Skip to main content

Linear IgA disease of childhood (chronic bullous disease of childhood)

  • Chapter
Management of Blistering Diseases

Abstract

Linear IgA disease of childhood (LADC) (synonyms juvenile dermatitis herpetiformis, juvenile pemphigoid, chronic bullous disease/ dermatosis of childhood) is an acquired blistering disorder of childhood characterized by the presence of a linear band of IgA at the dermo-epidermal junction.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Fox, T. (1873) in Skin Diseases, Renshaw, London, pp. 217–22.

    Google Scholar 

  2. Alexander, J.O.D. (1975) in Dermatitis Herpetiformis, W.B. Saunders Co., London, pp. 31–42.

    Google Scholar 

  3. Bowen, J.T. (1901) Five cases of bullous dermatitis (DH) in children following vaccination. Brit. J. Dermatol., 8, 392–4.

    Google Scholar 

  4. Bowen, J.T. (1905) Dermatitis herpetiformis in children. J. Cutan. Dis., 23, 79–85.

    Google Scholar 

  5. Kim, R. and Winkelmann, R.K. (1961) Dermatitis herpetiformis in children. Arch. Dermatol., 83, 895–902.

    Article  PubMed  CAS  Google Scholar 

  6. Jordan, R.E., Bean, S.F., Triftshauser, C.T. and Winkelmann, R.K. (1970) Childhood bullous dermatitis herpetiformis. Arch. Dermatol., 101, 629–34.

    Article  Google Scholar 

  7. Marsden, R.A., Skeete, M.V.H. and Black, M.M. (1979) The chronic acquired bullous diseases of childhood. Clin. Exp. Dermatol., 4, 227–40.

    Article  PubMed  CAS  Google Scholar 

  8. Bean, S.F., Jordan, R.E., Winkelmann, R.K. and Good, R.A. (1971) Chronic non-hereditary blistering diseases in children. Amer. J. Dis. Childh., 122, 137–41.

    Article  CAS  Google Scholar 

  9. Chorzelski, T.P. and Jablonska, S. (1979) Linear IgA dermatosis of childhood (chronic bullous diseases of childhood). Brit. J. Dermatol., 101, 535–42.

    Article  CAS  Google Scholar 

  10. Marsden, R.A., McKee, P.H., Bhogal, B., et al. (1980) A study of benign chronic bullous dermatosis of childhood and comparison with dermatitis herpetiformis and bullous pemphigoid occurring in childhood. Clin. Exp. Dermatol., 5, 159–72.

    Article  PubMed  CAS  Google Scholar 

  11. Marsden, R.A., Wojnarowska, F., McKee, P.H. and Black, M.M. (1988) Chronic bullous disease of Advances in Diagnosis and Treatment (eds R. Happle and E. Grosshans), Springer-Verlag, Berlin, pp. 75–81.

    Google Scholar 

  12. Wojnarowska, F., Marsden, R.A., Bhogal, B. and Black, M.M. (1989) Chronic bullous disease of childhood, childhood cicatricial pemphigoid and linear IgA disease of adults, a comparative study demonstrating clinical and immunological overlap. J. Amer. Dermatol., 9, 792–805.

    Google Scholar 

  13. Warner, J., Brooks, S.E.H., James, W.P.T. and Louisy, S. (1972) Juvenile dermatitis herpetiformis in Jamaica: Clinical and gastrointestinal features. Brit. J. Dermatol., 86, 226–37.

    Article  CAS  Google Scholar 

  14. Ratnam, K.V., Lee, C.T. and Tan, T. (1986) Chronic bullous dermatosis of childhood in Singapore. Int. J. Dermatol., 25, 34–7.

    Article  PubMed  CAS  Google Scholar 

  15. Actam, B.A. and Rajagopalan, K. (1979) Immunofluorescence in chronic bullous dermatosis of childhood. Austr. J. Dermatol., 20, 46–8.

    Article  Google Scholar 

  16. Horiguchi, Y., Toda, K.I., Okamoto, H. and Imamura, S. (1986) Immunoelectron-microscopic observations in a case of linear IgA bullous dermatosis of childhood. J. Amer. Acad. Dermatol., 14, 593–9.

    Article  CAS  Google Scholar 

  17. Piamphongsant, T., Sirimachan, S. and Himmunknan, P. (1986) Juvenile blistering diseases: the problems of diagnosis and treatment. Asian-Pacific J. Allergy Immunol., 4, 133–7.

    CAS  Google Scholar 

  18. Wright, S. and Nkrumah, F.K. (1984) Chronic bullous dermatosis of childhood. Cent. Afr. J. Med., 30, 165–9.

    PubMed  CAS  Google Scholar 

  19. Reid, C., Wojnarowska, F., Pothupitiya, G., et al. (1988) Chronic bullous disease of childhood around the world. Brit. J. Dermatol., 119, Suppl. 33, 41.

    Article  Google Scholar 

  20. Berlin, C. (1952) Dermatitis herpetiformis in children. Brit. J. Dermatol., 64, 281–90.

    Article  CAS  Google Scholar 

  21. Leigh, G., Marsden, R.A. and Wojnarowska, F. (1988) Linear IgA dermatosis with severe arthralgia. Brit. J. Dermatol., 119, 789–92.

    Article  CAS  Google Scholar 

  22. Marsden, R.A. and Greaves, M.W. (1982) Atypical bullous dermatosis of childhood with entropion. J. R. Soc. Med., 75, 39–41.

    PubMed  CAS  Google Scholar 

  23. Wojnarowska, F., Marsden, R.A., Bhogal, B. and Black, M.M. (1984) Childhood cicatricial pemphigoid with linear IgA deposits. Clin. Exp. Dermatol., 9, 407–15.

    Article  PubMed  CAS  Google Scholar 

  24. Ackerman, A.B. (1978) Bullous diseases of childhood. In Histologic Diagnosis of Inflammatory Skin Disease, Lea and Febiger, Philadelphia, pp. 628–9.

    Google Scholar 

  25. Kelly, S.E., Frith, P.A., Millard, P.R., et al. (1988) A clinicopathological study of mucosal involvement in linear IgA disease. Brit. J. Dermatol., 119, 161–70.

    Article  CAS  Google Scholar 

  26. Bhogal, B., Wojnarowska, F., Marsden, R.A., et al. (1987) Linear IgA bullous dermatosis of adults and children. An immunoelectronmicroscopic study. Brit. J. Dermatol., 117, 289–96.

    Article  CAS  Google Scholar 

  27. Aboobaker, J., Bhogal, B., Wojnarowska, F., et al. (1987) The localisation of circulating IgA antibodies in linear IgA disease, chronic bullous disease of childhood and childhood cicatricial pemphigoid using suction blisters as substrate. Brit. J. Dermatol., 116, 293–303.

    Article  CAS  Google Scholar 

  28. Wojnarowska, F., Pothupitiya, G.M., Bhogal, B., et al. (1987) in Immunodermatology (ed. R. Caputo), CIC Edizioni Internazionali, Rome, pp. 237–9.

    Google Scholar 

  29. Meenan, F.O.C. and Cahalane, S.F. (1969) Bullous pemphigoid of childhood and coeliac disease. Brit. J. Dermatol., 81, 777–9.

    Article  CAS  Google Scholar 

  30. Del Forno, C., Giannetti, A. and Orecchia, G. (1979) Chronic bullous dermatosis of childhood. Acta Dermatovenereol. (Stockholm), 59, 178–80.

    Google Scholar 

  31. Brandrup, F. and Schmidt, H. (1981) Benign chronic bullous dermatosis associated with coeliac disease. Clin. Exp. Dermatol., 6, 569–70.

    Article  PubMed  CAS  Google Scholar 

  32. Marsden, R.A. (1981) Benign chronic bullous dermatosis of childhood associated with coeliac disease — a reply. Clin. Exp. Dermatoi., 6, 570–1.

    Article  Google Scholar 

  33. Meurer, M., Kuhnle, U. and Bertele-Harms, R. (1984) Dermatosis herpetiformis Duhring with coeliac disease and growth retardation: Rapid and complete remission with gluten-free diet. Clinical Case Report, First Congress of the European Society for Pédiatric Dermatology, Munster, 4–7 October, 1984.

    Google Scholar 

  34. Meeuwisse, G.W. (1970) Diagnostic criteria in coeliac disease. Acta Paediatr. Scand., 59, 461–3.

    Article  Google Scholar 

  35. Pothupitiya, G.M., Wojnarowska, F., Bhogal, B.S. and Black, M.M. (1988) Distribution of the antigen in adult linear IgA disease and chronic bullous dermatosis of childhood suggests that it is a single and unique antigen. Brit. J. Dermatol., 118, 175–82.

    Article  CAS  Google Scholar 

  36. Wojnarowska, F., Whitehead, P., Bhogal, B., et al. (1988) Characterisation of the antigen in chronic bullous dermatosis of childhood and adult linear IgA disease. Brit. J. Dermatol., 118, 268.

    Google Scholar 

  37. Grant, P.W. (1968) Juvenile dermatitis herpetiformis. Trans. St. John’s Hosp. Dermatol. Soc., 54, 128–36.

    CAS  Google Scholar 

  38. Marsden, R.A. (1982) The treatment of benign chronic bullous dermatosis of childhood and bullous pemphigoid beginning in childhood. Clin. Exp. Dermatol., 7, 653–63.

    Article  PubMed  CAS  Google Scholar 

  39. Bürge, S., Wojnarowska, F. and Marsden, A. (1989) Chronic bullous dermatosis of childhood persisting into adulthood. Pédiatrie Dermatol., 5, 246–9.

    Article  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Marsden, R.A. (1990). Linear IgA disease of childhood (chronic bullous disease of childhood). In: Wojnarowska, F., Briggaman, R.A. (eds) Management of Blistering Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7190-6_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-7190-6_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-28990-3

  • Online ISBN: 978-1-4899-7190-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics