Skip to main content

The Problem of Whiplash Injuries: Aetiology, Assessment and Treatment

  • Chapter
  • First Online:
Handbook of Musculoskeletal Pain and Disability Disorders in the Workplace

Abstract

A large number of people are involved in a survivable road traffic crash (RTC) each year. While the health burden of major injuries, such as spinal cord and brain injuries, is clearly recognised, the physical and mental health outcomes of RTC survivors with predominantly non-hospitalised injuries are also surprisingly poor. Whiplash associated disorders (WAD) are the most common non-hospitalised RTC injury, and up to 50 % of people who experience a whiplash injury will never fully recover, and approximately 30 % will remain moderately to severely disabled by their condition (Carroll et al., 2008; Rebbeck, Sindhausen, & Cameron, 2006; Sterling, Jull, & Kenardy, 2006). Less recognised are the mental health issues that accompany this condition. The prevalence of psychiatric disorders has been shown to be 25 % for post-traumatic stress disorder (PTSD) (Kenardy, Heron-Delaney, Bellamy, Sterling, & Connelly, 2011; Mayou & Bryant, 2002; Sterling, Hendrikz, & Kenardy, 2010), 31 % for major depressive episode and 20 % for generalised anxiety disorder (Heron-Delaney, Kenardy, Bellamy, Sterling, & Connelly, 2011). Moreover, whiplash incurs enormous personal, social and economic costs. In Queensland, Australia, the economic costs related to whiplash injury are substantial, and exceeded $400 million from 2002 to 2009, with the condition accounting for the vast majority of any submitted claims, as well as the greatest incurred costs in the Queensland compulsory third-party insurance scheme (MAIC, 2010). Claims for personal injury after whiplash cost the United Kingdom more than £3 billion per year (Joslin, Khan, & Bannister, 2004), while data from the United States are even greater, with costs reaching $230 billion US dollars per annum (Blincoe et al., 2002).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Asmundson, G., Coons, M., Taylor, S., & Katz, J. (2002). PTSD and the experience of pain: Research and clinical implications. Canadian Journal of Psychiatry, 47(10), 930–937.

    Google Scholar 

  • Ayesh, E., Jensen, T., & Svensson, P. (2007). Hyper-sensitivity to mechanical and intra-articular electrical stimuli in persons with painful temporomandibular joints. Journal of Dental Research, 86(12), 1187–1192.

    Google Scholar 

  • Bajaj, P., Bajaj, P., Graven-Nielsen, T., & Arendt-Nielsen, L. (2001). Osteoarthritis and its association with muscle hyperalgesia: An experimental controlled study. Pain, 93(2), 107–114.

    PubMed  Google Scholar 

  • Banic, B., Petersen-Felix, S., Andersen, O., Radanov, B., Villiger, P., Arendt-Nielsen, L., et al. (2004). Evidence for spinal cord hypersensitivity in chronic pain after whiplash injury and in fibromyalgia. Pain, 107(1–2), 7–15.

    PubMed  Google Scholar 

  • Barnsley, L., Lord, S., & Bogduk, N. (1994). Clinical review. Whiplash injury. Pain, 58, 283–307.

    PubMed  Google Scholar 

  • Blincoe, L., Seay, A., Zaloshnja, E., Miller, T., Romano, E., Luchter, S., et al. (2002). Economic impact of motor vehicle crashes 2000 (DOT) (pp. 1–94). Washington, DC: National Highway Traffic Safety Administration.

    Google Scholar 

  • Buitenhuis, J., DeJong, J., Jaspers, J., & Groothoff, J. (2006). Relationship between posttraumatic stress disorder symptoms and the course of whiplash complaints. Journal of Psychosomatic Research, 61(3), 681–689.

    PubMed  Google Scholar 

  • Cameron, P., & Gabbe, B. (2009). Editorial: The effect of compensation claims on outcomes after injury. Injury, 40, 905–906.

    PubMed  Google Scholar 

  • Carroll, L., Connelly, L., Spearing, N., Cote, P., Buitenhuis, J., & Kenardy, J. (2011). Complexities in understanding the role of compensation related factors on recovery from whiplash associated disorders. Spine, 36(25S), S316–S321.

    PubMed  Google Scholar 

  • Carroll, L., Holm, L., Ferrari, R., Ozegovic, D., & Cassidy, D. (2009). Recovery in whiplash-associated disorders: Do you get what you expect. The Journal of Rheumatology, 36, 1063–1070.

    PubMed  Google Scholar 

  • Carroll, L., Holm, L., Hogg-Johnson, S., Cote, P., Cassidy, D., Haldeman, S., et al. (2008). Course and prognostic factors for neck pain in whiplash-associated disorders (WAD). Results of the bone and joint decade 2000–2010 task force on neck pain and its associated disorders. Spine, 33(42), 583–592.

    Google Scholar 

  • Carroll, L., Liu, Y., Holm, L., Cassidy, D., & Cote, P. (2011). Pain-related emotions in early stages of recovery in whiplash-associated disorders: Their presence, intensity and association with pain recovery. Psychosomatic Medicine, 73(8), 708–715.

    PubMed  Google Scholar 

  • Chen, J., Lipska, B., & Halim, N. (2004). Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): Effects on mRNA, protein, and enzyme activity in postmortem human brain. American Journal of Human Genetics, 75, 807–821.

    PubMed Central  PubMed  Google Scholar 

  • Chien, A., Eliav, E., & Sterling, M. (2008). Whiplash (Grade II) and cervical radiculopathy share a similar sensory presentation: An investigation using quantitative sensory testing. Clinical Journal of Pain, 24(7), 595–603.

    PubMed  Google Scholar 

  • Chien, A., Eliav, E., & Sterling, M. (2009). Hypoaesthesia occurs with sensory hypersensitivity in chronic whiplash: Indication of a minor peripheral neuropathy? Manual Therapy, 14, 137–145.

    Google Scholar 

  • Chien, A., Eliav, E., & Sterling, M. (2010). Sensory hypoaesthesia is a feature of chronic whiplash but not chronic idiopathic neck pain. Manual Therapy, 15(1), 48–53.

    PubMed  Google Scholar 

  • Connelly, L., & Spearing, N. (2011). Compensation and health outcomes. In M. Sterling & J. Kenardy (Eds.), Whiplash: Evidence base for clinical practice. Chatswood, NSW: Elsevier.

    Google Scholar 

  • Coombes, B., Bisset, L., & Vicenzino, B. (2012). Thermal hyperalgesia distinguishes those with severe pain and disability in unilateral lateral epicondylalgia. Clinical Journal of Pain, 28(7), 595–601.

    PubMed  Google Scholar 

  • Cote, P., Hogg-Johnson, S., Cassidy, J. D., Carroll, L., Frank, J. W., & Bombardier, C. (2007). Early aggressive care and delayed recovery form whiplash: Isolated finding or reproducible result? Arthritis and Rheumatism, 57(5), 861–868.

    PubMed  Google Scholar 

  • Curatolo, M., Arendt-Nielsen, L., & Petersen-Felix, S. (2004). Evidence, mechanisms and clinical implications of central hypersensitivity in chronic pain after whiplash injury. Clinical Journal of Pain, 20(6), 469–476.

    PubMed  Google Scholar 

  • Curatolo, M., Arendt-Nielsen, L., & Petersen-Felix, S. (2006). Central hypersensitivity in chronic pain: Mechanisms and clinical implications. Physical Medicine & Rehabilitation Clinics of North America, 17, 287–302.

    Google Scholar 

  • Curatolo, M., Bogduk, N., Ivancic, P., McLean, S., Siegmund, G., & Winkelstein, B. (2011). The role of tissue damage in whiplash associated disorders. Spine, 36(25S), S309–S315.

    PubMed Central  PubMed  Google Scholar 

  • Curatolo, M., & Sterling, M. (2011). Pain-processing mechanisms in whiplash associated disorders. In M. Sterling & J. Kenardy (Eds.), Whiplash: Evidence-base for clinical practice. Australia: Elsevier.

    Google Scholar 

  • Dall’Alba, P., Sterling, M., Trealeven, J., Edwards, S., & Jull, G. (2001). Cervical range of motion discriminates between asymptomatic and whiplash subjects. Spine, 26(19), 2090–2094.

    PubMed  Google Scholar 

  • Diatchenko, L., Slade, G., Nackley, A., Bhalang, K., Sigurdsson, A., Belfer, I., et al. (2005). Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Human Molecular Genetics, 14, 135–143.

    PubMed  Google Scholar 

  • Dunne, R., Kenardy, J., & Sterling, M. (2012a). The impact of posttraumatic stress disorder on physiological arousal, disability and sensory pain thresholds in patients with chronic whiplash, under review.

    Google Scholar 

  • Dunne, R., Kenardy, J., & Sterling, M. (2012b). A randomised controlled trial of cognitive behavioural therapy for the treatment of PTSD in the context of chronic whiplash. Clinical Journal of Pain, 28(9), 755–765.

    Google Scholar 

  • Elbers, N., Hulst, L., Cuijpers, P., Akkermans, A., & Bruinvels, D. (2013). Do compensation processes impair mental health? A meta-analysis. Injury, 44(5), 674–683.

    PubMed  Google Scholar 

  • Elliott, J., Jull, G., Noteboom, T., Darnell, R., Galloway, G., & Gibbon, W. (2006). Fatty infiltration in the cervical extensor muscles in persistent whiplash associated disorders: An MRI analysis. Spine, 31(22), E847–E851.

    PubMed  Google Scholar 

  • Elliott, J., Jull, G., Sterling, M., Noteboom, T., Darnell, R., & Galloway, G. (2008). Fatty infiltrate in the cervical extensor muscles is not a feature of chronic insidious onset neck pain. Clinical Radiology, 63(6), 681–687.

    PubMed  Google Scholar 

  • Elliott, J., O’Leary, S., Sterling, M., Hendrikz, J., Pedler, A., & Jull, G. (2010). MRI findings of fatty infiltrate in the cervical flexors in chronic whiplash. Spine, 35(9), 948–954.

    PubMed  Google Scholar 

  • Elliott, J., Pedler, A., Kenardy, J., Galloway, G., Jull, G., & Sterling, M. (2011). The temporal development of fatty infiltrates in the neck muscles following whiplash injury: An association with pain and posttraumatic stress. PLOS ONE, 6(6), e21194.

    PubMed Central  PubMed  Google Scholar 

  • Falla, D., Jull, G., & Hodges, P. (2004). Neck pain patients demonstrate reduced EMG activity of the deep cervical flexor muscles during performance of the cranio-cervical flexion test. Spine, 29(19), 2108–2114.

    PubMed  Google Scholar 

  • Ferrari, R., Rowe, B., Majumdar, S., Cassidy, D., Blitz, S., Wright, S., et al. (2005). Simple educational intervention to improve the recovery from acute whiplash: Results of a randomized, controlled trial. Academic Emergency Medicine, 12(8), 699–706.

    PubMed  Google Scholar 

  • Foa, E., Riggs, D., Dancu, C., & Rothbaum, B. (1993). Reliability and validity of a brief instrument for assessing post-traumatic stress disorder. Journal of Traumatic Stress, 6(4), 459–473.

    Google Scholar 

  • Forbes, D., Creamer, M., Phelps, A., Couineau, A., Cooper, J., Bryant, R., et al. (2007). Treating adults with acute stress disorder and posttraumatic stress disorder in general practice: A clinical update. Medical Journal of Australia, 187(2), 120–123.

    PubMed  Google Scholar 

  • France, C., Rhudy, J., & McGlone, S. (2009). Using normalized EMG to define the nociceptive flexion reflex (NFR) threshold: Further evaluation of standardized NFR scoring criteria. Pain, 145(1–2), 211–218.

    PubMed  Google Scholar 

  • Gaab, J., Baumann, S., Budnoik, A., Gmunder, H., Hottinger, N., & Ehlert, U. (2005). Reduced reactivity and enhanced negative feedback sensitivity of the hypothalamus-pituitary-adrenal axis in chronic whiplash associated disorders. Pain, 119, 219–224.

    PubMed  Google Scholar 

  • George, S., Fritz, J., Bialosky, J., & Donald, D. (2003). The effect of a fear-avoidance-based physical therapy intervention for patients with acute low back pain: Results of a randomized clinical trial. Spine, 28, 2551–2560.

    PubMed  Google Scholar 

  • Goldsmith, R., Wright, C., Bell, S., & Rushton, A. (2012). Cold hyperalgesia as a prognostic factor in whiplash associated disorders: A systematic review. Manual Therapy, 17(5), 402–410.

    PubMed  Google Scholar 

  • Gottrup, H., Andersen, J., Arendt-Nielsen, L., & Jensen, T. (2000). Psychophysical examination in patients with post-mastectomy pain. Pain, 87(3), 275–284.

    PubMed  Google Scholar 

  • Haines, T., Gross, A., Burnie, S., Goldsmith, C., & Perry, J. (2009). Patient education for neck pain with or without radiculopathy. Cochrane Database of Systematic Reviews, (4), CD005106.

    Google Scholar 

  • Haldeman, S., Carroll, L., Cassidy, D., Schubert, J., & Nygren, A. (2008). The bone and joint decade 2000–2010 task force on neck pain and its associated disorders executive summary. Spine, 33(4s), S5–S7.

    PubMed  Google Scholar 

  • Heron-Delaney, M., Kenardy, J., Bellamy, N., Sterling, M., & Connelly, L. (2011). Adults’ adjustment to minor and moderate injuries following road traffic crashes: Wave 2 preliminary findings. Report to MAIC.

    Google Scholar 

  • Holm, L., Carroll, L., Cassidy, D., Skillgate, E., & Ahlbom, A. (2008). Expectations for recovery important in the prognosis of whiplash injuries. PLOS Medicine, 5(5), e105.

    PubMed Central  PubMed  Google Scholar 

  • Jaspers, J. (1998). Whiplash and post-traumatic stress disorder. Disability and Rehabilitation, 20, 397–404.

    PubMed  Google Scholar 

  • Joslin, C., Khan, S., & Bannister, G. (2004). Long-term disability after neck injury. A comparative study. Journal of Bone and Joint Surgery. British Volume, 86(7), 1032–1034.

    Google Scholar 

  • Jull, G. (2000). Deep cervical flexor muscle dysfunction in whiplash. Journal of Musculoskeletal Pain, 8(1/2), 143–154.

    Google Scholar 

  • Jull, G., Kristjansson, E., & Dall’Alba, P. (2004). Impairment in the cervical flexors: A comparison of whiplash and insidious onset neck pain patients. Manual Therapy, 9(2), 89–94.

    PubMed  Google Scholar 

  • Jull, G., Soderlund, A., Stemper, B., Kenardy, J., Gross, A., Cote, P., et al. (2011). Towards optimal early management after whiplash injury to lessen the rate of transition to chronicity. Spine, 36(25S), s275–s287.

    Google Scholar 

  • Jull, G., & Sterling, M. (2011). Whiplash injury recovery: A self management guide. http://www.maic.qld.gov.au/forms-publications-stats/pdfs/whiplash-injury-recovery-booklet.pdf

  • Jull, G., Sterling, M., Kenardy, J., & Beller, E. (2007). Does the presence of sensory hypersensitivity influence outcomes of physical rehabilitation for chronic whiplash?—A preliminary RCT. Pain, 129(2), 28–34.

    PubMed  Google Scholar 

  • Jull, G., Trott, P., Potter, H., Zito, G., Niere, K., Emberson, J., et al. (2002). A randomised controlled trial of physiotherapy management for cervicogenic headache. Spine, 27(17), 1835–1843.

    PubMed  Google Scholar 

  • Kamper, S., Rebbeck, T., Maher, C., McAuley, J., & Sterling, M. (2008). Course and prognostic factors of whiplash: A systematic review and meta-analysis. Pain, 138(3), 617–629.

    PubMed  Google Scholar 

  • Kasch, H., Qerama, E., Bach, F., & Jensen, T. (2005). Reduced cold pressor pain tolerance in non-recovered whiplash patients: A 1 year prospective study. European Journal of Pain, 9(5), 561–569.

    PubMed  Google Scholar 

  • Kasch, H., Qerama, E., Kongsted, A., Bendix, T., Jensen, T., & Bach, F. (2008). Clinical assessment of prognostic factors for long-term pain and handicap after whiplash injury: A 1-year prospective study. European Journal of Neurology, 15(11), 1222–1230.

    PubMed  Google Scholar 

  • Keefe, F., & Somers, T. (2010). Psychological approaches to understanding and treating arthritis pain. Nature Reviews. Rheumatology, 6, 210–216.

    PubMed  Google Scholar 

  • Kenardy, J., Heron-Delaney, M., Bellamy, N., Sterling, M., & Connelly, L. (2011). Adults’ adjustment to minor and moderate injuries following road traffic crashes: Wave 1 fundings. In Q. Report to MAIC (Ed.).

    Google Scholar 

  • Kenardy, J., & Sterling, M. (2008). Whiplash evidence based treatment resource. Accessed October 30, 2012. www.som.uq.edu.au/whiplash

  • Khwaja, S., Minnerop, M., & Singer, A. (2010). Comparison of ibuprofen, cyclobenzaprine or both in patients with acute cervical strain: A randomized controlled trial. Canadian Journal of Emergency Medicine, 12(1), 39–44.

    PubMed  Google Scholar 

  • Kongsted, A., Leboeuf-Yde, C., Korsholm, L., & Bendix, T. (2008). Are altered smooth pursuit eye movements related to chronic pain and disability following whiplash injuries? A prospective trial with one-year follow-up. Clinical Rehabilitation, 22, 469–479.

    PubMed  Google Scholar 

  • Kongsted, A., Qerama, E., Kasch, H., Bach, F., Korsholm, L., Jensen, T., et al. (2008). Education of patients after whiplash injury: Is oral advice any better than a pamphlet? Spine, 33(22), E843–E848.

    PubMed  Google Scholar 

  • Kuch, K., Cox, B. J., Evans, R., & Shulman, I. (1994). Phobias, panic, and pain in 55 survivors of road vehicle accidents. Journal of Anxiety Disorders, 8(2), 181–187.

    Google Scholar 

  • Lamb, S., Williams, M., Withers, E., Perry, J., Gates, S., Williamson, E., et al. (2009). A national survey of clinical practice for the management of whiplash-associated disorders in UK emergency departments. Emergency Medicine Journal, 26, 644–647.

    PubMed  Google Scholar 

  • Lewis, C., Souvlis, T., & Sterling, M. (2010). Sensory characteristics of tender points in the low back. Manual Therapy, 15, 451–456.

    PubMed  Google Scholar 

  • Lindstrom, R., Schomacher, J., Farina, D., Rechter, L., & Falla, D. (2011). Association between neck muscle coactivation, pain, and strength in women with neck pain. Manual Therapy, 16(1), 80–86.

    PubMed  Google Scholar 

  • Lord, S., Barnsley, L., Wallis, B., & Bogduk, N. (1996). Chronic cervical zygapophysial joint pain after whiplash: A placebo-controlled prevalence study… including commentary by Derby R Jr. Spine, 21(15), 1737–1745.

    PubMed  Google Scholar 

  • MAA. (2007). Guidelines for the management of whiplash associated disorders (p. 16). Sydney: Motor Accident Authority (NSW). www.maa.nsw.gov.au

  • MacDermid, J., Walton, D., Avery, S., Blanchard, A., Etruw, E., McAlpine, C., et al. (2009). Measurement properties of the Neck Disability Index: A systematic review. Journal of Orthopaedic & Sports Physical Therapy, 39(5), 400–417.

    Google Scholar 

  • Macintyre, P., Scott, D., Schug, S., Visser, E., & Walker, S. (2010). Acute pain management: Scientific evidence. Melbourne: ANZVA & FPM.

    Google Scholar 

  • MAIC. (2010). Annual report 2009–2010. Brisbane: MAIC.

    Google Scholar 

  • Maxwell, S., & Sterling, M. (2013). An investigation of the use of a numeric pain rating scale with ice application to the neck to determine cold hyperalgesia. Manual Therapy, 18(2), 172–174.

    PubMed  Google Scholar 

  • Mayou, R., & Bryant, B. (2002). Psychiatry of whiplash neck injury. British Journal of Psychiatry, 180, 441–448.

    PubMed  Google Scholar 

  • McCarthy, S. (2008). Posttraumatic stress diagnostic scale (PDS). Occupational Medicine, 58, 379.

    PubMed  Google Scholar 

  • McClune, T., Burton, A., & Waddell, G. (2002). Whiplash associated disorders: A review of the literature to guide patient information and advice. Emergency Medicine Journal, 19, 499–506.

    PubMed Central  PubMed  Google Scholar 

  • McFarlane, A. C., Ellis, N., Barton, C., Browne, D., & Van Hooff, M. (2008). The conundrum of medically unexplained symptoms: Questions to consider. Psychosomatics: Journal of Consultation Liaison Psychiatry, 48(5), 369–377. doi:10.1176/appi.psy.49.5.369.

    Google Scholar 

  • McLean, S. (2011). The potential contribution of stress systems to the transition to chronic whiplash associated disorders. Spine, 36(25S), S226–S232.

    PubMed Central  PubMed  Google Scholar 

  • McLean, S., Clauw, D., Abelson, J., & Liberzon, I. (2005). The development of persistent pain and psychological morbidity after motor vehicle collision: Integrating the potential role of stress response systems into a biopsychosocial model. Psychosomatic Medicine, 67, 783–790.

    PubMed  Google Scholar 

  • McLean, S., Diatchenko, L., Lee, M., Swor, R., Domeier, R., Jones, J., et al. (2011). Catechol O-methyltransferase haplotype predicts immediate musculoskeletal neck pain and psychological symptoms after motor vehicle collision. The Journal of Pain, 12, 101–107.

    PubMed  Google Scholar 

  • Nackley, A., Tan, K., Fecho, K., Flood, P., Diatchenko, L., & Maixner, W. (2007). Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors. Pain, 128(3), 199–208.

    PubMed  Google Scholar 

  • Nederhand, M., Hermens, H., Ijzerman, M., Turk, D., & Zilvold, G. (2002). Cervical muscle dysfunction in chronic whiplash associated disorder grade 2. The relevance of trauma. Spine, 27(10), 1056–1061.

    PubMed  Google Scholar 

  • NHMRC. (2007). Australian guidelines for the treatment of adults with ASD and PTSD. Canberra: NHMRC.

    Google Scholar 

  • O’Donnell, M., Creamer, M., Bryant, R., Schnyder, U., & Shalev, A. (2003). Posttraumatic disorders following injury: An empirical and methodological review. Clinical Psychology Review, 23, 587–603.

    PubMed  Google Scholar 

  • Oliveira, A., Gevirtz, R., & Hubbard, R. (2006). A psycho-educational video used in the emergency department provides effective treatment for whiplash injuries. Spine, 31(15), 1652–1657.

    PubMed  Google Scholar 

  • Pape, E., Hagen, K. B., Brox, J. I., Natvig, B., & Schirmer, H. (2009). Early multidisciplinary evaluation and advice was ineffective for whiplash-associated disorders. European Journal of Pain, 13, 1068–1075.

    PubMed  Google Scholar 

  • Passatore, M., & Roatta, S. (2006). Influence of sympathetic nervous system on sensorimotor function: Whiplash associated disorders (WAD) as a model. European Journal of Applied Physiology, 98(5), 423–449.

    PubMed  Google Scholar 

  • Pedler, A., & Sterling, M. (2011). Assessing fear-avoidance beliefs in patients with whiplash associated disorders: A comparison of 2 measures. Clinical Journal of Pain, 27(6), 502–507.

    PubMed  Google Scholar 

  • Pettersson, K., & Toolanen, G. (1998). High-dose methylprednisolone prevents extensive sick leave after whiplash injury. Spine, 23(9), 984–989.

    PubMed  Google Scholar 

  • Phillips, L., Carroll, L., Cassidy, D., & Cote, P. (2010). Whiplash-associated disorders: Who gets depressed? Who stays depressed? European Spine Journal, 19(6), 945–956.

    PubMed Central  PubMed  Google Scholar 

  • Provinciali, L., Baroni, M., Illuminati, L., & Ceravolo, M. (1996). Multimodal treatment to prevent the late whiplash syndrome. Scandinavian Journal of Rehabilitation Medicine, 28(2), 105–111.

    PubMed  Google Scholar 

  • Rebbeck, T., Sindhausen, D., & Cameron, I. (2006). A prospective cohort study of health outcomes following whiplash associated disorders in an Australian population. Injury Prevention, 12, 86–93.

    Google Scholar 

  • Ronnen, J., De Korte, P., & Brink, P. (1996). Acute whiplash injury: Is there a role for MR imaging. Radiology, 201, 93–96.

    Google Scholar 

  • Rosenfeld, M., Gunnarsson, R., & Borenstein, P. (2000). Early intervention in whiplash-associated disorders. A comparison of two protocols. Spine, 25, 1782–1787.

    PubMed  Google Scholar 

  • Rosenfeld, M., Seferiadis, A., Carllson, J., & Gunnarsson, R. (2003). Active intervention in patients with whiplash associated disorders improves long-term prognosis: A randomised controlled clinical trial. Spine, 28(22), 2491–2498.

    PubMed  Google Scholar 

  • Rosenfeld, M., Seferiadis, A., & Gunnarsson, R. (2006). Active involvement and intervention in patients exposed to whiplash trauma in automobile crashes reduces costs. Spine, 31(16), 1799–1804.

    PubMed  Google Scholar 

  • Rushton, A., & Wright, C. (2011). Physiotherapy rehabilitation for whiplash associated disorder II: A systematic review and meta-analysis of randomised controlled trials. BMJ Open, 1, e000265.

    PubMed Central  PubMed  Google Scholar 

  • Russell, G., & Nicol, P. (2009). ‘I’ve broken my neck or something!’ The general practice experience of whiplash. Family Practice, 26, 115–120.

    PubMed  Google Scholar 

  • Scholten-Peeters, G., Verhagen, A., Bekkering, G., van der Windt, D., Barnsley, L., Oostendorp, R., et al. (2003). Prognostic factors of whiplash associated disorders: A systematic review of prospective cohort studies. Pain, 104(1–2), 303–322.

    PubMed  Google Scholar 

  • Scott, W., & Sullivan, M. (2012). Perceived injustice moderates the relationship between pain and depressive symptoms among individuals with persistent musculoskeletal pain. Pain Research and Management, 17(5), 335–340.

    PubMed Central  PubMed  Google Scholar 

  • Soderlund, A., & Lindberg, P. (2001). Cognitive behavioural components in physiotherapy management of chronic whiplash associated disorders (WAD)—A randomised group study. Physiotherapy Theory and Practice, 17, 229–238.

    Google Scholar 

  • Spearing, N., Connelly, L., Gargett, S., & Sterling, M. (2012). Systematic review: Does compensation have a negative effect on health after whiplash? Pain, 153, 1274–1282.

    PubMed  Google Scholar 

  • Spitzer, W., Skovron, M., Salmi, L., Cassidy, J., Duranceau, J., Suissa, S., et al. (1995). Scientific Monograph of Quebec Task Force on whiplash associated disorders: Redefining “whiplash” and its management. Spine, 20(8S), 1–73.

    Google Scholar 

  • Staud, R. (2006). Biology and therapy of fibromyalgia: Pain in fibromyalgia syndrome. Arthritis Research and Therapy, 8, 208.

    PubMed Central  PubMed  Google Scholar 

  • Steinberg, E., Ovadia, D., Nissan, M., Menahem, A., & Dekel, S. (2005). Whiplash injury: Is there a role for electromyographic studies. Archives of Orthopaedic Trauma Surgery, 125(1), 46–50.

    Google Scholar 

  • Sterling, M. (2010). Differential development of sensory hypersensitivity and a measure of spinal cord hyperexcitability following whiplash injury. Pain, 150, 501–506.

    PubMed  Google Scholar 

  • Sterling, M., Carroll, L., Kasch, H., Kamper, S., & Stemper, B. (2011). Prognosis after whiplash injury: Where to from here? Discussion Paper 3. Spine, 36(25S), s330–s334.

    PubMed  Google Scholar 

  • Sterling, M., & Chadwick, B. (2010). Psychological processes in daily life with chronic whiplash: Relations of post-traumatic stress symptoms and fear-of-pain to hourly pain and uptime. Clinical Journal of Pain, 26(7), 573–582.

    PubMed  Google Scholar 

  • Sterling, M., Hendrikz, J., & Kenardy, J. (2010). Developmental trajectories of pain/disability and PTSD symptoms following whiplash injury. Pain, 150(1), 22–28.

    PubMed  Google Scholar 

  • Sterling, M., Hendrikz, J., & Kenardy, J. (2011). Similar factors predict disability and PTSD trajectories following whiplash injury. Pain, 152(6), 1272–1278.

    PubMed  Google Scholar 

  • Sterling, M., Hendrikz, J., Kenardy, J., Kristjansson, E., Dumas, J.-P., Niere, K., et al. (2012). Assessment and validation of prognostic models for poor functional recovery 12 months after whiplash injury: A multicentre inception cohort study. Pain, 153(8), 1727–1734.

    PubMed  Google Scholar 

  • Sterling, M., Jull, G., & Kenardy, J. (2006). Physical and psychological predictors of outcome following whiplash injury maintain predictive capacity at long term follow-up. Pain, 122, 102–108.

    PubMed  Google Scholar 

  • Sterling, M., Jull, G., Vicenzino, B., & Kenardy, J. (2003). Sensory hypersensitivity occurs soon after whiplash injury and is associated with poor recovery. Pain, 104, 509–517.

    PubMed  Google Scholar 

  • Sterling, M., Jull, G., Vicenzino, B., & Kenardy, J. (2004). Characterisation of acute whiplash associated disorders. Spine, 29(2), 182–188.

    PubMed  Google Scholar 

  • Sterling, M., Jull, G., Vicenzino, B., Kenardy, J., & Darnell, R. (2005). Physical and psychological factors predict outcome following whiplash injury. Pain, 114, 141–148.

    PubMed  Google Scholar 

  • Sterling, M., Jull, G., Vizenzino, B., Kenardy, J., & Darnell, R. (2003). Development of motor system dysfunction following whiplash injury. Pain, 103, 65–73.

    PubMed  Google Scholar 

  • Sterling, M., & Kenardy, J. (2006). The relationship between sensory and sympathetic nervous system changes and acute posttraumatic stress following whiplash injury—A prospective study. Journal of Psychosomatic Research, 60, 387–393.

    PubMed  Google Scholar 

  • Sterling, M., Kenardy, J., Jull, G., & Vicenzino, B. (2003). The development of psychological changes following whiplash injury. Pain, 106(3), 481–489.

    PubMed  Google Scholar 

  • Stone, A., & Sterling, M. (2009). Decreased heart rate variability in chronic whiplash is associated with pain, disability, stress and fear of movement but not cold allodynia. Paper presented at the Australian Physiotherapy Conference, Sydney.

    Google Scholar 

  • Stone, A., Vicenzino, B., Lim, E., & Sterling, M. (2013). Measures of central hyperexcitability in chronic whiplash associated disorder—A systematic review and meta-analysis. Manual Therapy, 18(2), 111–117.

    PubMed  Google Scholar 

  • Sullivan, M., Adams, H., Horan, S., Mahar, D., Boland, D., & Gross, R. (2008). The role of perceived injustice in the experience of chronic pain and disability: Scale development and validation. Journal of Occupational Rehabilitation, 18, 249–261.

    PubMed  Google Scholar 

  • Sullivan, M., Adams, H., Rhodenizer, T., & Stanish, W. (2006). A psychosocial risk factor—Targeted intervention for the prevention of chronic pain and disability following whiplash injury. Physical Therapy, 86(1), 8–18.

    PubMed  Google Scholar 

  • Sullivan, M., Thibault, P., Simmonds, M., Milioto, M., Cantin, A.-P., & Velly, A. (2009). Pain, perceived injustice and the persistence of post-traumatic stress symptoms during the course of rehabilitation for whiplash injuries. Pain, 145(3), 325–331.

    PubMed  Google Scholar 

  • Taylor, J., & Taylor, M. (1996). Cervical spinal injuries: An autopsy study of 109 blunt injuries. Journal of Musculoskeletal Pain, 4(4), 61–79.

    Google Scholar 

  • Tchivilera, I., Lim, P., Smith, S., Slade, G., Diatchenko, L., McLean, S., et al. (2010). Effect of COMT polymorphism on response to propranolol therapy in chronic musculoskeletal pain: A randomised, double-blind, placebo-controlled, crossover pilot. Pharmacogenetics and Genomics, 20(4), 239–248.

    Google Scholar 

  • Teasell, R., McClure, J., Walton, D., Pretty, J., Salter, K., Meyer, M., et al. (2010a). A research synthesis of therapeutic interventions for WAD: Part 4—Non invasive interventions for chronic WAD. Pain Research and Management, 15(5), 313–322.

    PubMed Central  PubMed  Google Scholar 

  • Teasell, R., McClure, J., Walton, D., Pretty, J., Salter, K., Meyer, M., et al. (2010b). A research synthesis of therapeutic interventions for whiplash-associated disorder (WAD): Part 2—Interventions for acute WAD. Pain Research and Management, 15(5), 295–304.

    PubMed Central  PubMed  Google Scholar 

  • TRACsa. (2008). A clinical pathway for best practice management of acute and chronic whiplash-associated disorders. Adelaide: South Australian Centre for Trauma and Injury Recovery.

    Google Scholar 

  • Treleaven, J. (2008). Sensorimotor disturbances in neck disorders affecting postural stability, head and eye movement control. Manual Therapy, 13(1), 2–11.

    PubMed  Google Scholar 

  • Treleaven, J., Jull, G., & Low choy, N. (2005). Standing balance in persistent whiplash: A comparison between subjects with and without dizziness. Journal of Rehabilitation Medicine, 37, 224–229.

    PubMed  Google Scholar 

  • Treleaven, J., Jull, G., & LowChoy, N. (2005). Smooth pursuit neck torsion test in whiplash associated disorders: Relationship to self-reports of neck pain and disability, dizziness and anxiety. Journal of Rehabilitation Medicine, 37, 219–223.

    PubMed  Google Scholar 

  • Treleaven, J., Jull, G., & Sterling, M. (2003). Dizziness and unsteadiness following whiplash injury—Characteristic features and relationship with cervical joint position error. Journal of Rehabilitation, 34, 1–8.

    Google Scholar 

  • Van Oosterwijck, J., Nijs, J., Meeus, M., & Paul, L. (2013). Evidence for central sensitization in chronic whiplash: A systematic literature review. European Journal of Pain, 17(3), 299–312.

    PubMed  Google Scholar 

  • Vendrig, A., van Akkerveeken, P., & McWhorter, K. (2000). Results of a multimodal treatment program for patients with chronic symptoms after a whiplash injury of the neck. Spine, 25, 238–244.

    PubMed  Google Scholar 

  • Walburn, J., Vedhara, K., Hankins, M., Rixon, L., & Weinman, J. (2009). Psychological stress and wound healing in humans: A systematic review and meta-analysis. Journal of Psychosomatic Research, 67, 253–271.

    PubMed  Google Scholar 

  • Walton, D., McDermid, J., Teasell, R., Nielson, W., Reese, H., & Levesque, L. (2011). Pressure pain threshold testing demonstrates predictive ability in people with acute whiplash. Journal of Orthopaedic & Sports Physical Therapy, 41(9), 658–665.

    Google Scholar 

  • Walton, D., Pretty, J., MacDermid, J., & Teasell, R. (2009). Risk factors for persistent problems following whiplash injury: Results of a systematic review and meta-analysis. Journal of Orthopaedic & Sports Physical Therapy, 39(5), 334–350.

    Google Scholar 

  • Williamson, E., Williams, M., Gates, S., & Lamb, S. (2008). A systematic review of psychological factors and the development of late whiplash syndrome. Pain, 135, 20–30.

    PubMed  Google Scholar 

  • Wilson, J.-P., & Keane, T. (1997). Assessing psychological trauma and PTSD. New York: Guilford Press.

    Google Scholar 

  • Woodhouse, A., & Vasseljen, O. (2008). Altered motor control patterns in whiplash and chronic neck pain. BMC Musculoskeletal Disorders, 9, 90.

    PubMed Central  PubMed  Google Scholar 

  • Yoganandan, N., Pintar, F., & Cusick, J. (2002). Biomechanical analyses of whiplash injuries using an experimental model. Accident Analysis and Prevention, 34, 663–671.

    Google Scholar 

  • Zhu, G., Lipsky, R., & Xu, K. (2004). Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5′ nuclease assay. Psychopharmacology, 177, 178–184.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michele Sterling Ph.D, M.Phty, B.Phty, F.A.C.P .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Science+Business Media New York

About this chapter

Cite this chapter

Sterling, M. (2014). The Problem of Whiplash Injuries: Aetiology, Assessment and Treatment. In: Gatchel, R., Schultz, I. (eds) Handbook of Musculoskeletal Pain and Disability Disorders in the Workplace. Handbooks in Health, Work, and Disability. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0612-3_7

Download citation

Publish with us

Policies and ethics