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Future Directions in Post-Traumatic Stress Disorder pp 133–153Cite as

Cutting Edge Research on Prevention of PTSD

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Abstract

Many studies have indicated that trauma exposure is highly prevalent with widespread negative consequences for both individuals and society as a whole. However, there are still no widely recommended treatment interventions that have demonstrated effectiveness at preventing the development of posttraumatic stress disorder (PTSD). Thus, although many individuals will experience natural recovery following exposure to a traumatic event, there are others who are at risk for chronic symptoms of traumatic stress, and there is a great need for effective interventions that are available in the immediate aftermath of a trauma that can assist these individuals and prevent PTSD. The following chapter provides an overview of predictors of PTSD development and reviews research on both psychological and pharmacological treatments that have been studied as potential early interventions for PTSD. In addition, the role of extinction and habituation in the development of PTSD is examined, along with cutting-edge translational research on an early exposure-based intervention for PTSD delivered to emergency room patients. Conclusions and suggestions for future research are discussed.

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References

  • Adler, A. B., Bliese, P. D., McGurk, D., Hoge, C. W., & Castro, C. A. (2009). Battlemind debriefing and Battlemind training as early interventions with soldiers returning from Iraq: Randomization by platoon. Journal of Consulting and Clinical Psychology, 77, 928–940.

    Article  PubMed  Google Scholar 

  • Adler, A. B., Castro, C. A., & McGurk, D. (2009). Time-driven Battlemind Psychological Debriefing: A group-level early intervention in combat. Military Medicine, 174, 21–28.

    Article  PubMed  Google Scholar 

  • Binder, E., Bradley, R., Liu, W., Epstein, M., Deveau, T., Binder, E., et al. (2008). FKBP5 polymorphisms moderate effects of child abuse on risk for PTSD in adults. Journal of the American Medical Association, 299(11), 1291–1305.

    Article  PubMed Central  PubMed  Google Scholar 

  • Bisson, J. I., Jenkins, P. L., Alexander, J., & Bannister, C. (1997). Randomised controlled trial of psychological debriefing for victims of acute burn trauma. British Journal of Psychiatry, 171, 78–81.

    Article  PubMed  Google Scholar 

  • Breslau, N., Kessler, R. C., Chilcoat, H. D., Schultz, L. R., Davis, G. C., & Andreski, P. (1998). Trauma and posttraumatic stress disorder in the community: the 1996 Detroit Area Survey of Trauma. Archives of General Psychiatry, 55, 626–632.

    Article  PubMed  Google Scholar 

  • Bryant, R. (2003). Early predictors of posttraumatic stress disorder. Society of Biological Psychiatry, 53, 789–795.

    Article  Google Scholar 

  • Bryant, R. A., Creamer, M., O’Donnell, M., Silove, D., & McFarlane, A. C. (2009). A study of protective function of acute morphine administration on subsequent posttraumatic stress disorder. Biological Psychiatry, 65, 438–440.

    Article  PubMed  Google Scholar 

  • Bryant, R. A., Harvey, A. G., Guthrie, R. M., & Moulds, M. L. (2000). A prospective study of psychophysiological arousal, acute stress disorder, and posttraumatic stress disorder. Journal of Abnormal Psychology, 109(2), 341–344.

    Article  PubMed  Google Scholar 

  • Bryant, R. A., Mastrodomenico, J., Felmingham, K. L., Hopwood, S., Kenny, L., Kandris, E., et al. (2008). Treatment of acute stress disorder: A randomized controlled trial. Archives of General Psychiatry, 65(6), 659–667. doi:10.1001/archpsyc.65.6.659.

    Article  PubMed  Google Scholar 

  • Bryant, R. A., Moulds, M. L., Guthrie, R. M., Dang, S. T., & Nixon, R. D. V. (2003). Imaginal exposure alone and imaginal exposure with cognitive restructuring in treatment of posttraumatic stress disorder. Journal of Consulting and Clinical Psychology, 71, 706–712.

    Article  PubMed  Google Scholar 

  • Bryant, R. A., Sackville, T., Dang, S., Moulds, M., & Guthrie, R. (1999). Treating acute stress disorder: An evaluation of cognitive behavior therapy and supportive counseling techniques. American Journal of Psychiatry, 156(11), 1780–1786.

    PubMed  Google Scholar 

  • Cougle, J. R., Keough, M. E., Riccardi, C. J., & Sachs-Ericsson, N. (2009). Anxiety disorders and suicidality in the National Comorbidity Survey-Replication. Journal of Psychiatric Research, 43(9), 825–829.

    Article  PubMed  Google Scholar 

  • Dalton, R., Scheeringa, M. S., & Zeanah, C. H. (2008). Did the prevalence of PTSD following Hurricane Katrina match a rapid needs assessment prediction? A template for future public planning after large-scale disasters. Psychiatric Annals, 38(2), 134–141.

    Article  Google Scholar 

  • Delahanty, D. L., Raimonde, A., & Spoonster, E. (2000). Initial posttraumatic urinary cortisol levels predict subsequent PTSD symptoms in motor vehicle accident victims. Biological Psychiatry, 48(9), 940–947.

    Article  PubMed  Google Scholar 

  • Devilly, G. J., Gist, R., & Cotton, P. (2006). Ready! Fire! Aim! The status of psychological debriefing and therapeutic interventions: In the work place and after disasters. Review of General Psychology, 10(4), 318–345.

    Article  Google Scholar 

  • Ehler, A., & Clark, D. (2003). Early psychological interventions for adult survivors of trauma: A review. Biological Psychiatry, 53, 817–826.

    Google Scholar 

  • Everly, G. R., Flannery, R. R., & Mitchell, J. T. (2000). Critical incident stress management (CISM): A review of the literature. Aggression and Violent Behavior, 5(1), 23–40.

    Article  Google Scholar 

  • Fletcher, S., Creamer, M., & Forbes, D. (2010). Preventing posttraumatic stress disorder: Are drugs the answer? Australian and New Zealand Journal of Psychiatry, 44, 1064–1071.

    Article  PubMed  Google Scholar 

  • Foa, E. B., Hembree, E. A., Cahill, S. P., Rauch, S. A. M., Riggs, D. S., Feeny, N. C., et al. (2005). Randomized trial of prolonged exposure for posttraumatic stress disorder with and without cognitive restructuring: Outcome at academic and community clinics. Journal of Consulting and Clinical Psychology, 73(5), 953–964. doi:10.1037/0022-006x.73.5.953.

    Article  PubMed  Google Scholar 

  • Foa, E. B., Hembree, E. A., & Rothbaum, B. (2007). Prolonged exposure therapy for PTSD: Emotional processing of traumatic experiences: Therapist guide. New York, NY: Oxford University Press.

    Google Scholar 

  • Foa, E. B., & Rothbaum, B. O. (1998). Treating the trauma of rape: Cognitive-behavioral therapy for PTSD. New York, NY: The Guilford Press.

    Google Scholar 

  • Foa, E. B., Rothbaum, R. O., Riggs, D. S., & Murdock, T. B. (1991). Treatment of posttraumatic stress disorder in rape victims: A comparison between cognitive-behavioral procedures and counseling. Journal of Consulting and Clinical Psychology, 59, 715–723.

    Article  PubMed  Google Scholar 

  • Foa, E. B., Zoellner, L. A., & Feeny, N. C. (2006). An evaluation of three brief programs for facilitating recovery after assault. Journal of Traumatic Stress, 19, 29–43.

    Article  PubMed  Google Scholar 

  • Galea, S., Ahern, J., Resnick, H., Kilpatrick, D., Bucuvalas, M., Gold, J., et al. (2002). Psychological sequelae of the September 11 terrorist attacks in New York city. New England Journal of Medicine, 346(13), 982–987.

    Article  PubMed  Google Scholar 

  • Gelpin, E., Bonne, O., Peri, T., & Brandes, D. (1996). Treatment of recent trama survivors with benzodiazepines: A prospective study. Journal of Clinical Psychiatry, 57, 390–394.

    PubMed  Google Scholar 

  • Gidron, Y., Gal, R., Freedman, S., Twiser, I., Lauden, A., Snir, Y., et al. (2001). Translating research findings to PTSD prevention: Results of a randomized-controlled pilot study. Journal of Traumatic Stress, 14(4), 773–780.

    Article  PubMed  Google Scholar 

  • Gidron, Y., Gal, R., Givati, G., Lauden, A., Snir, Y., & Benjamin, J. (2007). Interactive effects of memory structuring and gender in preventing posttraumatic stress symptoms. Journal of Nervous and Mental Disease, 195, 179–182.

    Article  PubMed  Google Scholar 

  • Greenberg, P. E., Sistsky, T., Kessler, R. C., Finkelstein, S. N., Berndt, E. R., Davidson, J. R., et al. (1999). The economic burden of anxiety disorder in the 1990’s. Journal of Clinical Psychiatry, 60, 427–435.

    Article  PubMed  Google Scholar 

  • Hembree, E. A., Rauch, S. A. M., & Foa, E. B. (2003). Beyond the manual: The insider’s guide to prolonged exposure therapy for PTSD. Cognitive and Behavioral Practice, 10(1), 22–30. doi:10.1016/s1077-7229(03)80005-6.

    Article  Google Scholar 

  • Hoge, E. A., Worthington, J. J., Nagurney, J. T., Chang, Y., Kay, E. B., Feterowski, C. M., et al. (2012). Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery. CNS Neuroscience and Therapeutics, 18, 21–27. doi:10.1111/j.1755-5949.2010.00227.x.

    Article  PubMed  Google Scholar 

  • Holbrook, T. L., Galarneau, M. R., Dye, J. L., Quinn, K., & Dougherty, A. L. (2010). Morphine use after combat injury in Iraq and posttraumatic stress disorder. New England Journal of Medicine, 362, 110–117.

    Article  PubMed  Google Scholar 

  • Hurlemann, R., Walter, H., Rehme, A. K., Kukolja, J., Santoro, S. C., Schmidt, C., et al. (2010). Human amygdale reactivity is diminished by the β-noradrenergic antagonist propranolol. Psychological Medicine, 40, 1839–1848.

    Article  PubMed  Google Scholar 

  • Jovanovic, T., Norrholm, S. D., Blanding, N. Q., Davis, M., Duncan, E., Bradley, B., et al. (2010). Impaired fear inhibition is a biomarker of PTSD but not depression. Depression and Anxiety, 27, 244–251.

    Article  PubMed Central  PubMed  Google Scholar 

  • Jovanovic, T., Norrholm, S. D., Fennell, J. E., Keyes, M., Fiallos, A., Meyers, K. M., et al. (2009). Posttraumatic stress disorder may be associated with impaired fear inhibition: Relation to symptom severity. Psychiatry Review, 167, 151–160.

    Google Scholar 

  • Kessler, R. C., Berglund, P., Delmer, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62(6), 593–602.

    Article  PubMed  Google Scholar 

  • Kessler, R. C., Sonnega, A., Bromet, E., Hughes, M., & Nelson, C. B. (1995). Posttraumatic stress disorder in the National Comorbidity Survey. Archives of General Psychiatry, 52(12), 1048–1060.

    Article  PubMed  Google Scholar 

  • Koenen, K. C., Saxe, G. G., Purcell, S. S., Smoller, J. W., Bartholomew, D. D., Miller, A. A., et al. (2005). Polymorphisms in FKBP5 are associated with peritraumatic dissociation in medically injured children. Molecular Psychiatry, 10(12), 1058–1059.

    Article  PubMed  Google Scholar 

  • Leserman, J., Drossman, D. A., Zhiming, L., Toomey, T. C., Nacman, G., & Glogau, L. (1996). Sexual and physical abuse history in gastroenterology practice: How types of abuse impact health status. Psychosomatic Medicine, 58, 4–15.

    Article  PubMed  Google Scholar 

  • Litz, B., Gray, M., Bryant, R., & Adler, A. (2002). Early intervention for trauma: Current status and future directions. Clinical Psychology: Science and Practice, 9(2), 112–134.

    Google Scholar 

  • Marciniak, M. D., Lage, M. J., Dunayevich, E., Russell, J. M., Bowman, L., Landbloom, R. P., et al. (2005). The cost of treating anxiety: The medical and demographic correlates that impact total medical costs. Depression and Anxiety, 21, 178–184.

    Article  PubMed  Google Scholar 

  • Mayou, R. A., Ehlers, A. A., & Hobbs, M. M. (2000). Psychological debriefing for road traffic accident victims: Three-year follow-up of a randomised controlled trial. British Journal of Psychiatry, 176, 589–593.

    Article  PubMed  Google Scholar 

  • McGhee, L. L., Maani, C. V., Garza, T. H., Gaylord, K. M., & Black, I. H. (2008). The correlation between ketamine and posttraumatic stress disorder in burned service members. Journal of Trauma-Injury Infection and Critical Care, 64(2 Suppl), S195–S199.

    Article  Google Scholar 

  • McSweeney, F. K., & Swindell, S. (2002). Common processes may contribute to extinction and habituation. The Journal of General Psychology, 129(4), 364–400.

    Article  PubMed  Google Scholar 

  • Mellman, T. A., Bustamante, V., David, D., & Fins, A. I. (2002). Hypnotic medication in the aftermath of trauma. Journal of Clinical Psychiatry, 63, 1183–1184.

    Article  PubMed  Google Scholar 

  • Miller, S. M., Brody, D. S., & Summerton, J. (1988). Styles of coping with threat: Implications for health. Journal of Personality and Social Psychology, 54, 142–148.

    Article  PubMed  Google Scholar 

  • Mitchell, J. T. (1983). When disaster strikes. The critical incident stress debriefing process. Journal of Emergency Medical Service, 8, 36–39.

    Google Scholar 

  • Mitchell, J. T., & Everly, G. S., Jr. (1996). Critical incident stress debriefing: An operations manual for the prevention of traumatic stress among emergency services and disaster workers (2nd ed.). Ellicott City, MD: Chevron Publishing Corporation.

    Google Scholar 

  • Myers, K. M., & Davis, M. (2002). Behavioral and neural analysis of extinction. Neuron, 36, 567–584.

    Article  PubMed  Google Scholar 

  • Myers, K. M., Ressler, K. J., & Davis, M. (2006). Different mechanisms of fear extinction dependent on length of time since fear acquisition. Learning and Memory, 13, 216–223.

    Article  PubMed Central  PubMed  Google Scholar 

  • Nixon, R. D. V., Nehmy, T. J., Ellis, A. A., Ball, S. A., Menne, A., & McKinnon, A. C. (2010). Predictors of posttraumatic stress in children following injury: The influence of appraisals, heart rate, and morphine use. Behaviour Research and Therapy, 48(8), 810–815.

    Article  PubMed  Google Scholar 

  • Norrholm, S. D., Jovanovic, T., Olin, I. W., Sands, L. A., Karapanou, I., Bradley, B., et al. (2011). Fear extinction in traumatized civilians with posttraumatic stress disorder: Relation to symptom severity. Biological Psychiatry, 69, 556–563.

    Article  PubMed Central  PubMed  Google Scholar 

  • Norrholm, S. D., Jovanovic, T., Vervliet, B., Boshoven, W., Myers, K. M., Davis, M., et al. (2008). Timing of extinction relative to acquisition: A parametric analysis of fear extinction in humans. Behavioral Neuroscience, 122, 1016–1030.

    Article  PubMed Central  PubMed  Google Scholar 

  • Norris, F. H. (1992). Epidemiology of trauma: Frequency and impact of different potentially traumatic events on different demographic groups. Journal of Consulting and Clinical Psychology, 60(3), 409–418.

    Article  PubMed  Google Scholar 

  • Ozer, E. J., Best, S. R., Lipsey, T. L., & Weiss, D. S. (2008). Predictors of posttraumatic stress disorder and symptoms in adults: A meta-analysis. Psychological Trauma: Theory, Research, Practice, and Policy, S(1), 3–36.

    Article  Google Scholar 

  • Pitman, R. K., & Delahanty, D. L. (2005). Conceptually driven pharmacologic approaches to acute trauma. CNS Spectrums, 10, 99–106.

    PubMed  Google Scholar 

  • Pitman, R., Sanders, K., Zusman, R., Healy, A., Cheema, F., & Lasko, N. (2002). Pilot study of secondary prevention of posttraumatic stress disorder with propranolol. Biological Psychiatry, 51(2), 189–192.

    Article  PubMed  Google Scholar 

  • Pole, N., Neylan, T. C., Otte, C., Henn-Hasse, C., Metzler, T. J., & Marmar, C. R. (2009). Prospective prediction of posttraumatic stress disorder symptoms using fear potentiated auditory startle responses. Biological Psychiatry, 65(3), 235–240.

    Article  PubMed Central  PubMed  Google Scholar 

  • Powers, M. B., Halpern, J. M., Ferenschak, M. P., Gillihan, S. J., & Foa, E. B. (2010). A meta- analytic review of prolonged exposure for posttraumatic stress disorder. Clinical Psychology Review, 30, 635–641. doi:10.1016/j.cpr.2010.04.007.

    Article  PubMed  Google Scholar 

  • Resnick, H., Acierno, R., Holmes, M., Kilpatrick, D. G., & Jager, N. (1999). Prevention of post- rape psychopathology: Preliminary findings of controlled acute rape treatment study. Journal of Anxiety Disorders, 13, 359–370.

    Article  PubMed  Google Scholar 

  • Resnick, H., Acierno, R., Kilpatrick, D. G., & Holmes, M. (2005). Description of an early intervention to prevent substance abuse and psychopathology in recent rape victims. Behavior Modification, 29, 156–188.

    Article  PubMed  Google Scholar 

  • Resnick, H., Acierno, R., Waldrop, A. E., King, L., King, D., Danielson, C., et al. (2007). Randomized controlled evaluation of an early intervention to prevent post-rape psychopathology. Behaviour Research and Therapy, 45, 2432–2447.

    Article  PubMed Central  PubMed  Google Scholar 

  • Resnick, H. S., Kilpatrick, D. G., Best, C. L., & Kramer, T. L. (1992). Vulnerability-stress factors in development of posttraumatic stress disorder. Journal of Nervous and Mental Disease, 180(7), 424–430.

    Article  PubMed  Google Scholar 

  • Resnick, H. S., Yehuda, R., Pitman, R. K., & Foy, D. W. (1995). Effect of previous trauma on acute plasma cortisol level following rape. The American Journal of Psychiatry, 152(11), 1675–1677.

    Article  PubMed  Google Scholar 

  • Ressler, K. J., Mercer, K. B., Bradley, B., Jovanovic, T., Mahan, A., Kerley, K., et al. (2011). Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature, 470, 492–497.

    Article  PubMed Central  PubMed  Google Scholar 

  • Roberts, N. P., Kitchiner, N. J., Kenardy, J., & Bisson, J. I. (2009). Systematic review and meta-analysis of multiple-session early interventions following traumatic events. American Journal of Psychiatry, 166, 293–301.

    Google Scholar 

  • Rose, S., Bisson, J., Churchill, R., Wessely, S. (2002). Psychological debriefing for preventing post traumatic stress disorder (PTSD). The Cochrane Database of Systematic Review, (2), CD000560.

    Google Scholar 

  • Rothbaum, B. O., Astin, M. C., & Marsteller, F. (2005). Prolonged exposure vs. EMDR for PTSD rape victims. Journal of Traumatic Stress, 18, 607–616.

    Article  PubMed  Google Scholar 

  • Rothbaum, B. O., Foa, E. B., Riggs, D. S., Murdock, T., & Walsh, W. (1992). A prospective examination of posttraumatic stress disorder in rape victims. Journal of Traumatic Stress, 5, 455–475.

    Article  Google Scholar 

  • Rothbaum, B. O., Houry, D., Heekin, M., Leiner, A. S., Daugherty, J., Smith, L. S., et al. (2008). A pilot study of an exposure-based intervention in the ED designed to prevent posttraumatic stress disorder. American Journal of Emergency Medicine, 26, 326–330.

    Article  PubMed  Google Scholar 

  • Rothbaum, B. O., Kearns, M. C., Price, M., Malcoun, E., Davis, M., Ressler, K. J., et al. (2012). Early intervention may prevent the development of posttraumatic stress disorder: A randomized pilot civilian study with modified prolonged exposure. Biological Psychiatry, 72(11), 957–963.

    Article  PubMed Central  PubMed  Google Scholar 

  • Rothbaum, B.O., Kearns, M.C., Reiser, E., Davis, J.S., Kerley, K.A., Rothbaum, A.O., et al. (in press). Early intervention following trauma may mitigate genetic risk for PTSD in civilians: A pilot prospective emergency department study. Journal of Clinical Psychiatry , 75.

    Google Scholar 

  • Rothbaum, B. O., Kozak, M. J., Foa, E. B., & Whitaker, D. J. (2001). Posttraumatic stress disorder in rape victims: Autonomic habituation to auditory stimuli. Journal of Traumatic Stress, 14, 283–293.

    Article  PubMed  Google Scholar 

  • Saxe, G., Stoddard, F., Courtney, D., Cunningham, K., Chawla, N., Sheridan, R., et al. (2001). Relationship between acute morphine and the course of PTSD in children with burns. Journal of American Academy of Child Adolescent Psychiatry, 40(8), 915–921.

    Article  Google Scholar 

  • Saxe, G. N., Stoddard, F., Hall, E., Chawla, N., Lopez, C., Sheridan, R., et al. (2005). Pathways to PTSD, Part I: Children with burns. The American Journal of Psychiatry, 162(7), 1299–1304.

    Article  PubMed  Google Scholar 

  • Scholes, C., Turpin, G., & Mason, S. (2007). A randomised controlled trial to assess the effectiveness of providing self-help information to people with symptoms of acute stress disorder following a traumatic injury. Behaviour Research and Therapy, 45, 2527–2536.

    Article  PubMed  Google Scholar 

  • Schonenberg, M., Reichwald, U., Domes, G., Badke, A., & Hautzinger, M. (2005). Effects of peritraumatic ketamine medication on early and sustained posttraumatic stress symptoms in moderately injured accident victims. Psychopharmacology, 182, 420–425.

    Article  PubMed  Google Scholar 

  • Segman, R. H., Shefi, N. N., Goltser-Dubner, T. T., Friedman, N. N., Kaminski, N. N., & Shalev, A. Y. (2005). Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors. Molecular Psychiatry, 10(5), 500–513.

    Article  PubMed  Google Scholar 

  • Shalev, A. Y., Sahar, T., Freedman, S., Peri, T., Glick, N., Brandes, D., et al. (1998). A prospective study of heart rate response following trauma and the subsequent development of posttraumatic stress disorder. Archives of General Psychiatry, 55, 553–559.

    Article  PubMed  Google Scholar 

  • Sijbrandij, M., Olff, M., Reitsma, J. B., Carlier, I. E., & Gersons, B. R. (2006). Emotional or educational debriefing after psychological trauma: Randomised controlled trial. British Journal of Psychiatry, 189(2), 150–155.

    Article  PubMed  Google Scholar 

  • Stein, M. B., Kerridge, C., Dimsdale, J. E., & Hoyt, D. B. (2007). Pharmacotherapy to prevent PTSD: Results from a randomized controlled proof-of-concept trial in physically injured patients. Journal of Traumatic Stress, 20, 923–932.

    Article  PubMed  Google Scholar 

  • Suveg, C. (2007). Implications of the debriefing debate for research and clinical practice. Clinical Psychology: Science and Practice, 14(2), 117–120.

    Google Scholar 

  • Tanielian, T., & Jaycox, L. H. (Eds.). (2008). Invisible wounds of war: Psychological and cognitive injuries, their consequences, and serves to assist recovery. Santa Monica, CA: RAND Corporation.

    Google Scholar 

  • Tuckey, M. R. (2007). Issues in the debriefing debate for the emergency services: Moving research outcomes forward. Clinical Psychology: Science and Practice, 14(2), 106–116.

    Google Scholar 

  • Turpin, G., Downs, M., & Mason, S. (2005). Effectiveness of providing self-help information following acute traumatic injury: Randomised controlled trial. British Journal of Psychiatry, 187, 76–82.

    Article  PubMed  Google Scholar 

  • Vaiva, G., Ducrocq, F., Jezequel, K., Averland, B., Lestavel, P., Brunet, A., et al. (2003). Immediate treatment with propranolol decreases posttraumatic stress disorder two months after trauma. Biological Psychiatry, 54, 947–949.

    Article  PubMed  Google Scholar 

  • Xie, P., Kranzler, H. R., Poling, J., Stein, M. B., Anton, R. F., Farrer, L. A., et al. (2010). Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Neuropsychopharmacology, 35(8), 1684–1692.

    PubMed Central  PubMed  Google Scholar 

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Authors and Affiliations

  1. Emory University School of Medicine, 1256 Briarcliff Road, Atlanta, GA, 30306, USA

    Megan C. Kearns Ph.D., Cole G. Youngner B.A., Mark S. Burton B.A., Alexander McCarthy & Barbara Olasov Rothbaum Ph.D., ABPP

  2. Virtually Better, Inc., 2440 Lawrenceville Hwy, Decatur, GA, 30033, USA

    Alex O. Rothbaum

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  1. Megan C. Kearns Ph.D.
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  2. Alex O. Rothbaum
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  3. Cole G. Youngner B.A.
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  4. Mark S. Burton B.A.
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  5. Alexander McCarthy
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  6. Barbara Olasov Rothbaum Ph.D., ABPP
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Correspondence to Barbara Olasov Rothbaum Ph.D., ABPP .

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Editors and Affiliations

  1. Department of Psychology, University of Haifa, Haifa, Israel

    Marilyn P. Safir

  2. Department of Psychology, University of Haifa, Haifa, Israel

    Helene S. Wallach

  3. Department of Psychiatry and School of Gerontology, University of Southern California Institute for Creative Technologies, Los Angeles, California, USA

    Albert "Skip" Rizzo

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Kearns, M.C., Rothbaum, A.O., Youngner, C.G., Burton, M.S., McCarthy, A., Rothbaum, B.O. (2015). Cutting Edge Research on Prevention of PTSD. In: Safir, M., Wallach, H., Rizzo, A. (eds) Future Directions in Post-Traumatic Stress Disorder. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7522-5_6

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