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Antibiotics, Animals, and the Resistance Gene Pool

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Book cover The Antibiotic Paradox

Abstract

Of the six billion animals raised for human consumption in the United States yearly, most receive some antibiotics during their short lifetimes. In any one year, domestic food animals outnumber humans in the United States by more than five to one. These figures are important when we assess the effect that antibiotics have on the bacterial flora of these animals that not only share our environment, but also end up in our stomachs.

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References

References Cited

  1. Pritchard, W. R. and Loew, F. M., Veterinary Medicine: Looking toward the 21st century. In: Perspectives on the Health Professions. Chapter 1. (O’Neil, E. H., Ed.). Pew Health Professions Programs, Duke University, 1990.

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Bibliography Chapter 6

  • Anderson, E. S. and Lewis, M. J. Characterization of a transfer factor associated with drug resistance in Salmonella typhimurium. Nature 208:843–849, 1965.

    Article  PubMed  CAS  Google Scholar 

  • Edel, W., Van Schothorsat, M., Van Leusden, F. M. and Kampelmacher, E.H. Epidemiological studies on Salmonella in a certain area. Zbl. Bakt Hyg. I. Abt. Orig. A 242:468–480, 1978.

    CAS  Google Scholar 

  • Holmberg, S. D. et al. Drug resistant Salmonella from animals fed antibiotics. N. Engl. J. Med. 311:617–622, 1987.

    Article  Google Scholar 

  • Hummel, R., Tschape, H., and Witte, W. Spread of plasmid-mediated nourseothricin resistance in connection with antibiotic use in animal husbandry. J. Basic Microb. 26:461–466, 1986.

    Article  CAS  Google Scholar 

  • Levy, S. B. Antibiotic use for growth promotion in animals: ecologic and public health consequences. J. Food Protection 50:616–620, 1987.

    Google Scholar 

  • Levy, S. B., Fitzgerald, G. G. and Macone, A. B. Changes in the intestinal flora of farm personnel after introduction of tetracycline-supplemented feed on a farm. N. Engl. J. Med. 295:583–588, 1976.

    Article  PubMed  CAS  Google Scholar 

  • Lyons, R. W., Samples, C. L., DeSilva, H. N. et al. An epidemic of resistant Salmonella in a nursery: animal-to-animal spread. J. Amer. Med. Assoc. 243:546–547, 1980.

    Article  CAS  Google Scholar 

  • Marshall, B. M., Petrowski, D., and Levy, S. B. Inter and intraspecies spread of E. coli in a farm environment in the absence of antibiotic usage. Proc. Nat’l Acad. Sci. (USA) 87:6609–6613, 1990.

    Article  CAS  Google Scholar 

  • Riley, L. W. et al. Evaluation of isolated cases of salmonellosis by plasmid profile analysis: introduction and transmission of a bacterial clone by precooked roast beef. J. Infect. Dis. 148:12–17, 1983.

    Article  PubMed  CAS  Google Scholar 

  • Riley, L. W. et al. Importance of host factors in human salmonella caused by multiresistant strains of Salmonella. J. Infect. Dis. 149:878–883, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Ryan, C. A., Nickels, M. K. et al. Massive outbreak of antimicrobial-resistant salmonellosis traced to pasteurized milk. J. Amer. Med. Assoc. 258:3269–3279, 1987.

    Article  CAS  Google Scholar 

  • Schifferli, D. M. and Beachey, E. H. Bacterial adhesion: modulation by antibiotics which perturb protein synthesis. Antimicrob. Agents Chemother. 32:1603–1608, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Spika, J. S., Waterman, S. H., Soo Hoo, G. W. et al. Chloramphenicol-resistant Salmonella newport traced through hamburger to dairy farms. N. Engl. J. Med. 316:565–580, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Stokstad, E. L. R. and Jukes, T. H. Further observations on the “animal protein factor.” Proc. Soc. Exp. Biol. Med. 73:523–528, 1950.

    Article  CAS  Google Scholar 

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© 1992 Stuart B. Levy

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Levy, S.B. (1992). Antibiotics, Animals, and the Resistance Gene Pool. In: The Antibiotic Paradox. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-6042-9_6

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  • DOI: https://doi.org/10.1007/978-1-4899-6042-9_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-44331-2

  • Online ISBN: 978-1-4899-6042-9

  • eBook Packages: Springer Book Archive

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