Abstract
We have already seen that degradative enzymes are widespread in cells, and that eukaryotic cells have a specialized degradative organelle, the lysosome. Now we consider how the activities of the various degradative routes are integrated, and how they work with the selectivity which is observed. And it should be admitted immediately that we here deal more with hypotheses than with established mechanism.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Bibliography
Dean, R. T., (1975), Biochem. Biophys. Res. Commun, 67, 604–609.
On selectivity in autophagy.
Goldstein, J. L. and Brown, M. S. (1977), The low density lipoprotein pathway and its relation to atherosclerosis, Ann. Rev. Biochem., 46, 897–930.
Excellent on LDL uptake.
Gregoriadis, G. (1975), The catabolism of glycoproteins, In Lysosomes in Biology and Pathology, Vol. 4, (Eds.) J. T. Dingle and R. T. Dean, pp. 265-294, North Holland, Amsterdam.
Covers the liver uptake system.
Michell, R. H. (1975), Inositol phospholipids and cell surface receptor function, Biochim. Biophys. Acta, 415, 81–147.
A stimulating review.
Mortimore, G. E. and Schworer, C. M., (1977), Nature (London), 270, 174–176.
Variation in rates of autophagy.
Hammarstrom, S. (1975), Prostaglandins, Ann. Rev. Biochem., 44, 669–695.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1978 R. T. Dean
About this chapter
Cite this chapter
Dean, R.T. (1978). Mechanisms and control of cellular degradation. In: Cellular Degradative Processes. Outline Studies in Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7230-9_6
Download citation
DOI: https://doi.org/10.1007/978-1-4899-7230-9_6
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-412-15190-3
Online ISBN: 978-1-4899-7230-9
eBook Packages: Springer Book Archive