Abstract
HIV prevalence has been on the rise in many countries from which refugees emigrate and presents therapeutic challenges upon arrival to the United States. The HIV entry ban that previously prevented immigration of HIV-infected individuals into the United States has now been lifted. Refugees may acquire several risk factors prior to displacement and during migration. In addition, they may not have access to HIV treatment and prevention packages in conflict-ridden regions of the world. Therefore, refugee providers will need to be familiar with fundamental HIV testing and treatment principles, including for HIV-2, particularly as they pertain to refugees that may have co-morbid mental illness and/or who may be of child-bearing age. In addition, providers should recognize the clinical manifestations to diagnose and treat prevalent sexually transmitted infections among refugees, such as syphilis, gonorrhea, chancroid, granuloma inguinale, and lymphogranuloma venereum. This section will review the existing epidemiologic data from the Centers for Disease Control (CDC) and centers that provide care for refugees. It will also highlight key screening, testing, and management considerations for different HIV subtypes and other major sexually transmitted infections that are high-yield for providing care to refugee populations in a primary care setting.
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References
Global Report: UNAIDS Report on the Global AIDS Epidemic 2012. UNAIDS, Geneva. 2012. http://www.unaids.org/en/media/unaids/contentassets/documents/epidemiology/2012/gr2012/20121120_UNAIDS_Global_Report_2012_en.pdf. Accessed 21 Apr 2013.
Spiegel PB, Bennedsen AR, Claass J, et al. Prevalence of HIV infection in conflict-affected and displaced people in seven sub-Saharan African countries: a systematic review. Lancet. 2007;369:2187–95.
Holmes W. HIV and human rights in refugee settings. Lancet. 2001;358(9276):144–6.
U.S. Department of Health and Human Services (DHHS), Centers for Disease Control and Prevention (CDC), and National Center for Emerging and Zoonotic Infectious Diseases (NCEZID). Screening for HIV infection during the domestic medical examination for newly arrived refugees. 2012. http://www.cdc.gov/immigrantrefugeehealth/guidelines/domestic/sexually-transmitted-diseases.html. Accessed 9 Jul 2013.
Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services (HHS). Medical examination of aliens—removal of human immunodeficiency virus (HIV) infection from definition of communicable disease of public health significance. Fed Regist. 2009;74(210):56547–62. http://www.gpo.gov/fdsys/pkg/FR-2009-11-02/pdf/E9-26337.pdf. Accessed 21 Apr 2013.
Inter-Agency, UNAIDS/IOM Statement on HIV/AIDS-Related Travel Restrictions. June 2004. http://www.unhcr.org/refworld/docid/468249392.html. Accessed 21 Apr 2013.
Taylor K, Howard S. An end to the era of the US HIV entry ban. Clin Infect Dis. 2011;53(5):v. doi:10.1093/cid/cir548.
Branson BM, Handsfield HH, Lampe MA, et al. Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR Recomm Rep. 2006;55(RR-14):1–17.
Centers for Disease Control and Prevention (CDC). False-positive oral fluid rapid HIV tests—New York City, 2005–2008. MMWR Morb Mortal Wkly Rep. 2008;57:660–5.
Jain S, Lowman ES, Kessler A, et al. Seroprevalence study using oral rapid HIV testing in a large urban emergency department. J Emerg Med. 2012;43(5):e269–75.
Beckwith CG, DeLong AK, Desjardins SF, et al. HIV infection in refugees: a case-control analysis of refugees in Rhode Island. Int J Infect Dis. 2009;13(2):186–92.
Centers for Disease Control and Prevention (CDC). Human immunodeficiency virus type 2. HIV/AIDS fact sheets. Atlanta, GA: Centers for Disease Control and Prevention; 2007.
Popper SJ, Sarr AD, Travers KU, et al. Lower human immunodeficiency virus (HIV) type 2 viral load reflects the difference in pathogenicity of HIV-1 and HIV-2. J Infect Dis. 1999;180(4):1116–21.
Thompson MA, Aberg JA, Hoy JF, et al. Antiretroviral treatment of adult HIV infection: 2012 recommendations of the International Antiviral Society-USA panel. JAMA. 2012;308(4): 387–402.
Makadzange AT, Ndhlovu CE, Takarinda K, et al. Early versus delayed initiation of antiretroviral therapy for concurrent HIV infection and cryptococcal meningitis in sub-Saharan Africa. Clin Infect Dis. 2010;50(11):1532–8.
Campbell-Yesufu OT, Gandhi RT. Update on human immunodeficiency virus (HIV)-2 infection. Clin Infect Dis. 2011;52(6):780–7.
Moreno A, Labelle C, Samet JH. Recurrence of post-traumatic stress disorder symptoms after initiation of antiretrovirals including efavirenz: a report of two cases. HIV Med. 2003;4:302–4.
Aberg JA, Kaplan JE, Libman H, HIV Medicine Association of the Infectious Diseases Society of America, et al. Primary care guidelines for the management of persons infected with human immunodeficiency virus: 2009 update by the HIV medicine Association of the Infectious Diseases Society of America. Clin Infect Dis. 2009;49(5):651–81.
Stauffer WM, Painter J, Mamo B, et al. Sexually transmitted infections in newly arrived refugees: is routine screening for Neisseria gonorrhoeae and Chlamydia trachomatis infection indicated? Am J Trop Med Hyg. 2012;86(2):292–5.
Centers for Disease Control and Prevention (CDC). Health of resettled Iraqi refugees—San Diego County, California, October 2007–September 2009. MMWR Morb Mortal Wkly Rep. 2010;59(49):1614–8.
Hook EW. Endemic treponematoses. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. 6th ed. Philadelphia, PA: Elsevier; 2005. p. 2785–8.
Ballard RC, Koornhof HJ, Chen CY, et al. The influence of concomitant HIV infection on the serological diagnosis of primary syphilis in southern Africa. S Afr Med J. 2007;97(11 Pt 3): 1151–4.
Rompalo AM, Joesoef MR, O’Donnell JA, Syphilis and HIV Study Group, et al. Clinical manifestations of early syphilis by HIV status and gender: results of the syphilis and HIV study. Sex Transm Dis. 2001;28(3):158–65.
Rolfs RT, Joesoef MR, Hendershot EF, et al. A randomized trial of enhanced therapy for early syphilis in patients with and without human immunodeficiency virus infection. The Syphilis and HIV Study Group. N Engl J Med. 1997;337:307–14.
Knaute DF, Graf N, Lautenschlager S, et al. Serological response to treatment of syphilis according to disease stage and HIV status. Clin Infect Dis. 2012;55(12):1615–22.
Zetola NM, Engelman J, Jensen TP, et al. Syphilis in the United States: an update for clinicians with an emphasis on HIV coinfection. Mayo Clin Proc. 2007;82(9):1091–102.
Workowski KA, Berman S, Centers for Disease Control and Prevention (CDC). Sexually transmitted diseases treatment guidelines, 2010. MMWR Recomm Rep. 2010;59(RR-12):1–110.
Fleming DT, Wasserheit JN. From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection. Sex Transm Infect. 1999;75:3–17.
Centers for Disease Control and Prevention (CDC). Update to CDC’s Sexually transmitted diseases guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections. MMWR Morb Mortal Wkly Rep. 2012;61(31):590–4.
Del Rio C, Hall G, Homes K, et al. Update to CDC’s sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections. MMWR Morb Mortal Wkly Rep. 2012;61:590–4.
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Jain, S., Adelson-Mitty, J. (2014). HIV and Other Sexually Transmitted Infections: Testing and Treatment Considerations for Refugees. In: Annamalai, A. (eds) Refugee Health Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0271-2_9
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