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Nicotinic Acetylcholine Receptors in the Human Nervous System

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Cholinergic Basis for Alzheimer Therapy

Part of the book series: Advances in Alzheimer Disease Therapy ((AADT))

Abstract

Nicotinic acetylcholine receptors (AChR) are key molecules that mediate chemical communications between cells in various parts of the body: at the neuromuscular junction, in autonomic ganglia and in several areas of the brain. The activation of AChR by the acetylcholine (ACh) released from nerve terminals induces an influx of cations, mainly Na+ ions, through the cell membrane, consequently depolarizing the target cell.

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Chini, B., Tarroni, P., Rubboli, F., Raimondi, E., Clementi, F. (1991). Nicotinic Acetylcholine Receptors in the Human Nervous System. In: Becker, R., Giacobini, E. (eds) Cholinergic Basis for Alzheimer Therapy. Advances in Alzheimer Disease Therapy. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4899-6738-1_12

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  • DOI: https://doi.org/10.1007/978-1-4899-6738-1_12

  • Publisher Name: Birkhäuser, Boston, MA

  • Print ISBN: 978-1-4899-6740-4

  • Online ISBN: 978-1-4899-6738-1

  • eBook Packages: Springer Book Archive

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