Skip to main content

Screening of Antineoplastic Agents with Neurospora Crassa

  • Chapter
Developments in Industrial Microbiology

Abstract

The author of this presentation has not participated in the screening program of biological beers. He has, however, analyzed chemically defined compounds and microbial systems employed in the testing of both potential and established Chemotherapeutic agents.

This work was supported by the National Institutes of Health, Research Grant CY3853(C2).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Biesele, John J. and Jacquez, John A. 1954 Mitotic effects of certain amino acid analogs in tissue culture. Annals of the New York Academy of Sciences, 58, 1276–1287.

    Article  PubMed  CAS  Google Scholar 

  • Foley, G.E., McCarthy, R. E., Binns, V.M., Snell, E.E., Guirard, B.M., Kidder, G.W., Dewey, V. C., and Thayer, P. S. 1958 A comparative study of the use of microorganisms in the screening of potential antitumor agents. Annals of the New York Academy of Sciences, 76, 412–441.

    Article  Google Scholar 

  • Fuerst, R., and Higgins, R. W. The biology of some thiophene compounds. In Preparation.

    Google Scholar 

  • Fuerst, R., Hsu, T. C., and Somers, C.D. 1956 Neurospora crassa as an assay organism for antimetabolites. Bact. Proc., 32.

    Google Scholar 

  • Fuerst, R., and Skellenger, W.M. 1958 A Neurospora plate method for testing antimetabolites. Antibiotics & Chemotherapy, 8, 76–80.

    CAS  Google Scholar 

  • Fuerst, R., Somers, C. E., and Hsu, T. C. 1956 Studies on 4-aminopyrazolo(3,4-d)pyrimidine: growth inhibition and relief in Neurospora crassa. J. Bact., 72, 387–393.

    PubMed  CAS  Google Scholar 

  • Hsu, T. C., Robins, R. K., and Cheng, C. C. 1956 Studies on 4-APP: antineoplastic action in vitro. Science, 123, 848–849.

    Article  PubMed  CAS  Google Scholar 

  • Rhoads, C. P., Ed. 1955 Antimetabolites and Cancer: A Symposium. Annals of the New York Academy of Sciences, 89–105.

    Google Scholar 

  • Robins, R. K. 1956 Potential purine antagonists. I. Synthesis of some 4,6-substitutedpy-razolo(3,4-d)pyrimidines. J. Am. Chem. Soc., 78, 784–790.

    Article  CAS  Google Scholar 

  • Somers, C. E., Fuerst, R., and Hsu,T. C. 1957 Studies on 4-aminopyrazolo(3,4-d) pyrimidine: structural relationships among inhibiting and relieving agents in Neurospora Antibiotics Chemotherapy, 7, 363–373.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1960 Springer Science+Business Media New York

About this chapter

Cite this chapter

Fuerst, R. (1960). Screening of Antineoplastic Agents with Neurospora Crassa . In: Developments in Industrial Microbiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-5073-4_15

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-5073-4_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-5075-8

  • Online ISBN: 978-1-4899-5073-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics