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Retroperitoneoscopic Approaches for Infected Necrotizing Pancreatitis

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Prediction and Management of Severe Acute Pancreatitis

Abstract

Over the last decades the treatment of severe acute pancreatitis has changed considerably. Interventional management is primarily indicated in case of infection of necrotizing pancreatitis, and intervention is postponed until pancreatic necrosis is walled-off. Minimally invasive radiological, endoscopic, and surgical techniques seem to have many advantages in comparison with open surgery.

Several techniques of minimally invasive necrosectomy have been developed to facilitate removal of infected necrosis. A retroperitoneoscopic approach is one of the most commonly used minimally invasive techniques. This chapter discusses the background, context, and techniques of retroperitoneoscopic approaches for infected necrotizing pancreatitis.

Percutaneous catheter drainage should be the first step of treatment in infected necrotizing pancreatitis. In about two-thirds of patients there is a need for additional necrosectomy. There are no randomized studies that have investigated which surgical technique for necrosectomy is superior in patients in whom percutaneous catheter drainage has failed. Sinus tract endoscopy and video-assisted retroperitoneal debridement (VARD) seem to be safe and effective retroperitoneoscopic techniques.

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References

  1. Uhl W, Warshaw A, Imrie C, Bassi C, McKay CJ, Lankisch PG, et al. IAP guidelines for the surgical management of acute pancreatitis. Pancreatology. 2002;2:565–73.

    Article  PubMed  Google Scholar 

  2. Van Santvoort HC, Bakker OJ, Bollen TL, Besselink MG, Ahmed Ali U, Schrijver AM, et al. A conservative and minimally invasive approach to necrotizing pancreatitis improves outcome. Gastroenterology. 2011;141:1254–63.

    Article  PubMed  Google Scholar 

  3. Banks PA, Freeman ML. Practice guidelines in acute pancreatitis. Am J Gastroenterol. 2006;101:2379–400.

    Article  PubMed  Google Scholar 

  4. Nathens AB, Curtis JR, Beale RJ, Cook DJ, Moreno RP, Romand JA, et al. Management of the critically ill patient with severe acute pancreatitis. Crit Care Med. 2004;32:2524–36.

    Article  PubMed  Google Scholar 

  5. Besselink MGH, van Santvoort HC, Bakker OJ, Bollen TL, Gooszen HG. Draining sterile fluid collections in acute pancreatitis? Primumnon nocere! Surg Endosc. 2011;25:331–32.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Zerem E, Imamovic G, Omerovic S, Imširović B. Randomized controlled trial on sterile fluid collections management in acute pancreatitis: should they be removed? Surg Endosc. 2009;23:2770–77.

    Article  PubMed  Google Scholar 

  7. Beger HG, Bittner R, Blok S, Büchler M. Bacterial contamination of pancreatic necrosis—a prospective clinical study. Gastroenterology. 1986;91:433–41.

    PubMed  CAS  Google Scholar 

  8. Van Santvoort HC, Besselink MG, Bakker OJ, Hofker HS, Boermeester MA, Dejong CH, et al. A step-up approach or open necrosectomy for necrotizing pancreatitis. N Engl J Med. 2010;362:1491–502.

    Article  PubMed  Google Scholar 

  9. Working Group IAP/APA Acute Pancreatitis Guidelines. IAP/APA evidence-based guidelines for the management of acute pancreatitis. Pancreatology. 2013;13:e1–e15.

    Article  Google Scholar 

  10. Werner J, Feuerbach S, Uhl W, Büchler MW. Management of acute pancreatitis: from surgery to interventional intensive care. Gut. 2005;4:426–36.

    Article  Google Scholar 

  11. Raraty MG, Halloran CM, Dodd S, Ghaneh P, Connor S, Evans J, et al. Minimal access retroperitoneal pancreatic necrosectomy: improvement in morbidity and mortality with a less invasive approach. Ann Surg. 2010;251:787–93.

    Article  PubMed  Google Scholar 

  12. Shelat VG, Diddapur RK. Minimally invasive retroperitoneal pancreatic necrosectomy in necrotising pancreatitis. Singapore Med J. 2007;48:e220–3.

    PubMed  CAS  Google Scholar 

  13. Gagner M. Laparoscopic treatment of acute necrotizing pancreatitis. Semin Laparosc Surg. 1996;3:21–8.

    PubMed  Google Scholar 

  14. Fagniez P, Rotman N, Kracht M. Direct retroperitoneal approach to necrosis in severe acute pancreatitis. Br J Surg. 1989;76:264–7.

    Article  PubMed  CAS  Google Scholar 

  15. Villazon A, Villazon O, Terrazas F, Raña R. Retroperitoneal drainage in the management of the septic phase of severe acute pancreatitis. World J Surg. 1991;15:103–7.

    Article  PubMed  CAS  Google Scholar 

  16. Nakasaki H, Tajimi T, Fujii K, Makuuchi H. A surgical treatment of infected pancreatic necrosis: retroperitoneal laparotomy. Dig Surg. 1999;16:506–11.

    Article  PubMed  CAS  Google Scholar 

  17. Gambiez LP, Denimal FA, Porte HL, Saudemont A, Chambon JP, Quandalle PA. Retroperitoneal approach and endoscopic management of peripancreatic necrosis collections. Arch Surg. 1998;133:66–72.

    Article  PubMed  CAS  Google Scholar 

  18. Castellanos G, Pinero A, Serrano A, Parrilla P. Infected pancreatic necrosis translumbar approach and management with retroperitoneoscopy. Arch Surg. 2002;137:1060–62.

    Article  PubMed  Google Scholar 

  19. Carter CR, McKay CJ, Imrie CW. Percutaneous necrosectomy and sinus tract endoscopy in the management of infected pancreatic necrosis: an initial experience. Ann Surg. 2000;232:175–80.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  20. Connor S, Ghaneh P, Raraty M, Sutton R, Rosso E, Garvey CJ, et al. Minimally invasive retroperitoneal pancreatic necrosectomy. Dig Surg. 2003;20:270–77.

    Article  PubMed  CAS  Google Scholar 

  21. Horvath KD, Kao LS, Ali A, Pellegrini CA, Sinanan MN. Laparoscopic assisted percutaneous drainage of infected pancreatic necrosis. Surg Endosc. 2001; 15:677–82.

    Article  PubMed  CAS  Google Scholar 

  22. Horvath KD, Kao LS, Wherry KL, Pellegrini CA, Sinanan MN. A technique for laparoscopic-assisted percutaneous drainage of infected pancreatic necrosis and pancreatic abscess. Surg Endosc. 2001;15:1221–25.

    Article  PubMed  CAS  Google Scholar 

  23. Van Santvoort HC, Besselink MG, Horvath KD, Sinanan MN, Bollen TL, van Ramshorst B. Videoscopic assisted retroperitoneal debridement in infected necrotizing pancreatitis. HPB. 2007;9: 156–59.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Besselink MG, van Santvoort HC, Schaapherder AF, van Ramshorst B, van Goor H, Gooszen HG, Dutch Acute Pancreatitis Study Group. Feasibility of minimally invasive approaches in patients with infected necrotizing pancreatitis. Br J Surg. 2007;94:604–8.

    Article  PubMed  CAS  Google Scholar 

  25. Van Brunschot S, Besselink MG, Bakker OJ, Boermeester MA, Gooszen HG, Horvath KD, van Santvoort HC. Video-assisted retroperitoneal debridement (VARD) of infected necrotizing pancreatitis: an update. Curr Surg Rep. 2013;1:121–30.

    Article  Google Scholar 

  26. Horvath K, Freeny P, Escallon J, Heagerty P, Comstock B, Glickerman DJ, et al. Safety and efficacy of video-assisted retroperitoneal debridement for infected pancreatic collections: a multicenter, prospective, single-arm phase 2 study. Arch Surg. 2010; 145:817–25.

    Article  PubMed  Google Scholar 

  27. Tenner S, Baillie J, DeWitt J, Vege SS, American College of Gastroenterology. American College of Gastroenterology guidelines: management of acute pancreatitis. Am J Gastroenterol. 2013;108:1400–15.

    Article  PubMed  CAS  Google Scholar 

  28. Van Baal MC, Van Santvoort HC, Bollen TL, Bakker OJ, Besselink MG, Gooszen HG, Dutch Pancreatitis Study Group. Systematic review of percutaneous catheter drainage as primary treatment for necrotizing pancreatitis. Br J Surg. 2011;98:18–27.

    Article  PubMed  Google Scholar 

  29. Mouli VP, Sreenivas V, Garg PK. Efficacy of conservative treatment, without necrosectomy, for infected pancreatic necrosis: a systematic review and meta-analysis. Gastroenterology. 2013;144:333–40.

    Article  PubMed  Google Scholar 

  30. Besselink MG, Verwer TJ, Schoenmaeckers EJ, Buskens E, Ridwan BU, Visser MR, et al. Timing of surgical intervention in necrotizing pancreatitis. Arch Surg. 2007;142:1194–201.

    Article  PubMed  Google Scholar 

  31. Baron TH, Thaggard WG, Morgan DE, Stanley RJ. Endoscopic therapy for organized pancreatic necrosis. Gastroenterology. 1996;111:755–64.

    Article  PubMed  CAS  Google Scholar 

  32. Seifert H, Biermer M, Schmitt W, Jürgensen C, Will U, Gerlach R, et al. Transluminal endoscopic necrosectomy after acute pancreatitis: a multicentre study with long-term follow-up (the GEPARD Study). Gut. 2009;58:1260–66.

    Article  PubMed  CAS  Google Scholar 

  33. Bakker OJ, van Santvoort HC, van Brunschot S, Geskus RB, Besselink MG, Bollen TL, et al. Endoscopic transgastric vs surgical necrosectomy for infected necrotizing pancreatitis: a randomized trial. JAMA. 2012;307:1053–61.

    Article  PubMed  CAS  Google Scholar 

  34. Van Brunschot S, van Grinsven J, Voermans RP, Bakker OJ, Besselink MG, Boermeester MA, et al. Transluminal endoscopic step-up approach versus minimally invasive surgical step-up approach in patients with infected necrotising pancreatitis (TENSION trial): design and rationale of a randomised controlled multicenter trial [ISRCTN09186711]. BMC Gastroenterol. 2013;13:161.

    Article  PubMed  Google Scholar 

  35. Van Brunschot S, Bakker OJ, Besselink MG, Bollen TL, Fockens P, Gooszen HG, et al. Treatment of necrotizing pancreatitis. Clin Gastroenterol Hepatol. 2012;10:1190–201 (figure 5 from the orginal article).

    Google Scholar 

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Correspondence to Hjalmar C. van Santvoort M.D., Ph.D. .

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van Grinsven, J., Besselink, M.G., Bakker, O.J., van Brunschot, S., Boermeester, M.A., van Santvoort, H.C. (2015). Retroperitoneoscopic Approaches for Infected Necrotizing Pancreatitis. In: Forsmark, C., Gardner, T. (eds) Prediction and Management of Severe Acute Pancreatitis. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0971-1_15

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  • DOI: https://doi.org/10.1007/978-1-4939-0971-1_15

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