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Dysfunction in Anatomic Outlet Obstruction in Men

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Bladder Dysfunction in the Adult

Part of the book series: Current Clinical Urology ((CCU))

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Abstract

Compression, distortion or occlusion of the bladder outlet impedes flow of urine during voiding, leading to characteristic symptoms of hesitancy, poor stream, dribbling and incomplete emptying. Benign prostate enlargement (BPE) and urethral stricture are the most common causes in men. Secondary changes in the lower urinary tract can result, which affect the structure and physiology and may additionally lead to storage phase symptoms, though the latter may also arise incidentally. Diagnostic tests are needed to understand mechanisms and contributory factors. Most men are investigated with measurement of free flow rate tests and post-void residual. In men with BPE, invasive urodynamic testing enables confirmation of bladder outlet obstruction and exclusion of detrusor underactivity. In urethral stricture disease, endoscopic examination and imaging are used to obtain the diagnosis and severity of the problem.

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References

  1. Wein AJ. Classification of neurogenic voiding dysfunction. J Urol. 1981;125:605–9.

    CAS  PubMed  Google Scholar 

  2. Abrams P, Cardozo L, Fall M, et al. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn. 2002;21:167–78.

    Article  PubMed  Google Scholar 

  3. Abrams P. New words for old: lower urinary tract symptoms for “prostatism”. BMJ. 1994;308:929–30.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  4. Irwin DE, Milsom I, Hunskaar S, et al. Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study. Eur Urol. 2006;50:1306–14; discussion 14–5.

    Article  PubMed  Google Scholar 

  5. Irwin DE, Kopp ZS, Agatep B, Milsom I, Abrams P. Worldwide prevalence estimates of lower urinary tract symptoms, overactive bladder, urinary incontinence and bladder outlet obstruction. BJU Int. 2011;108:1132–8.

    Article  PubMed  Google Scholar 

  6. Galosi AB, Mazzaferro D, Lacetera V, Muzzonigro G, Martino P, Tucci G. Modifications of the bladder wall (organ damage) in patients with bladder outlet obstruction: ultrasound parameters. Arch Ital Urol Androl. 2012;84:263–7.

    PubMed  Google Scholar 

  7. Drzewiecki BA, Anumanthan G, Penn HA, et al. Modulation of the hypoxic response following partial bladder outlet obstruction. J Urol. 2012;188:1549–54.

    Article  PubMed  Google Scholar 

  8. Greenland JE, Brading AF. The effect of bladder outflow obstruction on detrusor blood flow changes during the voiding cycle in conscious pigs. J Urol. 2001;165:245–8.

    Article  CAS  PubMed  Google Scholar 

  9. Greenland JE, Hvistendahl JJ, Andersen H, et al. The effect of bladder outlet obstruction on tissue oxygen tension and blood flow in the pig bladder. BJU Int. 2000;85:1109–14.

    Article  CAS  PubMed  Google Scholar 

  10. Brading AF, Turner WH. The unstable bladder: towards a common mechanism. Br J Urol. 1994;73:3–8.

    Article  CAS  PubMed  Google Scholar 

  11. Maciejewski CC, Honardoust D, Tredget EE, Metcalfe PD. Differential expression of class I small leucine-rich proteoglycans in an animal model of partial bladder outlet obstruction. J Urol. 2012;188:1543–8.

    Article  CAS  PubMed  Google Scholar 

  12. Kim SO, Oh BS, Chang IY, et al. Distribution of interstitial cells of Cajal and expression of nitric oxide synthase after experimental bladder outlet obstruction in a rat model of bladder overactivity. Neurourol Urodyn. 2011;30:1639–45.

    Article  PubMed  CAS  Google Scholar 

  13. Birder LA. Involvement of the urinary bladder urothelium in signaling in the lower urinary tract. Proc West Pharmacol Soc. 2001;44:85–6.

    CAS  PubMed  Google Scholar 

  14. Birder LA. Urothelial signaling. Auton Neurosci. 2010;153:33–40.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  15. Bschleipfer T, Weidner W, Kummer W, Lips KS. Does bladder outlet obstruction alter the non-neuronal cholinergic system of the human urothelium? Life Sci. 2012;91:1082–6.

    Article  CAS  PubMed  Google Scholar 

  16. Li Y, Xue L, Miao Q, et al. Expression and electrophysiological characteristics of P2X3 receptors in interstitial cells of Cajal in rats with partial bladder outlet obstruction. BJU Int. 2013;111:843–51.

    Article  CAS  PubMed  Google Scholar 

  17. Sibley GN. The physiological response of the detrusor muscle to experimental bladder outflow obstruction in the pig. Br J Urol. 1987;60:332–6.

    Article  CAS  PubMed  Google Scholar 

  18. Tobu S, Noguchi M, Hatada T, Mori K, Matsuo M, Sakai H. Changes in angiotensin II type 1 receptor expression in the rat bladder by bladder outlet obstruction. Urol Int. 2012;89:241–5.

    Article  CAS  PubMed  Google Scholar 

  19. Bschleipfer T, Nandigama R, Moeller S, Illig C, Weidner W, Kummer W. Bladder outlet obstruction influences mRNA expression of cholinergic receptors on sensory neurons in mice. Life Sci. 2012;91:1077–81.

    Article  CAS  PubMed  Google Scholar 

  20. Ochodnicky P, Cruz CD, Yoshimura N, Michel MC. Nerve growth factor in bladder dysfunction: contributing factor, biomarker, and therapeutic target. Neurourol Urodyn. 2011;30:1227–41.

    CAS  PubMed  Google Scholar 

  21. Imamura M, Kanematsu A, Yamamoto S, et al. Basic fibroblast growth factor modulates proliferation and collagen expression in urinary bladder smooth muscle cells. Am J Physiol Renal Physiol. 2007;293:F1007–17.

    Article  CAS  PubMed  Google Scholar 

  22. Bayliss M, Wu C, Newgreen D, Mundy AR, Fry CH. A quantitative study of atropine-resistant contractile responses in human detrusor smooth muscle, from stable, unstable and obstructed bladders. J Urol. 1999;162:1833–9.

    Article  CAS  PubMed  Google Scholar 

  23. Burmeister D, AbouShwareb T, D’Agostino Jr R, Andersson KE, Christ GJ. Impact of partial urethral obstruction on bladder function: time-dependent changes and functional correlates of altered expression of Ca(2)(+) signaling regulators. Am J Physiol Renal Physiol. 2012;302:F1517–28.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  24. Wibberley A, Chen Z, Hu E, Hieble JP, Westfall TD. Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle. Br J Pharmacol. 2003;138:757–66.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  25. Brading AF. A myogenic basis for the overactive bladder. Urology. 1997;50:57–67; discussion 8–73.

    Article  CAS  PubMed  Google Scholar 

  26. Imamura M, Negoro H, Kanematsu A, et al. Basic fibroblast growth factor causes urinary bladder overactivity through gap junction generation in the smooth muscle. Am J Physiol Renal Physiol. 2009;297:F46–54.

    Article  CAS  PubMed  Google Scholar 

  27. Drake MJ, Hedlund P, Harvey IJ, Pandita RK, Andersson KE, Gillespie JI. Partial outlet obstruction enhances modular autonomous activity in the isolated rat bladder. J Urol. 2003;170:276–9.

    Article  PubMed  Google Scholar 

  28. Oelke M, Kirschner-Hermanns R, Thiruchelvam N, Heesakkers J. Can we identify men who will have complications from benign prostatic obstruction (BPO)? ICI-RS 2011. Neurourol Urodyn. 2012;31:322–6.

    Article  PubMed  Google Scholar 

  29. McNeal JE. Anatomy of the prostate and morphogenesis of BPH. Prog Clin Biol Res. 1984;145:27–53.

    CAS  PubMed  Google Scholar 

  30. Girman CJ. Natural history and epidemiology of benign prostatic hyperplasia: relationship among urologic measures. Urology. 1998;51:8–12.

    Article  CAS  PubMed  Google Scholar 

  31. Rhodes T, Girman CJ, Jacobsen SJ, Roberts RO, Guess HA, Lieber MM. Longitudinal prostate growth rates during 5 years in randomly selected community men 40 to 79 years old. J Urol. 1999;161:1174–9.

    Article  CAS  PubMed  Google Scholar 

  32. Girman CJ, Jacobsen SJ, Rhodes T, Guess HA, Roberts RO, Lieber MM. Association of health-related quality of life and benign prostatic enlargement. Eur Urol. 1999;35:277–84.

    Article  CAS  PubMed  Google Scholar 

  33. Roehrborn CG. Male lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). Med Clin North Am. 2011;95:87–100.

    Article  PubMed  Google Scholar 

  34. Roehrborn CG. The utility of serum prostatic-specific antigen in the management of men with benign prostatic hyperplasia. Int J Impot Res. 2008;20 Suppl 3:S19–26.

    Article  PubMed  Google Scholar 

  35. Roehrborn CG. BPH progression: concept and key learning from MTOPS, ALTESS, COMBAT, and ALF-ONE. BJU Int. 2008;101 Suppl 3:17–21.

    Article  PubMed  Google Scholar 

  36. Bohnen AM, Groeneveld FP, Bosch JL. Serum prostate-specific antigen as a predictor of prostate volume in the community: the Krimpen study. Eur Urol. 2007;51:1645–52; discussion 52–3.

    Article  PubMed  Google Scholar 

  37. Berry SJ, Coffey DS, Walsh PC, Ewing LL. The development of human benign prostatic hyperplasia with age. J Urol. 1984;132:474–9.

    CAS  PubMed  Google Scholar 

  38. Shapiro E, Hartanto V, Lepor H. Anti-desmin vs. anti-actin for quantifying the area density of prostate smooth muscle. Prostate. 1992;20:259–67.

    Article  CAS  PubMed  Google Scholar 

  39. Schroder FH. Medical treatment of benign prostatic hyperplasia: the effect of surgical or medical castration. Prog Clin Biol Res. 1994;386:191–6.

    CAS  PubMed  Google Scholar 

  40. Donnell RF. Benign prostate hyperplasia: a review of the year’s progress from bench to clinic. Curr Opin Urol. 2011;21:22–6.

    Article  PubMed  Google Scholar 

  41. Reynard JM, Yang Q, Donovan JL, et al. The ICS-‘BPH’ Study: uroflowmetry, lower urinary tract symptoms and bladder outlet obstruction. Br J Urol. 1998;82:619–23.

    Article  CAS  PubMed  Google Scholar 

  42. Siroky MB, Olsson CA, Krane RJ. The flow rate nomogram: I. Development. J Urol. 1979;122:665–8.

    CAS  PubMed  Google Scholar 

  43. Siroky MB, Olsson CA, Krane RJ. The flow rate nomogram: II. Clinical correlation. J Urol. 1980;123:208–10.

    CAS  PubMed  Google Scholar 

  44. Haylen BT, Ashby D, Sutherst JR, Frazer MI, West CR. Maximum and average urine flow rates in normal male and female populations—the Liverpool nomograms. Br J Urol. 1989;64:30–8.

    Article  CAS  PubMed  Google Scholar 

  45. Chancellor MB, Blaivas JG, Kaplan SA, Axelrod S. Bladder outlet obstruction versus impaired detrusor contractility: the role of outflow. J Urol. 1991;145:810–2.

    CAS  PubMed  Google Scholar 

  46. Abrams P. Urodynamics. 3rd ed. London: Springer; 2006.

    Google Scholar 

  47. Abrams PH, Griffiths DJ. The assessment of prostatic obstruction from urodynamic measurements and from residual urine. Br J Urol. 1979;51:129–34.

    Article  CAS  PubMed  Google Scholar 

  48. Schafer W. Analysis of bladder-outlet function with the linearized passive urethral resistance relation, linPURR, and a disease-specific approach for grading obstruction: from complex to simple. World J Urol. 1995;13:47–58.

    Article  CAS  PubMed  Google Scholar 

  49. Abrams P. Bladder outlet obstruction index, bladder contractility index and bladder voiding efficiency: three simple indices to define bladder voiding function. BJU Int. 1999;84:14–5.

    Article  CAS  PubMed  Google Scholar 

  50. Bosch JL, Kranse R, van Mastrigt R, Schroder FH. Reasons for the weak correlation between prostate volume and urethral resistance parameters in patients with prostatism. J Urol. 1995;153:689–93.

    Article  CAS  PubMed  Google Scholar 

  51. Kaplan SA, Te AE, Pressler LB, Olsson CA. Transition zone index as a method of assessing benign prostatic hyperplasia: correlation with symptoms, urine flow and detrusor pressure. J Urol. 1995;154:1764–9.

    Article  CAS  PubMed  Google Scholar 

  52. Witjes WP, Aarnink RG, Ezz-el-Din K, Wijkstra H, Debruyne EM, de la Rosette JJ. The correlation between prostate volume, transition zone volume, transition zone index and clinical and urodynamic investigations in patients with lower urinary tract symptoms. Br J Urol. 1997;80:84–90.

    Article  CAS  PubMed  Google Scholar 

  53. Kojima M, Ochiai A, Naya Y, Ukimura O, Watanabe M, Watanabe H. Correlation of presumed circle area ratio with infravesical obstruction in men with lower urinary tract symptoms. Urology. 1997;50:548–55.

    Article  CAS  PubMed  Google Scholar 

  54. Chia SJ, Heng CT, Chan SP, Foo KT. Correlation of intravesical prostatic protrusion with bladder outlet obstruction. BJU Int. 2003;91:371–4.

    Article  CAS  PubMed  Google Scholar 

  55. Keqin Z, Zhishun X, Jing Z, Haixin W, Dongqing Z, Benkang S. Clinical significance of intravesical prostatic protrusion in patients with benign prostatic enlargement. Urology. 2007;70:1096–9.

    Article  PubMed  Google Scholar 

  56. Manieri C, Carter SS, Romano G, Trucchi A, Valenti M, Tubaro A. The diagnosis of bladder outlet obstruction in men by ultrasound measurement of bladder wall thickness. J Urol. 1998;159:761–5.

    Article  CAS  PubMed  Google Scholar 

  57. Kessler TM, Gerber R, Burkhard FC, Studer UE, Danuser H. Ultrasound assessment of detrusor thickness in men-can it predict bladder outlet obstruction and replace pressure flow study? J Urol. 2006;175:2170–3.

    Article  PubMed  Google Scholar 

  58. Kojima M, Inui E, Ochiai A, Naya Y, Ukimura O, Watanabe H. Noninvasive quantitative estimation of infravesical obstruction using ultrasonic measurement of bladder weight. J Urol. 1997;157:476–9.

    Article  CAS  PubMed  Google Scholar 

  59. Hakenberg OW, Linne C, Manseck A, Wirth MP. Bladder wall thickness in normal adults and men with mild lower urinary tract symptoms and benign prostatic enlargement. Neurourol Urodyn. 2000;19:585–93.

    Article  CAS  PubMed  Google Scholar 

  60. Wada N, Watanabe M, Kita M, Matsumoto S, Kakizaki H. Analysis of bladder vascular resistance before and after prostatic surgery in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction. Neurourol Urodyn. 2012;31:659–63.

    Article  PubMed  Google Scholar 

  61. McIntosh SL, Drinnan MJ, Griffiths CJ, Robson WA, Ramsden PD, Pickard RS. Noninvasive assessment of bladder contractility in men. J Urol. 2004;172:1394–8.

    Article  PubMed  Google Scholar 

  62. Griffiths CJ, Harding C, Blake C, et al. A nomogram to classify men with lower urinary tract symptoms using urine flow and noninvasive measurement of bladder pressure. J Urol. 2005;174:1323–6; discussion 6; author reply 6.

    Article  CAS  PubMed  Google Scholar 

  63. Harding C, Robson W, Drinnan M, et al. Predicting the outcome of prostatectomy using noninvasive bladder pressure and urine flow measurements. Eur Urol. 2007;52:186–92.

    Article  PubMed  Google Scholar 

  64. Pel JJ, van Mastrigt R. Non-invasive measurement of bladder pressure using an external catheter. Neurourol Urodyn. 1999;18:455–69; discussion 69–75.

    Article  CAS  PubMed  Google Scholar 

  65. Chiou RK, Matamoros A, Anderson JC, Taylor RJ. Changing concepts of urethral stricture management. I: Assessment of urethral stricture disease. Nebr Med J. 1996;81:282–6.

    CAS  PubMed  Google Scholar 

  66. Mundy AR, Andrich DE. Urethral strictures. BJU Int. 2011;107(1):6–26.

    Article  PubMed  Google Scholar 

  67. Chapple C, Barbagli G, Jordan G, et al. Consensus statement on urethral trauma. BJU Int. 2004;93:1195–202.

    Article  CAS  PubMed  Google Scholar 

  68. Fenton AS, Morey AF, Aviles R, Garcia CR. Anterior urethral strictures: etiology and characteristics. Urology. 2005;65:1055–8.

    Article  PubMed  Google Scholar 

  69. Lumen N, Hoebeke P, Willemsen P, De Troyer B, Pieters R, Oosterlinck W. Etiology of urethral stricture disease in the 21st century. J Urol. 2009;182:983–7.

    Article  PubMed  Google Scholar 

  70. Singh M, Blandy JP. The pathology of urethral stricture. J Urol. 1976;115:673–6.

    CAS  PubMed  Google Scholar 

  71. Das S, Tunuguntla HS. Balanitis xerotica obliterans—a review. World J Urol. 2000;18:382–7.

    Article  CAS  PubMed  Google Scholar 

  72. McMillan A, Pakianathan M, Mao JH, Macintyre CC. Urethral stricture and urethritis in men in Scotland. Genitourin Med. 1994;70:403–5.

    CAS  PubMed Central  PubMed  Google Scholar 

  73. Santucci RA, Joyce GF, Wise M. Male urethral stricture disease. J Urol. 2007;177:1667–74.

    Article  PubMed  Google Scholar 

  74. Mundy AR. Management of urethral strictures. Postgrad Med J. 2006;82:489–93.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  75. De Sy WA, Oosterlinck W. Treatment of stricture of the male urethra. Acta Urol Belg. 1981;49:93–250.

    PubMed  Google Scholar 

  76. Barbagli G, Guazzoni G, Lazzeri M. One-stage bulbar urethroplasty: retrospective analysis of the results in 375 patients. Eur Urol. 2008;53:828–33.

    Article  PubMed  Google Scholar 

  77. Andrich DE, Greenwell TJ, Mundy AR. The problems of penile urethroplasty with particular reference to 2-stage reconstructions. J Urol. 2003;170:87–9.

    Article  CAS  PubMed  Google Scholar 

  78. Elliott SP, Metro MJ, McAninch JW. Long-term followup of the ventrally placed buccal mucosa onlay graft in bulbar urethral reconstruction. J Urol. 2003;169:1754–7.

    Article  PubMed  Google Scholar 

  79. Santucci RA, Mario LA, McAninch JW. Anastomotic urethroplasty for bulbar urethral stricture: analysis of 168 patients. J Urol. 2002;167:1715–9.

    Article  PubMed  Google Scholar 

  80. Arlen AM, Powell CR, Hoffman HT, Kreder KJ. Buccal mucosal graft urethroplasty in the treatment of urethral strictures: experience using the two-surgeon technique. Scientific World Journal. 2010;10:74–9.

    Article  PubMed  Google Scholar 

  81. O’Riordan A, Narahari R, Kumar V, Pickard R. Outcome of dorsal buccal graft urethroplasty for recurrent bulbar urethral strictures. BJU Int. 2008;102:1148–51.

    Article  PubMed  Google Scholar 

  82. Elliott SP, Eisenberg ML, McAninch JW. First-stage urethroplasty: utility in the modern era. Urology. 2008;71:889–92.

    Article  PubMed  Google Scholar 

  83. Berglund RK, Angermeier KW. Combined buccal mucosa graft and genital skin flap for reconstruction of extensive anterior urethral strictures. Urology. 2006;68:707–10; discussion 10.

    Article  PubMed  Google Scholar 

  84. Santucci RA, McAninch JW, Mario LA, et al. Urethroplasty in patients older than 65 years: indications, results, outcomes and suggested treatment modifications. J Urol. 2004;172:201–3.

    Article  PubMed  Google Scholar 

  85. Barbagli G, De Angelis M, Romano G, Lazzeri M. Long-term followup of bulbar end-to-end anastomosis: a retrospective analysis of 153 patients in a single center experience. J Urol. 2007;178:2470–3.

    Article  PubMed  Google Scholar 

  86. Kellner DS, Fracchia JA, Armenakas NA. Ventral onlay buccal mucosal grafts for anterior urethral strictures: long-term followup. J Urol. 2004;171:726–9.

    Article  PubMed  Google Scholar 

  87. Pansadoro V, Emiliozzi P, Gaffi M, Scarpone P, DePaula F, Pizzo M. Buccal mucosa urethroplasty in the treatment of bulbar urethral strictures. Urology. 2003;61:1008–10.

    Article  PubMed  Google Scholar 

  88. Meneghini A, Cacciola A, Cavarretta L, Abatangelo G, Ferrarrese P, Tasca A. Bulbar urethral stricture repair with buccal mucosa graft urethroplasty. Eur Urol. 2001;39:264–7.

    Article  CAS  PubMed  Google Scholar 

  89. Mundy AR, Andrich DE. Posterior urethral complications of the treatment of prostate cancer. BJU Int. 2012;110(3):304–25.

    Article  PubMed  Google Scholar 

  90. Baskin LS, McAninch JW. Childhood urethral injuries: perspectives on outcome and treatment. Br J Urol. 1993;72:241–6.

    Article  CAS  PubMed  Google Scholar 

  91. Steenkamp JW, Heyns CF, de Kock ML. Internal urethrotomy versus dilation as treatment for male urethral strictures: a prospective, randomized comparison. J Urol. 1997;157(1):98–101.

    Article  CAS  PubMed  Google Scholar 

  92. Ahmed A, Kalayi GD. Urethral stricture at Ahmadu Bello University Teaching Hospital, Zaria. East Afr Med J. 1998;75:582–5.

    CAS  PubMed  Google Scholar 

  93. Fall B, Sow Y, Mansouri I, et al. Etiology and current clinical characteristics of male urethral stricture disease: experience from a public teaching hospital in Senegal. Int Urol Nephrol. 2011;43:969–74.

    Article  PubMed  Google Scholar 

  94. Tijani KH, Adesanya AA, Ogo CN. The new pattern of urethral stricture disease in Lagos, Nigeria. Niger Postgrad Med J. 2009;16:162–5.

    CAS  PubMed  Google Scholar 

  95. Dubey D, Kumar A, Bansal P, et al. Substitution urethroplasty for anterior urethral strictures: a critical appraisal of various techniques. BJU Int. 2003;91:215–8.

    Article  CAS  PubMed  Google Scholar 

  96. Cavalcanti AG, Yucel S, Deng DY, McAninch JW, Baskin LS. The distribution of neuronal and inducible nitric oxide synthase in urethral stricture formation. J Urol. 2004;171:1943–7.

    Article  CAS  PubMed  Google Scholar 

  97. Cavalcanti AG, Costa WS, Baskin LS, McAninch JA, Sampaio FJ. A morphometric analysis of bulbar urethral strictures. BJU Int. 2007;100:397–402.

    Article  PubMed  Google Scholar 

  98. Baskin LS, Constantinescu SC, Howard PS, et al. Biochemical characterization and quantitation of the collagenous components of urethral stricture tissue. J Urol. 1993;150:642–7.

    CAS  PubMed  Google Scholar 

  99. Meffert JJ, Davis BM, Grimwood RE. Lichen sclerosus. J Am Acad Dermatol. 1995;32:393–416; quiz 7-8.

    Article  CAS  PubMed  Google Scholar 

  100. Nuss GR, Granieri MA, Zhao LC, Thum DJ, Gonzalez CM. Presenting symptoms of anterior urethral stricture disease: a disease specific, patient reported questionnaire to measure outcomes. J Urol. 2012;187:559–62.

    Article  PubMed  Google Scholar 

  101. Waxman SW, Morey AF. Management of urethral strictures. Lancet. 2006;367(9520):1379–80.

    Article  PubMed  Google Scholar 

  102. Pain JA, Collier DG. Factors influencing recurrence of urethral strictures after endoscopic urethrotomy: the role of infection and peri-operative antibiotics. Br J Urol. 1984;56(2):217–9.

    Article  CAS  PubMed  Google Scholar 

  103. Fowler Jr FJ, Barry MJ, Lu-Yao G, Roman A, Wasson J, Wennberg JE. Patient-reported complications and follow-up treatment after radical prostatectomy. The National Medicare Experience: 1988-1990 (updated June 1993). Urology. 1993;42:622–9.

    Article  PubMed  Google Scholar 

  104. Hu JC, Gold KF, Pashos CL, Mehta SS, Litwin MS. Temporal trends in radical prostatectomy complications from 1991 to 1998. J Urol. 2003;169:1443–8.

    Article  PubMed  Google Scholar 

  105. Williams SB, Prasad SM, Weinberg AC, et al. Trends in the care of radical prostatectomy in the United States from 2003 to 2006. BJU Int. 2011;108:49–55.

    Article  PubMed  Google Scholar 

  106. Breyer BN, Davis CB, Cowan JE, Kane CJ, Carroll PR. Incidence of bladder neck contracture after robot-assisted laparoscopic and open radical prostatectomy. BJU Int. 2010;106:1734–8.

    Article  PubMed Central  PubMed  Google Scholar 

  107. Merrick GS, Butler WM, Wallner KE. Risk factors for the development of prostate brachytherapy related urethral strictures. J Urol. 2006;175:1376–81.

    Article  PubMed  Google Scholar 

  108. Elliott SP, McAninch JW, Chi T, Doyle SM, Master VA. Management of severe urethral complications of prostate cancer therapy. J Urol. 2006;176:2508–13.

    Article  PubMed  Google Scholar 

  109. Elliott SP, Meng MV, Elkin EP, et al. Incidence of urethral stricture after primary treatment for prostate cancer: data from CaPSURE. J Urol. 2007;178:529–34.

    Article  PubMed  Google Scholar 

  110. Sullivan L, Williams SG, Tai KH, Foroudi F, Cleeve L, Duchesne GM. Urethral stricture following high dose rate brachytherapy for prostate cancer. Radiother Oncol. 2009;91:232–6.

    Article  PubMed  Google Scholar 

  111. Besarani D, Amoroso P, Kirby R. Bladder neck contracture after radical retropubic prostatectomy. BJU Int. 2004;94:1245–7.

    Article  PubMed  Google Scholar 

  112. Augustin H, Pummer K, Daghofer F, Habermann H, Primus G, Hubmer G. Patient self-reporting questionnaire on urological morbidity and bother after radical retropubic prostatectomy. Eur Urol. 2002;42:112–7.

    Article  PubMed  Google Scholar 

  113. Giannarini G, Manassero F, Mogorovich A, et al. Cold-knife incision of anastomotic strictures after radical retropubic prostatectomy with bladder neck preservation: efficacy and impact on urinary continence status. Eur Urol. 2008;54:647–56.

    Article  PubMed  Google Scholar 

  114. Anger JT, Raj GV, Delvecchio FC, Webster GD. Anastomotic contracture and incontinence after radical prostatectomy: a graded approach to management. J Urol. 2005;173:1143–6.

    Article  PubMed  Google Scholar 

  115. Borboroglu PG, Sands JP, Roberts JL, Amling CL. Risk factors for vesicourethral anastomotic stricture after radical prostatectomy. Urology. 2000;56:96–100.

    Article  CAS  PubMed  Google Scholar 

  116. Theodoros C, Katsifotis C, Stournaras P, Moutzouris G, Katsoulis A, Floratos D. Abdomino-perineal repair of recurrent and complex bladder neck-prostatic urethra contractures. Eur Urol. 2000;38:734–40; discusssion 40-1.

    Article  CAS  PubMed  Google Scholar 

  117. Simonato A, Gregori A, Lissiani A, Carmignani G. Two-stage transperineal management of posterior urethral strictures or bladder neck contractures associated with urinary incontinence after prostate surgery and endoscopic treatment failures. Eur Urol. 2007;52:1499–504.

    Article  PubMed  Google Scholar 

  118. Okeke LI, Takure AO, Adebayo SA, Oluyemi OY, Oyelekan AA. Urethral obstruction from dislodged bladder diverticulum stones: a case report. BMC Urol. 2012;12:31.

    Article  PubMed Central  PubMed  Google Scholar 

  119. Appeadu-Mensah W, Hesse AA, Yaw MB. Giant bladder diverticulum: a rare cause of bladder outlet obstruction in children. Afr J Paediatr Surg. 2012;9:83–7.

    Article  PubMed  Google Scholar 

  120. Lang E, Cline K, Earhart V. Sliding ureterocele and bladder outlet obstruction. J Urol. 2005;173:601.

    Article  PubMed  Google Scholar 

  121. Krishnan A, de Souza A, Konijeti R, Baskin LS. The anatomy and embryology of posterior urethral valves. J Urol. 2006;175:1214–20.

    Article  PubMed  Google Scholar 

  122. Adorisio O, Bassani F, Silveri M. Cobb’s collar: a rare cause of urinary retention. BMJ Case Rep. 2013.

    Google Scholar 

  123. Parsons BA, Evans S, Wright MP. Prostate cancer and urinary incontinence. Maturitas. 2009;63:323–8.

    Article  PubMed  Google Scholar 

  124. Fleischmann JD, Catalona WJ. Endocrine therapy for bladder outlet obstruction from carcinoma of the prostate. J Urol. 1985;134:498–500.

    CAS  PubMed  Google Scholar 

  125. Mazur AW, Thompson IM. Efficacy and morbidity of “channel” TURP. Urology. 1991;38:526–8.

    Article  CAS  PubMed  Google Scholar 

  126. Crain DS, Amling CL, Kane CJ. Palliative transurethral prostate resection for bladder outlet obstruction in patients with locally advanced prostate cancer. J Urol. 2004;171:668–71.

    Article  PubMed  Google Scholar 

  127. Gnanapragasam VJ, Kumar V, Langton D, Pickard RS, Leung HY. Outcome of transurethral prostatectomy for the palliative management of lower urinary tract symptoms in men with prostate cancer. Int J Urol. 2006;13:711–5.

    PubMed  Google Scholar 

  128. Kollmeier MA, Stock RG, Cesaretti J, Stone NN. Urinary morbidity and incontinence following transurethral resection of the prostate after brachytherapy. J Urol. 2005;173:808–12.

    Article  CAS  PubMed  Google Scholar 

  129. Fowler Jr FJ, Barry MJ, Lu-Yao G, Wasson JH, Bin L. Outcomes of external-beam radiation therapy for prostate cancer: a study of Medicare beneficiaries in three surveillance, epidemiology, and end results areas. J Clin Oncol. 1996;14:2258–65.

    PubMed  Google Scholar 

  130. Crane C, Santucci RA. Surgical treatment of post-traumatic distraction posterior urethral strictures. Arch Esp Urol. 2011;64:219–26.

    CAS  PubMed  Google Scholar 

  131. Colapinto V, McCallum RW. Injury to the male posterior urethra in fractured pelvis: a new classification. J Urol. 1977;118:575–80.

    CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Medicine, Frenchay Hospital, Bristol, Avon, UK

    Thomas Renninson M.B.Ch.B.

  2. University of Bristol and Bristol Urological Institute, Bristol, UK

    Marcus J. Drake M.A. (Cantab), D.M. (Oxon.), F.R.C.S. (Urol.)

  3. Department of Urology, Cheltenham General Hospital, Cheltenham, Gloucestershire, GL53 7AN, UK

    Brian Andrew Parsons B.Sc., M.B.Ch.B., M.R.C.S.

Authors
  1. Thomas Renninson M.B.Ch.B.
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  2. Marcus J. Drake M.A. (Cantab), D.M. (Oxon.), F.R.C.S. (Urol.)
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  3. Brian Andrew Parsons B.Sc., M.B.Ch.B., M.R.C.S.
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Corresponding author

Correspondence to Brian Andrew Parsons B.Sc., M.B.Ch.B., M.R.C.S. .

Editor information

Editors and Affiliations

  1. Perelman School of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA

    Alan J. Wein

  2. Aarhus University, AIAS, Aarhus Institute of Advanced Studies, Aarhus, Denmark

    Karl-Erik Andersson

  3. Urological Institute, University of Bristol and Bristol, Bristol, United Kingdom

    Marcus J. Drake

  4. Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA

    Roger R. Dmochowski

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Renninson, T., Drake, M.J., Parsons, B.A. (2014). Dysfunction in Anatomic Outlet Obstruction in Men. In: Wein, A., Andersson, KE., Drake, M., Dmochowski, R. (eds) Bladder Dysfunction in the Adult. Current Clinical Urology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-0853-0_4

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  • DOI: https://doi.org/10.1007/978-1-4939-0853-0_4

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