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Lung Cancer in HIV Infection

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Cancers in People with HIV and AIDS

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Abstract

The term lung cancer is usually used to describe any of several types of primary tumors arising in the lung; common histological types include adenocarcinoma, squamous cell carcinoma, large cell carcinoma, bronchoalveolar cancer, and small cell lung cancer. Taken together, lung cancer is the most common non-AIDS-defining malignancy in HIV-infected individuals. Lung cancer risk appears to be two to five times greater in the HIV-infected persons compared to the general population, and most epidemiological studies find that the risk remains high even after adjusting for other factors like smoking intensity and duration. Often these patients present with advanced disease at a younger age but may have comparable survival compared with similarly matched lung cancer patients without HIV infection. Smoking cessation is the most effective preventive strategy.

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Author information

Authors and Affiliations

  1. Division of Internal Medicine, Multicare Good Samaritan Hospital, Puyallup, WA, USA

    Deepthi Mani

  2. Division of Hematology and Oncology, Virginia Mason Medical Center, 1100 Ninth Avenue, 900 (C2-HEM), Seattle, WA, 98111, USA

    David M. Aboulafia M.D.

  3. Division of Hematology, University of Washington, Seattle, WA, USA

    David M. Aboulafia M.D.

Authors
  1. Deepthi Mani
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  2. David M. Aboulafia M.D.
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Corresponding author

Correspondence to David M. Aboulafia M.D. .

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Editors and Affiliations

  1. National Cancer Institute HIV/AIDS Malignancy Branch, National Institutes of Health, Bethesda, Maryland, USA

    Robert Yarchoan

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Mani, D., Aboulafia, D.M. (2014). Lung Cancer in HIV Infection. In: Yarchoan, R. (eds) Cancers in People with HIV and AIDS. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0859-2_22

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