Abstract
During the past decade the influence of muscle length on the contractile performance has assessed much interest. However it has been known for a much longer time that ventricular volume, and therefore cardiac muscle length, is uniquely related to ventricular performance (Starling, 1918). This was based on the idea that change of muscle length only induces a change in geometry within the myofilaments and not in the inotropic state of the muscle itself. Investigations on this subject reveal that this separability of inotropic state and geometric factors of a muscle cannot be demonstrated. Schamhardt and De Beer (1980) showed that the time course of pressure and first time derivative of pressure are influenced in the same way by inotropic changes as well as by volume changes. In their study, the change in volume was carried out in diastole over a relatively long period before stimulation of the ventricle.
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© 1982 Springer Science+Business Media New York
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Schiereck, P. (1982). Stretch Induced Activation and Deactivation in Intact Left Ventricles. In: Kenner, T., Busse, R., Hinghofer-Szalkay, H. (eds) Cardiovascular System Dynamics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-6693-3_7
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DOI: https://doi.org/10.1007/978-1-4899-6693-3_7
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