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Lessons on Kidney Development from Experimental Studies

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Kidney Development in Renal Pathology

Part of the book series: Current Clinical Pathology ((CCPATH))

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Abstract

The development of human kidney is a complex process requiring intricate cell and tissue interactions to assure the concerted program of cell growth, differentiation, and morphogenesis. Although the molecular and cellular nature of each of these interactions remains currently unclear, significant findings regarding nephrogenesis and its completion among different animal species have been reported over the last two decades. Research so far indicates that there are differences regarding the completion of the process of nephrogenesis among different animal species. In human, sheep, and spiny mouse, nephrogenesis is completed prior to birth, while in rat, mouse, and swine, nephrogenesis continuous after birth.

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Authors and Affiliations

  1. Department of Cardiopulmonary Resuscitation, National and Kapodistrian University of Athens, Medical School, Athens, Greece

    Athanasios Chalkias M.D., M.Sc., Ph.D.

  2. Department of Paediatrics, National and Kapodistrian University of Athens Medical School, Athens University, Athens, Greece

    Angeliki Syggelou M.D.

  3. Neonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, Azienda Ospedaliera Universitaria Cagliari, Strada Statale 554, bivio Sestu, Cagliari, 09042, Italy

    Vassilios Fanos M.D.

  4. Department of Surgery, University of Cagliari, Strada Statale 554, bivio Sestu, Cagliari, 09042, Italy

    Vassilios Fanos M.D.

  5. “Cardiopulmonary Resuscitation”, University of Athens, Athens, Greece

    Theodoros Xanthos Ph.D.

  6. Second Department of Obstetrics and Gynecology, Aretaieion Hospital, Athens, Greece

    Nicoletta Iacovidou PhD

Authors
  1. Athanasios Chalkias M.D., M.Sc., Ph.D.
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  2. Angeliki Syggelou M.D.
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  3. Vassilios Fanos M.D.
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  4. Theodoros Xanthos Ph.D.
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  5. Nicoletta Iacovidou PhD
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Correspondence to Vassilios Fanos M.D. .

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Editors and Affiliations

  1. Department of Surgical Sciences, Division of Pathology, Azienda Ospedaliera Universitaria and University of Cagliari, Cagliari, Italy and Temple University, Philadelphia, Pennsylvania, USA

    Gavino Faa

  2. Neonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, and Department of Surgery, Azienda Ospedaliera Universitaria Cagliari, Cagliari, Italy and University of Cagliari, Cagliari, Italy, Cagliari, Italy

    Vassilios Fanos

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Chalkias, A., Syggelou, A., Fanos, V., Xanthos, T., Iacovidou, N. (2014). Lessons on Kidney Development from Experimental Studies. In: Faa, G., Fanos, V. (eds) Kidney Development in Renal Pathology. Current Clinical Pathology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-0947-6_7

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