Abstract
Spine care providers often treat patients with spondylolisthesis, which is slippage of a vertebra. There are different types of spondylolisthesis. Patients can have pain arising from multiple different pain generators associated with the different types of spondylolisthesis. In this chapter, we review the pathophysiology that leads to pain in patients with spondylolisthesis. We first review the pain generators that are common to all patients with spinal pathology. In the second part of the chapter, we review the pain generators that are unique to each type of spondylolisthesis. After reading this chapter, the reader should gain a better understanding of the pain generators in patients with spondylolisthesis. A better appreciation for the different pain generators will allow for more effective operative and nonoperative treatment.
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References
Edgar M. The nerve supply of the lumbar intervertebral disc. J Bone Joint Surg Br. 2007;89:1135–9.
Fujimoto K, Miyagi M, Ishikawa T, et al. Sensory and autonomic innervation of the cervical intervertebral disc in rats: the pathomechanics of chronic discogenic neck pain. Spine. 2012;37:1357–62.
van Kleef M, Vanelderen P, Cohen SP, Lataster A, Van Zundert J, Mekhail N. 12. Pain originating from the lumbar facet joints. Pain Pract. 2010;10:459–69.
Varlotta GP, Lefkowitz TR, Schweitzer M, et al. The lumbar facet joint: a review of current knowledge: Part II: diagnosis and management. Skeletal Radiol. 2011;40:149–57.
Smuck M, Crisostomo RA, Trivedi K, Agrawal D. Success of initial and repeated medial branch neurotomy for zygapophysial joint pain: a systematic review. PM R. 2012;4:686–92.
Jinkins JR, Rauch A. Magnetic resonance imaging of entrapment of lumbar nerve roots in spondylolytic spondylolisthesis. J Bone Joint Surg Am. 1994;76:1643–8.
Wiltse L, Guyer R, Spencer C, Glenn W, Porter I. Alar transverse process impingement of the L5 spinal nerve: the far-out syndrome. Spine. 1984;9:31–41.
Petron DJ, Prideaux CC, Likness L. Interventional spine procedures in athletes. Curr Sports Med Rep. 2012;11:335–40.
Wu SS, Lee CH, Cheng PQ. Operative repair of symptomatic spondylolysis following a positive response to diagnostic pars injection. J Spinal Disord. 1999;12:10–6.
Karatas AF, Dede O, Atanda AA, et al. Comparison of direct pars repair techniques of spondylolysis in pediatric and adolescent patients: pars compression screw versus pedicle screw-rod-hook. J Spinal Disord Tech. 2012 October 16 [Epub ahead of print].
Glassman SD, Berven S, Bridwell KH, Horton W, Dimar JR. Correlation of radiographic parameters and clinical symptoms in adult scoliosis. Spine. 2005;30:682–8.
Glassman SD, Bridwell KH, Dimar JR, Horton W, Berven S, Schwab F. The impact of positive sagittal balance in adult spinal deformity. Spine. 2005;30:2024–9.
Mac-Thiong JM, Transfeldt EE, Mehbod AA, et al. Can C7 plumbline and gravity line predict health related quality of life in adult scoliosis? Spine. 2009;34:E519–27.
Hanson DS, Bridwell KH, Rhee JM, Lenke LG. Correlation of pelvic incidence with low and high grade isthmic spondylolisthesis. Spine. 2002;27:2026–9.
Harroud A, Labelle H, Joncas J, Mac-Thiong JM. Global sagittal alignment and health-related quality of life in lumbosacral spondylolisthesis. Eur Spine J. 2013;22:849–56.
Hresko MT, Labelle H, Roussouly P, Berthonnaud E. Classification of high-grade spondylolisthesis based on pelvic version and spine balance – possible rationale for reduction. Spine. 2007;32:2208–13.
Labelle H, Roussouly P, Chopin D, Berthonnaud E, Hresko T, O’Brien M. Spino-pelvic alignment after surgical correction for developmental spondylolisthesis. Eur Spine J. 2008;17:1170–6.
Labelle H, Mac-Thiong JM, Roussouly P. Spino-pelvic sagittal balance of spondylolisthesis: a review and classification. Eur Spine J. 2011;20 Suppl 5:641–6.
Mehta VA, Amin A, Omeis I, Gokaslan ZL, Gottfried ON. Implications of spinopelvic alignment for the spine surgeon. Neurosurgery. 2012;70:707–21.
Aono K, Kobayashi T, Jimbo S, Atsuta Y, Matsuno T. Radiographic analysis of newly developed degenerative spondylolisthesis in a mean twelve-year prospective study. Spine. 2010;35:887–91.
Barrey C, Jund J, Perrin G, Roussouly P. Spinopelvic alignment of patients with degenerative spondylolisthesis. Neurosurgery. 2007;61:981–6.
Lim JK, Kim SM. Difference of sagittal spinopelvic alignments between degenerative spondylolisthesis and isthmic spondylolisthesis. J Korean Neurosurg Soc. 2013;53:96–101.
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Carragee, E.J., Stauff, M.P. (2015). Pain Generators in Spondylolisthesis. In: Wollowick, A., Sarwahi, V. (eds) Spondylolisthesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7575-1_3
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DOI: https://doi.org/10.1007/978-1-4899-7575-1_3
Publisher Name: Springer, Boston, MA
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