Skip to main content
SpringerLink
Log in

Circadian Rhythm Sleep Disorders

  • Chapter
  • First Online:
Primary Care Sleep Medicine

  • 1376 Accesses

Abstract

Nearly all organisms exhibit a near-24 h (circadian) rhythm in physiology and behavior, which in humans is best reflected in the daily pattern of the sleep and wake cycle. These intrinsic rhythms are genetically regulated through a complex transcription–translation feedback loop of specific clock genes. The master pacemaker that generates circadian rhythms is located within the suprachiasmatic nucleus (SCN) in the hypothalamus. The timing and strength of the oscillation of circadian rhythms can be manipulated by strategically timed administration of light and melatonin. Circadian rhythm sleep–wake disorders can result either from endogenous dysfunction of the internal circadian clock, or through exogenous environmental disruption. Treatment of these disorders relies on a combination of specific timing of light and melatonin, along with structured physical and social activity and maintaining a regular sleep–wake schedule.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

ASPD:

Advanced sleep phase disorder

BMAL:

Brain and muscle ARNT-like protein

CK:

Casein kinase

CLOCK:

Circadian locomotor output cycles kaput

CRSD:

Circadian rhythm sleep disorder

DSPD:

Delayed sleep phase disorder

GSK:

Glycogen synthase kinase

ISWD:

Irregular sleep–wake disorder

MR:

Median raphe

N24SD:

Non-24 sleep–wake disorder

PVN:

Paraventricular nucleus

SAD:

Seasonal affective disorder

SCN:

Suprachiasmatic nucleus

SWD:

Shift work disorder

References

  1. Dijk DJ, Czeisler CA. Paradoxical timing of the circadian rhythm of sleep propensity serves to consolidate sleep and wakefulness in humans. Neurosci Lett. 1994;166(1):63–8.

    Article  PubMed  CAS  Google Scholar 

  2. Czeisler CA, Duffy JF, Shanahan TL, Brown EN, Mitchell JF, Rimmer DW, et al. Stability, precision, and near-24-hour period of the human circadian pacemaker. Science. 1999;284(5423):2177–81.

    Article  PubMed  CAS  Google Scholar 

  3. Lamont EW, James FO, Boivin DB, Cermakian N. From circadian clock gene expression to pathologies. Sleep Med. 2007;8(6):547–56.

    Article  PubMed  Google Scholar 

  4. Crumbley C, Burris TP. Direct regulation of CLOCK expression by REV-ERB. PLoS One. 2011;6(3):e17290.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  5. Nagoshi E, Saini C, Bauer C, Laroche T, Naef F, Schibler U. Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells. Cell. 2004;119(5):693–705.

    Article  PubMed  CAS  Google Scholar 

  6. Gooley JJ, Lu J, Chou TC, Scammell TE, Saper CB. Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci. 2001;4(12):1165.

    Article  PubMed  CAS  Google Scholar 

  7. Sadun AA, Schaechter JD, Smith LE. A retinohypothalamic pathway in man: light mediation of circadian rhythms. Brain Res. 1984;302(2):371–7.

    Article  PubMed  CAS  Google Scholar 

  8. Khalsa SB, Jewett ME, Cajochen C, Czeisler CA. A phase response curve to single bright light pulses in human subjects. J Physiol. 2003;549(Pt 3):945–52.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  9. Lewy AJ, Sack RL. The dim light melatonin onset as a marker for circadian phase position. Chronobiol Int. 1989;6(1):93–102.

    Article  PubMed  CAS  Google Scholar 

  10. Lewy AJ, Ahmed S, Jackson JM, Sack RL. Melatonin shifts human circadian rhythms according to a phase-response curve. Chronobiol Int. 1992;9(5):380–92.

    Article  PubMed  CAS  Google Scholar 

  11. Burgess HJ, Revell VL, Molina TA, Eastman CI. Human phase response curves to three days of daily melatonin: 0.5 mg versus 3.0 mg. J Clin Endocrinol Metab. 2010;95(7):3325–31.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  12. Cheung PW, McCormack CE. Failure of pinealectomy or melatonin to alter circadian activity rhythm of the rat. Am J Physiol. 1982;242(3):R261–4.

    PubMed  CAS  Google Scholar 

  13. Verheggen RJ, Jones H, Nyakayiru J, Thompson A, Groothuis JT, Atkinson G, et al. Complete absence of evening melatonin increase in tetraplegics. FASEB J. 2012;26(7):3059–64.

    Article  PubMed  CAS  Google Scholar 

  14. Bobrzynska KJ, Godfrey MH, Mrosovsky N. Serotonergic stimulation and nonphotic phase-shifting in hamsters. Physiol Behav. 1996;59(2):221–30.

    Article  PubMed  CAS  Google Scholar 

  15. Dai J, Swaab DF, Van der Vliet J, Buijs RM. Postmortem tracing reveals the organization of hypothalamic projections of the suprachiasmatic nucleus in the human brain. J Comp Neurol. 1998;400(1):87–102.

    Article  PubMed  CAS  Google Scholar 

  16. American Academy of Sleep Medicine. The international classification of sleep disorders: diagnostic and coding manual. 2nd ed. Westchester, IL: American Academy of Sleep Medicine; 2005. xviii, p 297.

    Google Scholar 

  17. Morgenthaler TI, Lee-Chiong T, Alessi C, Friedman L, Aurora RN, Boehlecke B, et al. Practice parameters for the clinical evaluation and treatment of circadian rhythm sleep disorders. An American Academy of Sleep Medicine report. Sleep. 2007;30(11):1445–59.

    PubMed  PubMed Central  Google Scholar 

  18. Reid KJ, Chang AM, Dubocovich ML, Turek FW, Takahashi JS, Zee PC. Familial advanced sleep phase syndrome. Arch Neurol. 2001;58(7):1089–94.

    Article  PubMed  CAS  Google Scholar 

  19. Jones CR, Campbell SS, Zone SE, Cooper F, DeSano A, Murphy PJ, et al. Familial advanced sleep-phase syndrome: a short-period circadian rhythm variant in humans. Nat Med. 1999;5(9):1062–5.

    Article  PubMed  CAS  Google Scholar 

  20. Toh KL, Jones CR, He Y, Eide EJ, Hinz WA, Virshup DM, et al. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science. 2001;291(5506):1040–3.

    Article  PubMed  CAS  Google Scholar 

  21. Xu Y, Padiath QS, Shapiro RE, Jones CR, Wu SC, Saigoh N, et al. Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome. Nature. 2005;434(7033):640–4.

    Article  PubMed  CAS  Google Scholar 

  22. Shanware NP, Hutchinson JA, Kim SH, Zhan L, Bowler MJ, Tibbetts RS. Casein kinase 1-dependent phosphorylation of familial advanced sleep phase syndrome-associated residues controls PERIOD 2 stability. J Biol Chem. 2011;286(14):12766–74.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  23. Vanselow K, Vanselow JT, Westermark PO, Reischl S, Maier B, Korte T, et al. Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS). Genes Dev. 2006;20(19):2660–72.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  24. Xu Y, Toh KL, Jones CR, Shin JY, Fu YH, Ptacek LJ. Modeling of a human circadian mutation yields insights into clock regulation by PER2. Cell. 2007;128(1):59–70.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  25. Lee HM, Chen R, Kim H, Etchegaray JP, Weaver DR, Lee C. The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1. Proc Natl Acad Sci U S A. 2011;108(39):16451–6.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  26. Lack L, Wright H. The effect of evening bright light in delaying the circadian rhythms and lengthening the sleep of early morning awakening insomniacs. Sleep. 1993;16(5):436–43.

    PubMed  CAS  Google Scholar 

  27. Lack L, Wright H, Kemp K, Gibbon S. The treatment of early-morning awakening insomnia with 2 evenings of bright light. Sleep. 2005;28(5):616–23.

    PubMed  Google Scholar 

  28. Zee PC. Melatonin for the treatment of advanced sleep phase disorder. Sleep. 2008;31(7):923; author reply 5.

    Google Scholar 

  29. Kripke DF, Rex KM, Ancoli-Israel S, Nievergelt CM, Klimecki W, Kelsoe JR. Delayed sleep phase cases and controls. J Circadian Rhythms. 2008;6:6.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Saxvig IW, Pallesen S, Wilhelmsen-Langeland A, Molde H, Bjorvatn B. Prevalence and correlates of delayed sleep phase in high school students. Sleep Med. 2012;13(2):193–9.

    Article  PubMed  Google Scholar 

  31. Weitzman ED, Czeisler CA, Coleman RM, Spielman AJ, Zimmerman JC, Dement W, et al. Delayed sleep phase syndrome. A chronobiological disorder with sleep-onset insomnia. Arch Gen Psychiatry. 1981;38(7):737–46.

    Article  PubMed  CAS  Google Scholar 

  32. Ebisawa T, Uchiyama M, Kajimura N, Mishima K, Kamei Y, Katoh M, et al. Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome. EMBO Rep. 2001;2(4):342–6.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  33. Archer SN, Robilliard DL, Skene DJ, Smits M, Williams A, Arendt J, et al. A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep. 2003;26(4):413–5.

    PubMed  Google Scholar 

  34. Mishima K, Tozawa T, Satoh K, Saitoh H, Mishima Y. The 3111T/C polymorphism of hClock is associated with evening preference and delayed sleep timing in a Japanese population sample. Am J Med Genet B Neuropsychiatr Genet. 2005;133B(1):101–4.

    Article  PubMed  Google Scholar 

  35. Pedrazzoli M, Louzada FM, Pereira DS, Benedito-Silva AA, Lopez AR, Martynhak BJ, et al. Clock polymorphisms and circadian rhythms phenotypes in a sample of the Brazilian population. Chronobiol Int. 2007;24(1):1–8.

    Article  PubMed  CAS  Google Scholar 

  36. Quinto C, Gellido C, Chokroverty S, Masdeu J. Posttraumatic delayed sleep phase syndrome. Neurology. 2000;54(1):250–2.

    Article  PubMed  CAS  Google Scholar 

  37. Nagtegaal JE, Kerkhof GA, Smits MG, Swart AC, van der Meer YG. Traumatic brain injury-associated delayed sleep phase syndrome. Funct Neurol. 1997;12(6):345–8.

    PubMed  CAS  Google Scholar 

  38. Patten SB, Lauderdale WM. Delayed sleep phase disorder after traumatic brain injury. J Am Acad Child Adolesc Psychiatry. 1992;31(1):100–2.

    Article  PubMed  CAS  Google Scholar 

  39. Ayalon L, Borodkin K, Dishon L, Kanety H, Dagan Y. Circadian rhythm sleep disorders following mild traumatic brain injury. Neurology. 2007;68(14):1136–40.

    Article  PubMed  CAS  Google Scholar 

  40. Boone DR, Sell SL, Micci MA, Crookshanks JM, Parsley M, Uchida T, et al. Traumatic brain injury-induced dysregulation of the circadian clock. PLoS One. 2012;7(10):e46204.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  41. Abe T, Inoue Y, Komada Y, Nakamura M, Asaoka S, Kanno M, et al. Relation between morningness–eveningness score and depressive symptoms among patients with delayed sleep phase syndrome. Sleep Med. 2011;12(7):680–4.

    Article  PubMed  Google Scholar 

  42. Lee HJ, Rex KM, Nievergelt CM, Kelsoe JR, Kripke DF. Delayed sleep phase syndrome is related to seasonal affective disorder. J Affect Disord. 2011;133(3):573–9.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Reid KJ, Jaksa AA, Eisengart JB, Baron KG, Lu B, Kane P, et al. Systematic evaluation of Axis-I DSM diagnoses in delayed sleep phase disorder and evening-type circadian preference. Sleep Med. 2012;13(9):1171–7.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Sack RL, Auckley D, Auger RR, Carskadon MA, Wright Jr KP, Vitiello MV, et al. Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep–wake rhythm. An American Academy of Sleep Medicine review. Sleep. 2007;30(11):1484–501.

    PubMed  PubMed Central  Google Scholar 

  45. Dagan Y, Yovel I, Hallis D, Eisenstein M, Raichik I. Evaluating the role of melatonin in the long-term treatment of delayed sleep phase syndrome (DSPS). Chronobiol Int. 1998;15(2):181–90.

    Article  PubMed  CAS  Google Scholar 

  46. Nagtegaal JE, Kerkhof GA, Smits MG, Swart AC, Van Der Meer YG. Delayed sleep phase syndrome: a placebo-controlled cross-over study on the effects of melatonin administered five hours before the individual dim light melatonin onset. J Sleep Res. 1998;7(2):135–43.

    Article  PubMed  CAS  Google Scholar 

  47. Kayumov L, Brown G, Jindal R, Buttoo K, Shapiro CM. A randomized, double-blind, placebo-controlled crossover study of the effect of exogenous melatonin on delayed sleep phase syndrome. Psychosom Med. 2001;63(1):40–8.

    Article  PubMed  CAS  Google Scholar 

  48. Mundey K, Benloucif S, Harsanyi K, Dubocovich ML, Zee PC. Phase-dependent treatment of delayed sleep phase syndrome with melatonin. Sleep. 2005;28(10):1271–8.

    PubMed  Google Scholar 

  49. Szeinberg A, Borodkin K, Dagan Y. Melatonin treatment in adolescents with delayed sleep phase syndrome. Clin Pediatr. 2006;45(9):809–18.

    Article  Google Scholar 

  50. Rosenthal NE, Joseph-Vanderpool JR, Levendosky AA, Johnston SH, Allen R, Kelly KA, et al. Phase-shifting effects of bright morning light as treatment for delayed sleep phase syndrome. Sleep. 1990;13(4):354–61.

    PubMed  CAS  Google Scholar 

  51. Cole RJ, Smith JS, Alcala YC, Elliott JA, Kripke DF. Bright-light mask treatment of delayed sleep phase syndrome. J Biol Rhythms. 2002;17(1):89–101.

    Article  PubMed  Google Scholar 

  52. Gradisar M, Dohnt H, Gardner G, Paine S, Starkey K, Menne A, et al. A randomized controlled trial of cognitive-behavior therapy plus bright light therapy for adolescent delayed sleep phase disorder. Sleep. 2011;34(12):1671–80.

    PubMed  PubMed Central  Google Scholar 

  53. Lewy AJ, Bauer VK, Hasler BP, Kendall AR, Pires ML, Sack RL. Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin. Brain Res. 2001;918(1–2):96–100.

    Article  PubMed  CAS  Google Scholar 

  54. Sack RL, Brandes RW, Kendall AR, Lewy AJ. Entrainment of free-running circadian rhythms by melatonin in blind people. N Engl J Med. 2000;343(15):1070–7.

    Article  PubMed  CAS  Google Scholar 

  55. Brown MA, Quan SF, Eichling PS. Circadian rhythm sleep disorder, free-running type in a sighted male with severe depression, anxiety, and agoraphobia. J Clin Sleep Med. 2011;7(1):93–4.

    PubMed  PubMed Central  Google Scholar 

  56. Kuzniar TJ, Kovacevic-Ristanovic R, Nierodzik CL, Smith LC. Free-running (non-entrained to 24-h period) circadian sleep disorder in a patient with obstructive sleep apnea, delayed sleep phase tendency, and lack of social interaction. Sleep Breath Schlaf Atmung. 2012;16(2):313–5.

    Article  Google Scholar 

  57. Uchiyama M, Okawa M, Shibui K, Kim K, Tagaya H, Kudo Y, et al. Altered phase relation between sleep timing and core body temperature rhythm in delayed sleep phase syndrome and non-24-hour sleep–wake syndrome in humans. Neurosci Lett. 2000;294(2):101–4.

    Article  PubMed  CAS  Google Scholar 

  58. Kitamura S, Hida A, Enomot M, Watanabe M, Katayose Y, Nozaki K, et al. Intrinsic circadian period of sighted patients with circadian rhythm sleep disorder, free-running type. Biol Psychiatry. 2013;73(1):63–9.

    Google Scholar 

  59. Okawa M, Mishima K, Hishikawa Y, Hozumi S, Hori H, Takahashi K. Circadian rhythm disorders in sleep-waking and body temperature in elderly patients with dementia and their treatment. Sleep. 1991;14(6):478–85.

    PubMed  CAS  Google Scholar 

  60. Wasdell MB, Jan JE, Bomben MM, Freeman RD, Rietveld WJ, Tai J, et al. A randomized, placebo-controlled trial of controlled release melatonin treatment of delayed sleep phase syndrome and impaired sleep maintenance in children with neurodevelopmental disabilities. J Pineal Res. 2008;44(1):57–64.

    PubMed  CAS  Google Scholar 

  61. Bourne RS, Mills GH, Minelli C. Melatonin therapy to improve nocturnal sleep in critically ill patients: encouraging results from a small randomised controlled trial. Crit Care. 2008;12(2):R52.

    Article  PubMed  PubMed Central  Google Scholar 

  62. Alessi CA, Martin JL, Webber AP, Cynthia Kim E, Harker JO, Josephson KR. Randomized, controlled trial of a nonpharmacological intervention to improve abnormal sleep/wake patterns in nursing home residents. J Am Geriatr Soc. 2005;53(5):803–10.

    Article  PubMed  Google Scholar 

  63. Statistics UBoL. Workers on Flexible and Shift Schedules. 2004

    Google Scholar 

  64. Drake CL, Roehrs T, Richardson G, Walsh JK, Roth T. Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers. Sleep. 2004;27(8):1453–62.

    PubMed  Google Scholar 

  65. American Academy of Sleep Medicine. ICSD-2 - International classification of sleep disorders: Diagnostic and coding manual. 2nd ed. American Academy of Sleep Medicine, 2005.

    Google Scholar 

  66. Colligan MJ, Rosa RR. Shiftwork effects on social and family life. Occup Med. 1990;5(2):315–22.

    PubMed  CAS  Google Scholar 

  67. Pan A, Schernhammer ES, Sun Q, Hu FB. Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women. PLoS Med. 2011;8(12):e1001141.

    Article  PubMed  PubMed Central  Google Scholar 

  68. Viitasalo K, Lindstrom J, Hemio K, Puttonen S, Koho A, Harma M, et al. Occupational health care identifies risk for type 2 diabetes and cardiovascular disease. Prim Care Diabetes. 2012;6(2):95–102.

    Article  PubMed  Google Scholar 

  69. Monk TH, Buysse DJ. Exposure to shift work as a risk factor for diabetes. J Biol Rhythms. 2013;28(5):356–9.

    Article  PubMed  Google Scholar 

  70. Brown DL, Feskanich D, Sanchez BN, Rexrode KM, Schernhammer ES, Lisabeth LD. Rotating night shift work and the risk of ischemic stroke. Am J Epidemiol. 2009;169(11):1370–7.

    Article  PubMed  PubMed Central  Google Scholar 

  71. Antunes LC, Levandovski R, Dantas G, Caumo W, Hidalgo MP. Obesity and shift work: chronobiological aspects. Nutr Res Rev. 2010;23(1):155–68.

    Article  PubMed  CAS  Google Scholar 

  72. Smith P, Fritschi L, Reid A, Mustard C. The relationship between shift work and body mass index among Canadian nurses. Appl Nurs Res. 2013;26(1):24–31.

    Article  PubMed  Google Scholar 

  73. Zhao I, Bogossian F, Song S, Turner C. The association between shift work and unhealthy weight: a cross-sectional analysis from the nurses and midwives’ e-cohort study. J Occup Environ Med. 2011;53(2):153–8.

    Article  PubMed  Google Scholar 

  74. Pukkala E, Auvinen A, Wahlberg G. Incidence of cancer among Finnish airline cabin attendants, 1967–92. BMJ. 1995;311(7006):649–52.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  75. Hansen J. Increased breast cancer risk among women who work predominantly at night. Epidemiology. 2001;12(1):74–7.

    Article  PubMed  CAS  Google Scholar 

  76. Schernhammer ES, Laden F, Speizer FE, Willett WC, Hunter DJ, Kawachi I, et al. Rotating night shifts and risk of breast cancer in women participating in the nurses' health study. J Natl Cancer Inst. 2001;93(20):1563–8.

    Article  PubMed  CAS  Google Scholar 

  77. Gronfier C, Wright Jr KP, Kronauer RE, Jewett ME, Czeisler CA. Efficacy of a single sequence of intermittent bright light pulses for delaying circadian phase in humans. Am J Physiol Endocrinol Metab. 2004;287(1):E174–81.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  78. Buxton OM, L'Hermite-Baleriaux M, Turek FW, van Cauter E. Daytime naps in darkness phase shift the human circadian rhythms of melatonin and thyrotropin secretion. Am J Physiol Regul Integr Comp Physiol. 2000;278(2):R373–82.

    PubMed  CAS  Google Scholar 

  79. Sharkey KM, Eastman CI. Melatonin phase shifts human circadian rhythms in a placebo-controlled simulated night-work study. Am J Physiol Regul Integr Comp Physiol. 2002;282(2):R454–63.

    PubMed  CAS  PubMed Central  Google Scholar 

  80. Schweitzer PK, Randazzo AC, Stone K, Erman M, Walsh JK. Laboratory and field studies of naps and caffeine as practical countermeasures for sleep–wake problems associated with night work. Sleep. 2006;29(1):39–50.

    PubMed  Google Scholar 

  81. Czeisler CA, Walsh JK, Roth T, Hughes RJ, Wright KP, Kingsbury L, et al. Modafinil for excessive sleepiness associated with shift-work sleep disorder. N Engl J Med. 2005;353(5):476–86.

    Article  PubMed  CAS  Google Scholar 

  82. Moon CA, Hindmarch I, Holland RL. The effect of zopiclone 7.5 mg on the sleep, mood and performance of shift workers. Int Clin Psychopharmacol. 1990;5 Suppl 2:79–83.

    PubMed  Google Scholar 

  83. Hart CL, Ward AS, Haney M, Foltin RW. Zolpidem-related effects on performance and mood during simulated night-shift work. Exp Clin Psychopharmacol. 2003;11(4):259–68.

    Article  PubMed  CAS  Google Scholar 

  84. Lee C, Smith MR, Eastman CI. A compromise phase position for permanent night shift workers: circadian phase after two night shifts with scheduled sleep and light/dark exposure. Chronobiol Int. 2006;23(4):859–75.

    Article  PubMed  Google Scholar 

  85. Smith MR, Fogg LF, Eastman CI. A compromise circadian phase position for permanent night work improves mood, fatigue, and performance. Sleep. 2009;32(11):1481–9.

    PubMed  PubMed Central  Google Scholar 

  86. Lowden A, Akerstedt T. Retaining home-base sleep hours to prevent jet lag in connection with a westward flight across nine time zones. Chronobiol Int. 1998;15(4):365–76.

    Article  PubMed  CAS  Google Scholar 

  87. Eastman CI, Gazda CJ, Burgess HJ, Crowley SJ, Fogg LF. Advancing circadian rhythms before eastward flight: a strategy to prevent or reduce jet lag. Sleep. 2005;28(1):33–44.

    PubMed  PubMed Central  Google Scholar 

  88. Rosenberg RP, Bogan RK, Tiller JM, Yang R, Youakim JM, Earl CQ, et al. A phase 3, double-blind, randomized, placebo-controlled study of armodafinil for excessive sleepiness associated with jet lag disorder. Mayo Clin Proc Mayo Clinic. 2010;85(7):630–8.

    Article  CAS  Google Scholar 

  89. Angeles-Castellanos M, Amaya JM, Salgado-Delgado R, Buijs RM, Escobar C. Scheduled food hastens re-entrainment more than melatonin does after a 6-h phase advance of the light–dark cycle in rats. J Biol Rhythms. 2011;26(4):324–34.

    Article  PubMed  CAS  Google Scholar 

  90. Jamieson AO, Zammit GK, Rosenberg RS, Davis JR, Walsh JK. Zolpidem reduces the sleep disturbance of jet lag. Sleep Med. 2001;2(5):423–30.

    Article  PubMed  CAS  Google Scholar 

  91. Suhner A, Schlagenhauf P, Hofer I, Johnson R, Tschopp A, Steffen R. Effectiveness and tolerability of melatonin and zolpidem for the alleviation of jet lag. Aviat Space Environ Med. 2001;72(7):638–46.

    PubMed  CAS  Google Scholar 

  92. Daurat A, Benoit O, Buguet A. Effects of zopiclone on the rest/activity rhythm after a westward flight across five time zones. Psychopharmacology (Berl). 2000;149(3):241–5.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurology, Northwestern University, 710 North Lake Shore Drive, Chicago, IL, 60611, USA

    Sabra M. Abbott M.D., Ph.D.

  2. Circadian Rhythms & Sleep Research Laboratory, 710 N Lake Shore Drive, Chicago, IL, 60611, USA

    Rodolfo Soca M.D.

  3. Department of Neurology, Northwestern Memorial Hospital, 710 N. Lake Shore Drive, Chicago, IL, 60611, USA

    Phyllis C. Zee M.D., Ph.D.

Authors
  1. Sabra M. Abbott M.D., Ph.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rodolfo Soca M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Phyllis C. Zee M.D., Ph.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Phyllis C. Zee M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Sleep Disorders Center, Pueblo, Colorado, USA

    James F. Pagel

  2. Department of Population Health, New York University School of Medicine / Center for Healthful Behavior Change, New York, New York, USA

    S. R. Pandi-Perumal

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Science+Business Media New York

About this chapter

Cite this chapter

Abbott, S.M., Soca, R., Zee, P.C. (2014). Circadian Rhythm Sleep Disorders. In: Pagel, J., Pandi-Perumal, S. (eds) Primary Care Sleep Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1185-1_27

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1185-1_27

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-1184-4

  • Online ISBN: 978-1-4939-1185-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation