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Effect of Type of Diet on Cholesterol Absorption and Bile Salt Excretion in Germfree and Conventional Chicks

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Book cover Germ-Free Biology Experimental and Clinical Aspects

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 3))

Abstract

It has been a rather common observation that serum cholesterol levels of animals fed commercial or practical type diets are lower than those of animals fed purified diets. Although several studies (1, 2) support the hypothesis that the hypocholesterolemic effect of practical type diets could be due to acceleration of the turnover of bile acids, it is not clear whether the intestinal microflora play a role in these phenomena. In the experiments of Portman (3), addition to the diet of suecinylsulfathiazole reduced the effect of Purina rat chow on bile acid turnover by approximately 50 %. On the other hand, Wostmann and Kan (4) concluded that the cholesterol-lowering effect of Purina chow was independent of the microflora since it also occurred in germfree rats.

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References

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Author information

Authors and Affiliations

  1. The Rega Institute, University of Leuven, Minderbroedersstraat, 10, Leuven, Belgium

    H. Eyssen, G. Van Messom & J. Van den Bosch

Authors
  1. H. Eyssen
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  2. G. Van Messom
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  3. J. Van den Bosch
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Editor information

Editors and Affiliations

  1. Roswell Park Memorial Institute, New York State Department of Health, State University of New York, Buffalo, New York, USA

    Edwin A. Mirand

  2. Canisius College, Niagara University, Niagara University, New York, Buffalo, New York, USA

    Edwin A. Mirand

  3. Department of Biochemical Pharmacology, School of Pharmacy, State University of New York, Buffalo, New York, USA

    Nathan Back

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© 1969 Springer Science+Business Media New York

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Eyssen, H., Van Messom, G., Van den Bosch, J. (1969). Effect of Type of Diet on Cholesterol Absorption and Bile Salt Excretion in Germfree and Conventional Chicks. In: Mirand, E.A., Back, N. (eds) Germ-Free Biology Experimental and Clinical Aspects. Advances in Experimental Medicine and Biology, vol 3. Springer, New York, NY. https://doi.org/10.1007/978-1-4899-6495-3_11

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  • DOI: https://doi.org/10.1007/978-1-4899-6495-3_11

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4899-6234-8

  • Online ISBN: 978-1-4899-6495-3

  • eBook Packages: Springer Book Archive

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