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Next Generation Sequencing Technologies and Challenges in Sequence Assembly pp 3–13Cite as

Basics of Molecular Biology for Next-Generation Sequencing

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Part of the book series: SpringerBriefs in Systems Biology ((BRIEFSBIOSYS,volume 7))

Abstract

Organisms can be divided into simple (or unicellular) organisms and complex (or multicellular) organisms. Both simple and complex organisms share major cellular and biological processes that are mediated through proteins and nucleic acids. Proteins are the molecules responsible for every structural or biological process achieved inside living cells or living organisms, while nucleic acids encode the necessary information required for the building and regulation of proteins. In this chapter, we present some basics of molecular biology to provide readers without a biological background with an adequate introduction to the subject. These basics would greatly aid a lay audience in understanding this and other computational biology resources and textbooks. Readers with a firm biological background may choose to skip this chapter.

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Authors and Affiliations

  1. Department of Computer Science, Mansoura University, Mansoura, Egypt

    Sara El-Metwally & Osama M. Ouda

  2. Department of Information Technology, Michigan State University (MSU), East Lansing, MI, USA

    Osama M. Ouda

  3. Botany Department and Biotechnology Department, Al-Azhar University, Cairo, Egypt

    Mohamed Helmy

  4. The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto (UofT), Toronto, Canada

    Mohamed Helmy

Authors
  1. Sara El-Metwally
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  2. Osama M. Ouda
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  3. Mohamed Helmy
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El-Metwally, S., Ouda, O.M., Helmy, M. (2014). Basics of Molecular Biology for Next-Generation Sequencing. In: Next Generation Sequencing Technologies and Challenges in Sequence Assembly. SpringerBriefs in Systems Biology, vol 7. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0715-1_1

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