Abstract
Although peritoneal dialysis is a form of portable and wearable dialysis, it requires patients to use fresh dialysate and either perform a number of manual daytime exchanges or use a cycler machine. As such the search has been to develop internal implantable, or external wearable or portable, devices that do not rely on a supply of fresh dialysate, so allowing patients to perform the activities of daily living without restriction, and similarly to be able to drink and eat freely without restriction.
Although the concept of wearable and portable dialysis devices dates back to the pioneering days of the start of dialysis as a long-term treatment for patients with advanced chronic kidney disease, it is only recently with developments in nanotechnology-manufacturing processes, coupled with microcircuit designs and the resurgent interest in sorbent technology that has allowed animal trials and now the first human trials of these devices to take place.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Lande AJ, Roberts M, Pecker EA (1977) In search of a 24 hours per day artificial kidney. J Dialysis. 1:805–23.
Jacobsen SC, Stephen RL, Bulloch EC, Luntz RD, Kolf WJ (1975) A wearable artificial kidney: functional description of hardware and clinical results. Proc Clin Dial Transplant Forum. 5:65–71.
Stephens RL, Jacobsen SC, Atkin-Thor E, Kolf WJ (1976) A portable wearable artificial kidney (WAK): initial evaluation. Proc Euro Dial Transplant Assoc. 12:511–18.
Kolff WJ, Jacobsen S, Stephen RL, Rose D (1976) Towards a wearable artificial kidney. Kidney Int. 7(suppl):S300–4.
Stephen RL, Kablitz C, Jacobsen S, Kolff WJ (1978) Combined technological clinical approach to wearable dialysis. Kidney Int suppl. 8:S125–32.
Blumenkrantz MJ, Gordon A, Roberts M, Lewin AJ, Pecker EA, Moran JK, Coburn JW, Maxwell MH (1979) Applications of the Redy sorbent system to hemodialysis and peritoneal dialysis. Artif Organs. 3(3):230–6.
Shaldon S, Beau MC, Deschodt G, Lysaght MJ, Ramperez P, Mion C (1980) Continuous ambulatory hemofiltration. Trans Am Soc Artif Intern Organs. 26:210–23.
Murisasco A, Baz M, Boobes Y, Bertocchio P, el Mehdi M, Durand C, Reynier JP, Ragon A (1986) A continuous hemofiltration system, using sorbents for hemofiltrate regeneration. Clin Nephrol. 26(Suppl. 1):S53–7.
Murisasco A, Reynier JP, Ragon A, Boobes Y, Baz M, Durand C, Bertocchio P, Agenet C, el Mehdi M (1986) Continuous arterio-venous hemofiltration in a wearable device to treat end-stage renal disease. Trans Am Soc Artif Intern Organs. 32:567–71.
Takahashi S (2012) Future home hemodialysis—advantages of the NxStage system one. Contrib Nephrol. 177:117–26.
Ronco C, Fecondini L (2007) The Vicenza wearable artificial kidney for peritoneal dialysis (ViWAK PD). Blood Purif. 25:383–8.
Roberts M, Ash SR, Lee DB (1999) Innovative peritoneal dialysis: flow-thru and dialysate regeneration. ASAIO J. 45(5):372–8.
Lee DBN, Roberts M (2008) A peritoneal based automated wearable artificial kidney. Clin Exper Nephrol. 12:171–80.
Maroni BJ, Steinman TI, Mitch WE (1985) A method for estimating nitrogen intake of patients with chronic renal failure. Kidney Int. 27:58–65.
Roberts M, Lee DBN (2006) Wearable artificial kidneys. A peritoneal dialysis approach. Dial Transplant. 36:780–2.
Wester M, Simonis F, Gerritsen KG, Boer WH, Wodzig WK, Kooman JP, Joles JA (2013) A regenerable potassium and phosphate sorbent system to enhance dialysis efficacy and device portability: an in vitro study. Nephrol Dial Transplant. 28(9):2364–71.
Gura V, Davenport A, Beizai M, Ezon C, Ronco C (2009) Beta 2-microglobulin and phosphate clearances using a wearable artificial kidney: a pilot study. Am J Kidney Dis. 54:104–11.
Davenport A, Gura V, Ronco C, Beizai M, Ezon C, Rambod E (2007) A wearable hemodialysis device for patients with end-stage renal failure: a pilot study. Lancet. 370:2005–10.
Gura V, Macy AS, Beizai M, Ezon C, Golper TA (2009) Technical breakthroughs in the wearable artificial kidney (WAK). Clin J Am Soc Nephrol. 4(9):1441–8.
Ash SR (2008) The Allient dialysis system. Semin Dial. 17:164–6.
Melvin ME, Fissell WH, Roy S, Brown DL (2010) Silicon induces minimal thrombo-inflammatory response during 28-Day intravascular implant testing. ASAIO J. 56:344–8.
Hofmann CL, Fissell WH (2010) Middle-molecule clearance at 20 and 35 ml/kg/h in continuous veno-venous haemodiafiltration. Blood Purif. 29:259–63.
Fissell WH, Dubnisheva A, Eldridge AN, Fleischman AJ, Zydney AL, Roy S (2009) High-performance silicon nanopore hemofiltration membranes. J Memb Sci. 326:58–63.
Holland NB, Qiu Y, Ruegsegger M, Marchant RE (1998) Biomimetic engineering of non-adhesive glycocalyx-like surfaces using oligosaccharide surfactant polymers. Nature. 392:799–801.
Fissell WH, Kimball J, MacKay SM, Funke A, Humes HD (2001) The role of a bioengineered artificial kidney in renal failure. Annals New York Acad Sci. 944:284–95.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Davenport, A. (2016). Wearable Dialysis Devices. In: Magee, C., Tucker, J., Singh, A. (eds) Core Concepts in Dialysis and Continuous Therapies. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7657-4_14
Download citation
DOI: https://doi.org/10.1007/978-1-4899-7657-4_14
Published:
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-7655-0
Online ISBN: 978-1-4899-7657-4
eBook Packages: MedicineMedicine (R0)