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Prognostic Factors

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Abstract

Identification and stratification of patients based on risk factors that predict for recurrence and progression of penile cancer are critical for patient and provider understanding of the disease as well as identification of appropriate therapy. Prognostic factors have primarily been studied in two clinical scenarios in penile cancer: (1) the identification of the patient with invasive primary cancer at high risk for developing inguinal lymph node metastases and (2) among those with inguinal lymph node metastases, predicting cancer-specific survival. Nomograms to predict for nodal metastases will allow the provider to carefully select patients for intervention on the lymph nodes while avoiding the potential side effect that such intervention may generate. Furthermore, a clear understanding of the factors which predict for survival will allow for optimal selection of patients for clinical trials.

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Correspondence to Joel Slaton MD .

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Appendix I

Appendix I

Instructions for Physicians: Locate the tumor thickness on the tumor thickness axis. Draw a line straight upward to the Points axis to determine the number of points received for tumor thickness. Repeat this process for the remaining axes, each time drawing straight upward to the Points axis. Sum the points achieved for each predictor and locate the sum on the Total Points axis. Draw a line straight down to find the 5-year cancer-specific survival of the patient.

Instructions to Patient: “Mr. X, if we had 100 men exactly like you, we would expect the predicted percentage from the nomogram to be free of disease-specific death in 5 years, assuming no one died of another cause.”

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Slaton, J. (2014). Prognostic Factors. In: Culkin, D. (eds) Management of Penile Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0461-7_5

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  • DOI: https://doi.org/10.1007/978-1-4939-0461-7_5

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