Extensions and alternatives

Abstract

We have seen in Chapter 2 that the basic characteristic of standard quantal assay data is that of binomial response variables, with probability of response modelled as a monotonic increasing function of dose. Several of the examples of Chapter 1 are similar to this pattern, but they need a variety of elaborations to the basic model. Some of these require extensive discussion and so are dealt with at length in later chapters. It is the aim of this chapter to cover the simpler extensions and alternative approaches. For the most part we shall deal with them singly, but of course for any particular problem they may appear in combination. Inevitably, the sections of this chapter will not follow each other in the same logical sequence as in the other chapters of the book.