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The Fungal Cell Wall — A Target For Lipopeptide Antifungal Agents

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New Approaches for Antifungal Drugs

Abstract

There are two key factors that justify the search for safer and more effective antifungal agents for human medicine. First, the currently available antifungal therapy, especially for life-threatening disseminated fungal infections, is not satisfactory because of limited efficacy and/or toxicity (Graybill, 1989). Second, there is an increased incidence of fungal infections attributed to the aggressive use of cancer chemotherapy, organ transplantation, and opportunistic infections associated with acquired immunodeficiency syndrome (AIDS) patients (Patterson and Andriole, 1989).

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Authors
  1. Robert S. Gordee
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  2. Manuel Debono
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  3. Thomas R. Parr Jr.
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Editor information

Editors and Affiliations

  1. Department of Microbial Molecular Biology, Bristol Myers Squibb Pharmaceutical Research Institute, 08543, Princeton, New Jersey, USA

    Prabhavathi B. Fernandes

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Gordee, R.S., Debono, M., Parr, T.R. (1992). The Fungal Cell Wall — A Target For Lipopeptide Antifungal Agents. In: Fernandes, P.B. (eds) New Approaches for Antifungal Drugs. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4899-6729-9_4

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  • DOI: https://doi.org/10.1007/978-1-4899-6729-9_4

  • Publisher Name: Birkhäuser, Boston, MA

  • Print ISBN: 978-1-4899-6731-2

  • Online ISBN: 978-1-4899-6729-9

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