Abstract
Movement disorders are conditions in which there is either a paucity or excess of movements. Classification systems are based on clinical findings, anatomy, pathology, etiology, and genetics, none of which are perfect. Classification by genetic etiology is complicated by heterogeneity, in which many genes cause the same phenotype, as well as pleiotropy, in which mutations in a single gene can result in different phenotypes. Genetic counseling for movement disorders is also complicated by having both Mendelian and multifactorial causes of disease. This section reviews the different types of movement disorders and the issues for genetic counseling.
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Bower, M., Tuite, P. (2015). Overview of Movement Disorders. In: Goldman, J. (eds) Genetic Counseling for Adult Neurogenetic Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7482-2_1
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DOI: https://doi.org/10.1007/978-1-4899-7482-2_1
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