Drug-Induced or Spontaneous Psychopathological Changes and the Relationship to Quantitative Electroencephalography
In a longitudinal study of a group of therapy-resistant schizophrenic subjects, concurrent psychopathological and quantitative EEG measures were compared. Fifteen patients were observed for periods of from 10 to 24 months. In eight patients, periods of improved behavior were observed, while in seven no such improvent occurred. The changes were observed both during placebo and active drug therapy periods.