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Bacterial Burden and Wound Repair in Conventional and Germfree Rats

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Germ-Free Biology Experimental and Clinical Aspects

Abstract

It is generally agreed that gross infection is detrimental to the wound repair processes, however, the significance of wound contamination with bacteria without the ensuing clinical signs of infection is largely unknown. It is likely that most cutaneous wounds in conventional animals are inevitably contaminated at operation or shortly thereafter. Bacterial contamination does not guarantee that infection will follow, but infection does not occur in the absence of bacteria (Casten et al, 1964).

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References

  1. Casten, D. F., R.J. Nach, J. Spinzia, Surg. Gyn. Obst. 118, 783 (1964).

    CAS  PubMed  Google Scholar 

  2. Ryan, E.A., Brit. J. Surg. 54, 324 (1957).

    Article  Google Scholar 

  3. Rovee, D.T., C.A. Kurowsky, P.A. Flanagan, In Preparation (1968).

    Google Scholar 

  4. Geever, E.F., S. Youssef, E. Seifter, S.M. Levenson, J. Surg. Res. 7, 160 (1967f).

    Article  CAS  Google Scholar 

  5. Seifter, E., J. J. Morris, S.M. Levenson, Nature 217, 1055 (1968).

    Article  CAS  Google Scholar 

  6. Scapicchio, A.P., J.D. Constable, B. Opitz, Plast. Recon str. Surg. 41, 319 (1968).

    Article  CAS  Google Scholar 

  7. Miyakawa, M., in Recent Progress in Microbiology (Charles C. Thomas, Publisher, Springfield, Illinois, 1959), p.299.

    Google Scholar 

  8. Tipton, J.E. and R. O. Dingman, Plast. Reconstr. Surg. 38, 499 (1966).

    Article  CAS  Google Scholar 

  9. Rovin, S., E.R. Costich, J.E. Fleming, H.A. Gordon, Arch. Path. 79, 641 (1965).

    CAS  PubMed  Google Scholar 

  10. Brody, G.L., J.E. Bishop, G.D. Abrams, Arch. Path. 8l, 268 (1966).

    Google Scholar 

  11. Luckey, T.L., Germfree Life and Gnotobiology (Academic Press, New York, 1963).

    Google Scholar 

  12. Winter, G.D., Nature 193, 293 (1962).

    Article  CAS  Google Scholar 

  13. Hinman, C.D. and H.I. Maibach, Nature 200, 377 (1963).

    Article  CAS  Google Scholar 

  14. Rovee, D.T. and C.A. Miller, Arch. Surg. 96, 43 (1968).

    Article  CAS  Google Scholar 

  15. Gimbel, N.S. and W. Farris, Arch. Surg. 92, 554 (1966).

    Article  CAS  Google Scholar 

  16. Filston, H. C. and G.J. Vennes, Surg. Gyn. Obst. 126, 572 (1968).

    PubMed  Google Scholar 

  17. Culbertson, D.P. and W.J. Tilston, Quart. J. Exp. Physiol. 52, 249 (1967).

    Article  Google Scholar 

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© 1969 Springer Science+Business Media New York

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Rovee, D.T., Kurowsky, C.A., Flanagan, P.A. (1969). Bacterial Burden and Wound Repair in Conventional and Germfree Rats. In: Mirand, E.A., Back, N. (eds) Germ-Free Biology Experimental and Clinical Aspects. Advances in Experimental Medicine and Biology, vol 3. Springer, New York, NY. https://doi.org/10.1007/978-1-4899-6495-3_10

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  • DOI: https://doi.org/10.1007/978-1-4899-6495-3_10

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4899-6234-8

  • Online ISBN: 978-1-4899-6495-3

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