Abstract
Phencyclidine, or PCP, chemically one of the arylcyclohexylamines, was originally developed as a dissociative anesthetic in the late 1950s. It was abandoned (for humans, but not other primates) in the mid 1960s because patients so often showed marked confusion and irrational behavior mimicking schizophrenia during postoperative recovery. Although PCP is the best known of about 30 psychoactive analogs, others, including PCE, TCP, PHP, PCC, and the shorter acting anesthetic, ketamine, are chemically related and have similar psychophysiological effects.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsFurther reading
Chasnoff IJ, Burns WJ, Hatcher RP, Burns KA (1983): Phencyclidine: Effects on the fetus and neonate. Dev Pharmacol Ther 6(6): 404–408
Clouet DH (1986): Phencyclidine: An Update, NIDA Reasearch Monograph, DHHS Publ No (ADM) 86–1443, Washington, D.C.: US Government Printing Office
Khansari N, Whitten HD, Fudenberg HH (1984): Phencylidineinduced immunodepression. Science 225(4657): 76–78
Petersen RC, Stillman RC, eds (1978): Phencyclidine (PCP) Abuse; An Appraisal, NIDA Research Monograph, DHEW Publ No (ADM) 78–728. Washington DC: US Government Printing Office
Walberg CB, McCarron MM, Schulze BN (1983): Quantitation of phencyclidine in serum by enzyme immunoassay: Results in 405 patients. J Anal Tox 7(2): 106–110
Rights and permissions
Copyright information
© 1989 Springer Science+Business Media New York
About this chapter
Cite this chapter
Petersen, R.C. (1989). Phencyclidine. In: Abnormal States of Brain and Mind. Readings from the Encyclopedia of Neuroscience . Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4899-6768-8_38
Download citation
DOI: https://doi.org/10.1007/978-1-4899-6768-8_38
Publisher Name: Birkhäuser, Boston, MA
Print ISBN: 978-1-4899-6770-1
Online ISBN: 978-1-4899-6768-8
eBook Packages: Springer Book Archive