Abstract
Obstructive sleep apnea (OSA) is a common breathing disorder during sleep, characterized by recurrent upper airway obstruction resulting in physiologic perturbations and frequent nocturnal arousals. Nocturnal noninvasive ventilatory (nNIV) techniques utilizing positive airway pressure (PAP) devices delivered through a comfortable mask interface have provided effective and acceptable treatment for this disorder. Despite excellent clinical outcomes with PAP, lack of adherence remains a major issue in clinical sleep medicine. Innovations in the delivery of PAP have attempted to address a major cause of noncompliance—patient discomfort with PAP. In the following review, new delivery modes of PAP in patients with OSA is presented along with relevant data regarding their efficacy in altering patient adherence patterns and clinical outcomes. The methods of PAP delivery to be discussed include continuous PAP (CPAP), bi-level PAP (BPAP), autotitrating PAP (APAP), pressure relief (PR), and auto-bi-level PAP (Auto-BPAP).
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Weingarten, J. (2015). Use of nNIV in Obstructive Sleep Apnea: Modes, Flexes, and More. In: Basner, R., Parthasarathy, S. (eds) Nocturnal Non-Invasive Ventilation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7624-6_9
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DOI: https://doi.org/10.1007/978-1-4899-7624-6_9
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