Advertisement

Genetic counselling and multiple handicap

  • I. D. Young

Abstract

Any couple who have had a child with a handicap must inevitably reflect on two fundamental questions. Why did it happen? Will it happen again? Everyone would agree that these two interrelated points warrant the fullest possible discussion, particularly if the degree of disability is severe to the extent that the child’s ability to live and enjoy a reasonably normal life is significantly impaired. In such a situation the possibility of recurrence will prompt most parents to think long and hard before embarking upon a subsequent pregnancy and it is only fair that they should be in full possession of the relevant facts before they attempt to reach a final decision about future childbearing.

Keywords

Genetic Counselling Down Syndrome Prenatal Diagnosis Club Foot Genetic Clinic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bundey, S. and Carter, C.O. (1974) Recurrence risks in severe undiagnosed mental deficiency. Mental Deficiency Res., 18, 115–34.Google Scholar
  2. Davies, K.E. (1986) Human Genetic Diseases. A Practical Approach, IRL Press, Oxford and Washington.Google Scholar
  3. Emery, A.E.H. (1984a) An Introduction to Recombinant DNA, John Wiley, Chichester.Google Scholar
  4. Emery, A.E.H. (1984b) The principles of genetic counselling, in (eds) A.E.H. Emery and I. Pullen Psychological Aspects of Genetic Counselling, Academic Press, London.Google Scholar
  5. Emery, A.E.H. Raeburn, J.A., Skinner, R., Holloway, S. and Lewis, P. (1979) Prospective study of genetic counselling. Br. Med. J., 1, 1253–6.PubMedCrossRefGoogle Scholar
  6. Gustayson, K.H., Hagberg, B., Hagberg, G. and Sars, K. (1977) Severe mental retardation in a Swedish county. II. Etiological and pathogenetic aspects of children born 1959–1970. Neuropädiatrie, 8, 293–304.CrossRefGoogle Scholar
  7. Harper, P.S. (1984) Practical Genetic Counselling, John Wright, Bristol. Hogg, J. and Lambe, L. (1988) Sons and Daughters with Profound Retarda-Education Centres: Final Report, Mencap, London.Google Scholar
  8. Laxova, R., Ridler, M.A.C. and Bowen-Bravery, M. (1977) An etiological survey of the severely retarded Hertfordshire children who were born between January 1, 1965 and December 31, 1967. Am. J. Med. Genet., 1, 75–86.PubMedCrossRefGoogle Scholar
  9. Opitz, J.M., Kaveggia, E.G., Durkin-Stamm, M.V. and Pendleton, E. (1978) Diagnostic/genetic studies in severe mental retardation. Birth Defects, Original Article Series, XIV, 6B, 1–38.Google Scholar
  10. Smithells, R.W., Nevin, N.C., Seller, M.J., Sheppard, S., Harris, R., Read, A.P., Fielding, D.W., Walker, S., Schorah, C.J. and Wild, J. (1983) Further experience of vitamin supplementation for prevention of neural tube defect recurrences. Lancet, 1, 1027–31.PubMedCrossRefGoogle Scholar
  11. Stene, J., Stene, E. and Mikkelsen, M. (1984) Risk for chromosome abnormality at amniocentesis following a child with a non-inherited chromosome aberration. Prenatal Diagnosis, Special Issue, 4, 81–95.Google Scholar
  12. Webb, T.P., Bundey, S., Thake, A. and Todd, J. (1986) The frequency of the fragile X chromosome among schoolchildren in Coventry. J. Med. Genet., 23, 396–9.PubMedCrossRefGoogle Scholar
  13. Winter, R.M., Baraitser, M. and Douglas, J.M. (1984) A computerised data base for the diagnosis of rare dysmorphic syndromes. J. Med. Genet., 21, 121–3.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1987

Authors and Affiliations

  • I. D. Young

There are no affiliations available

Personalised recommendations