obese patients: results of the second human pilot study. Endoscopy. 2008;40(5):406–13 [Controlled Clinical Trial Research Support, Non-U.S. Gov’t].

    Article  PubMed  CAS  Google Scholar 

  20. Herron DM, Birkett DH, Thompson CC, Bessler M, Swanstrom LL. Gastric bypass pouch and stoma reduction using a transoral endoscopic anchor placement system: a feasibility study. Surg Endosc. 2008;22(4):1093–9.

    Article  PubMed  Google Scholar 

  21. Benjamin SB, Maher KA, Cattau Jr EL, Collen MJ, Fleischer DE, Lewis JH, et al. Double-blind controlled trial of the garren-edwards gastric bubble: an adjunctive treatment for exogenous obesity. Gastroenterology. 1988;95(3):581–8 [Clinical Trial Randomized Controlled Trial].

    PubMed  CAS  Google Scholar 

  22. Genco A, Bruni T, Doldi SB, Forestieri P, Marino M, Busetto L, et al. Bioenterics intragastric balloon: the Italian experience with 2,515 patients. Obes Surg. 2005;15(8):1161–4.

    Article  PubMed  CAS  Google Scholar 

  23. Sandler BJ, Rumbaut R, Swain CP, Torres G, Morales L, Gonzales L, et al. Human experience with an endoluminal, endoscopic, gastrojejunal bypass sleeve. Surg Endosc. 2011;25(9):3028–33 [Clinical Trial].

    Article  PubMed  Google Scholar 

  24. Rodriguez-Grunert L, Galvao Neto MP, Alamo M, Ramos AC, Baez PB, Tarnoff M. First human experience with endoscopically delivered and retrieved duodenal-jejunal bypass sleeve. Surg Obes Relat Dis. 2008;4(1):55–9 [Clinical Trial].

    Article  PubMed  Google Scholar 

  25. Tarnoff M, Rodriguez L, Escalona A, Ramos A, Neto M, Alamo M, et al. Open label, prospective, randomized controlled trial of an endoscopic duodenal-jejunal bypass sleeve versus low calorie diet for pre-operative weight loss in bariatric surgery. Surg Endosc. 2009;23(3):650–6 [Multicenter Study Randomized Controlled Trial].

    Article  PubMed  CAS  Google Scholar 

  26. Gersin KS, Rothstein RI, Rosenthal RJ, Stefanidis D, Deal SE, Kuwada TS, et al. Open-label, sham-controlled trial of an endoscopic duodenojejunal bypass liner for preoperative weight loss in bariatric surgery candidates. Gastrointest Endosc. 2010;71(6):976–82 [Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov’t].

    Article  PubMed  Google Scholar 

  27. Ryou M, Cantillon-Murphy P, Azagury D, Shaikh SN, Ha G, Greenwalt I, et al. Smart self-assembling magnets for endoscopy (samsen) for transoral endoscopic creation of immediate gastrojejunostomy (with video). Gastrointest Endosc. 2011;73(2):353–9 [Comparative Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov’t Video-Audio Media].

    Article  PubMed  Google Scholar 

  28. Talebpour M, Amoli BS. Laparoscopic total gastric vertical plication in morbid obesity. J Laparoendosc Adv Surg Tech A. 2007;17(6):793–8.

    Article  PubMed  Google Scholar 

  29. Brethauer SA, Harris JL, Kroh M, Schauer PR. Laparoscopic gastric plication for treatment of severe obesity. Surg Obes Relat Dis. 2011;7(1):15–22 [Clinical Trial Comparative Study].

    Article  PubMed  Google Scholar 

  30. Anonymous. ASMBS policy statement on gastric plication. Surg Obes Relat Dis. 2011;7(3):262.

    Google Scholar 

  31. Skrekas G, Antiochos K, Stafyla VK. Laparoscopic gastric greater curvature plication: results and complications in a series of 135 patients. Obes Surg. 2011;21(11):1657–63 [Clinical Trial].

    Article  PubMed  Google Scholar 

  32. Huang CK, Lo CH, Shabbir A, Tai CM. Novel bariatric technology: laparoscopic adjustable gastric banded plication: technique and preliminary results. Surg Obes Relat Dis. 2012;8(1):41–5.

    Article  PubMed  Google Scholar 

  33. Chand B. Comment on: novel bariatric technology: laparoscopic adjustable gastric banded plication: technique and preliminary results. Surg Obes Relat Dis. 2012;8(1):46–7 [Comment Editorial].

    Article  PubMed  Google Scholar 

  34. Santoro S, Malzoni CE, Velhote MC, Milleo FQ, Santo MA, Klajner S, et al. Digestive adaptation with intestinal reserve: a neuroendocrine-based operation for morbid obesity. Obes Surg. 2006;16(10):1371–9.

    Article  PubMed  Google Scholar 

  35. Koopmans HS, Sclafani A, Fichtner C, Aravich PF. The effects of ileal transposition on food intake and body weight loss in vmh-obese rats. Am J Clin Nutr. 1982;35(2):284–93 [Research Support, Non-U.S. Gov’t Research Support, U.S. Gov’t, P.H.S.].

    PubMed  CAS  Google Scholar 

  36. Boza C, Gagner M, Devaud N, Escalona A, Munoz R, Gandarillas M. Laparoscopic sleeve gastrectomy with ileal transposition (sgit): a new surgical procedure as effective as gastric bypass for weight control in a porcine model. Surg Endosc. 2008;22(4):1029–34 [Research Support, Non-U.S. Gov’t].

    Article  PubMed  Google Scholar 

  37. DePaula AL, Stival AR, Halpern A, Vencio S. Surgical treatment of morbid obesity: mid-term outcomes of the laparoscopic ileal interposition associated to a sleeve gastrectomy in 120 patients. Obes Surg. 2011;21(5):668–75.

    Article  PubMed  Google Scholar 

  38. Camilleri M, Toouli J, Herrera MF, Kulseng B, Kow L, Pantoja JP, et al. Intra-abdominal vagal blocking (vbloc therapy): clinical results with a new implantable medical device. Surgery. 2008;143(6):723–31 [Controlled Clinical Trial Multicenter Study Research Support, Non-U.S. Gov’t].

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of General Surgery, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH, 44195, USA

    John H. Rodriguez MD

  2. Department of Gastrointestinal Surgery, The Ohio State University Medical Center, 410 West 10th Ave. N717 Doan Hall, Columbus, OH, 43210, USA

    Dean J. Mikami MD

  3. Division of GI/Minimally Invasive Surgery, Surgery Loyola University Medical Center, Stritch School of Medicine, 2160 South First Avenue Bldg., 110- Room 3291, Maywood, IL, 60153, USA

    Bipan Chand MD, FACS, FASMBS, FASGE

Authors
  1. John H. Rodriguez MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Dean J. Mikami MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Bipan Chand MD, FACS, FASMBS, FASGE
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to John H. Rodriguez MD .

Editor information

Editors and Affiliations

  1. Division of Gastrointestinal Surgery, Department of Surgery, University of California, Irvine Medical Center, Orange, California, USA

    Ninh T. Nguyen

  2. Scottsdale Bariatric Center, Scottsdale, Arizona, USA

    Robin P. Blackstone

  3. Section of Bariatric and Minimally Invasive (BMI) Surgery, Stanford School of Medicine, Stanford, California, USA

    John M. Morton

  4. Bariatric Surgery, Hamilton Medical Center, Dalton, Georgia, USA

    Jaime Ponce

  5. Professor of Surgery and Chairman Department of General Surgery Director, The Bariatric and Metabolic Institute Cleveland Clinic, Weston, Florida, USA

    Raul J. Rosenthal

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media New York

About this chapter

Cite this chapter

Rodriguez, J.H., Mikami, D.J., Chand, B. (2015). Experimental Alternatives in Bariatric Surgery. In: Nguyen, N., Blackstone, R., Morton, J., Ponce, J., Rosenthal, R. (eds) The ASMBS Textbook of Bariatric Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1206-3_40

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1206-3_40

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-1205-6

  • Online ISBN: 978-1-4939-1206-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation