Abstract
The ultimate goal of Hodgkin’s disease (HD) therapy is no longer merely to achieve the cure of the patients, but to reach the Holy Grail of ‘uncomplicated cure.’ Actually, a cure associated with a low risk of benign complications might be acceptable in most cases.
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References
Tubiana M, Henry-Amar M, Carde P et al. Towards comprehensive management tailored to prognostic factors of patients with clinical stage I and II in Hodgkin’s disease. The EORTC lymphoma group controlled clinical trials 1964–1987. Blood 1989; 73: 47–56.
Hohl RJ, Schlilsky RL. Non malignant complications of therapy for Hodgkin’s disease. Hematology/Oncology Clinics of North America 1989; 3: 331–43.
Cosset JM, Henry-Amar M, Burgers JMV et al. Late radiation injuries of the gastro-intestinal tract in the H2 and H5 EORTC Hodgkin’s disease trials: Emphasis on the role of exploratory laparotomy and fractionation. Radiother Oncol 1988; 13: 618.
Gallez-Marchal D, Fayolle M, Henry-Amar M et al. Radiation injuries of the gastro-intestinal tract in Hodgkin’s disease: The role of exploratory laparotomy and fractionation. Radiother Oncol 1984; 2: 93–9.
Thames HD, Hendry JH. Fractionation in radiotherapy. London: Taylor and Francis, 1987.
Cosset JM, Henry-Amar M, Girinsky T et al. Late toxicity of radiotherapy in Hodgkin’s disease: The role of fraction size. Acta Oncologica 1988; 27: 113–29.
Host H, Vale JR. Lung function after mantle field irradiation in Hodgkin’s disease. Cancer 1973; 32: 328–32.
Evans RF, Sagerman RH, Ringrose TL et al. Pulmonary function following mantle field irradiation for Hodgkin’s disease. Radiology 1974; 111: 729–31.
Watchie J, Coleman CN, Raffin TA et al. Minimal long term cardiopulmonary dysfunction following treatment for Hodgkin’s disease. Int J Radiat Oncol Biol Phys 1989; 16: 79–84.
Smith LM, Mendenhall NP, Cicale MJ et al. Results of a prospective study evaluating the effects of mantle irradition on pulmonary function. Int J Radiat Oncol Biol Phys 1989; 16: 7984.
Cosset JM, Henry-Amar M, Thomas J et al. Increased pulmonary toxicity in the ABVD arm of the EORTC H6-U trial. Proc Am Soc Clin Oncol 1989; 8: 253.
Zucali R, Pagnoni AM, Zanini M et al. Radiobiological and spirometric evaluation of mediastinal and pulmonary late effects after radiotherapy and chemotherapy for Hodgkin’s disease. J Eur Radiother 1981; 2: 169–76.
Boivin JF, Hutchison GB. Coronary heart disease mortality after irradiation of Hodgkin’s disease. Cancer 1982; 49: 24705.
Pohjola-Sintonen S, Totterman KJ, Salmo M et al. Late cardiac effects of mediastinal radiotherapy in patients with Hodgkin’s disease. Cancer 1987; 60: 31–7.
Hancock SL, Hoppe RT, Horning SJ et al. Intercurrent death after Hodgkin’s disease therapy in radiotherapy and adjuvant MOPP trials. Ann Int Med 1988; 109: 183–9.
Rijswijk REN, Verbeek J, Haanen C et al. Major complications and causes of death in patients treated for Hodgkin’s disease. J Clin Oncol 1987; 5: 1624–33.
Cosset JM, Henry-Amar M, Pellae Cosset B et al. Pericarditis and myocardial infarctions after Hodgkin’s disease therapy at the Institut Gustave-Roussy. Int J Radiat Oncol Biol Phys 1990 (in press).
Corn BW, Trock BJ, Goodman RL. Irradiation-related ischaemic heart disease. J Clin Oncol 1990; 8: 741–50.
Henry-Amar M, Somers R. Long-term survival in early stages Hodgkin’s disease: The EORTC experience. In: Treatment Strategy in Hodgkin’s disease, Somers R, Henry-Amar M, Meerwaldt JH, Carde P (eds). Colloque INSERM no 196. London, Paris: INSERM/John Libbey Eurotext, 1990; 151–66.
Henry-Amar M. Risk of second cancer after therapy for early stage Hodgkin’s disease: The EORTC experience. Int J Radiat Oncol Biol Phys 1990 (in press).
Henry-Amar M, Pellae-Cosset B, Bayle-Weisgerber C et al. Risk of secondary acute leukemia and preleukemia after Hodgkin’s disease. The Institut Gustave-Roussy experience. In: New aspects in the diagnosis and treatment of Hodgkin’s disease. Diehl V, Pfreundschuh M, Diehl V, 1989; 117: 270–83.
Pedersen-Bjergaard J, Specht L, Larsen SO et al. Risk of therapy-related leukemia and preleukemia after Hodgkin’s disease. Relation to age, cumulative dose of alkylating agents, and time from chemotherapy. Lancet 1987; ii: 83–88.
Kaldor JM, Day NE, Clarke EA et al. Leukemia following Hodgkin’s disease. N Engl J Med 1990; 322: 7–13.
Van Leeuwen FE, Somers R, Hart AAM. Splenectomy in Hodgkin’s disease and second leukemia. Lancet 1987; 2: 2101.
Leeuwen FE, Somers R, Tall BG et al. Increased risk of lung cancer, non-Hodgkin’s lymphoma, and leukemia following Hodgkin’s disease. J Clin Oncol 1989; 7: 1046–58.
Velden JW, Putten WL, Gurnee VF et al. Subsequent development of acute non-lymphocytic leukemias in patients treated for Hodgkin’s disease. Int J Cancer 1988; 42: 252–5.
Henry-Amar M, Somers R. Survival outcome after Hodgkin disease. A report from the International Database on Hodgkin disease (IDHD) Seminars in Oncology 1990 (in press).
Somers R, Henry-Amar M, Meerwaldt JH, Carde P (eds). Treatment Strategy in Hodgkin’s disease. Statistical report, part X. Colloque INSERM no 196. London, Paris: INSERM/John Libbey Eurotext, 1990; 381–418.
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Cosset, J.M., Henry-Amar, M., Meerwaldt, J.H., EORTC Lymphoma Cooperative Group. (1991). Long-term toxicity of early stages of Hodgkin’s disease therapy: The EORTC experience. In: Ultmann, J.E., Samuels, B.L. (eds) Annals of Oncology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7305-4_13
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DOI: https://doi.org/10.1007/978-1-4899-7305-4_13
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