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Fascioliasis

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Digenetic Trematodes

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 766))

Abstract

Fascioliasis is a major parasitic disease caused by the digenetic trematodes Fasciola hepatica and Fasciola gigantica. The disease is a well-known veterinary problem of worldwide distribution. Fascioliasis is the vector-borne parasitic disease presenting the widest latitudinal, longitudinal and altitudinal distribution known at present. In the last two decades, many surveys have shown it to be an important public health problem as well, including estimations of 2.4 million, up to 17 million people, or even higher depending from the hitherto unknown situations mainly in several regions of Asia and Africa. In recent years, the increasing number of human case reports in many countries of the five continents and the results of studies on pathogenicity and immunity, mainly regarding the chronic period of the disease, are the reasons why it has been decided to no longer consider fascioliasis merely a secondary zoonotic disease, but an important human parasitic disease. In this chapter, we review the most relevant features in relation to fascioliasis, including from the most traditional to the most innovative aspects.

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Acknowledgements

Reviews of fascioliasis carried out within Projects SAF2010-20805 of the Ministry of Economy and Competitiveness, Madrid, Spain; ISCIII-RETIC RD12/0018/0013, Red de Investigación de Centros de Enfermedades Tropicales—RICET, of the Program of Redes Temáticas de Investigación Cooperativa RETICS/FEDER, Ministry of Health and Consumption, Madrid, Spain; and PROMETEO/2012/042, of the Program of Ayudas para Grupos de Investigación de Excelencia, Generalitat Valenciana, Valencia, Spain.

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  1. Departamento de Biología Celular y Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andrés Estellés s/n Burjassot, 46100, Valencia, Spain

    Santiago Mas-Coma, M. Adela Valero & M. Dolores Bargues

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  1. Santiago Mas-Coma
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  2. M. Adela Valero
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  3. M. Dolores Bargues
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Correspondence to Santiago Mas-Coma .

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  1. Departamento de Biología Celular,Parasitología Facultad de Farmacia, University of Valencia, Burjassot, Valencia, Spain

    Rafael Toledo

  2. Department of Biology, Lafayette College, Easton, Pennsylvania, USA

    Bernard Fried

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Mas-Coma, S., Valero, M.A., Bargues, M.D. (2014). Fascioliasis. In: Toledo, R., Fried, B. (eds) Digenetic Trematodes. Advances in Experimental Medicine and Biology, vol 766. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0915-5_4

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