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Familial ovarian cancer

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Genetic Predisposition to Cancer

Abstract

The lifetime risk of epithelial ovarian cancer for a woman in the UK is about 1 in 80. Some families in which there are two ovarian cancers, or an ovarian cancer and another common cancer at a young age in close relatives will be expected to occur by chance. However, population-based epidemiological studies show that there is a significant excess risk of cancer at several sites in the relatives of ovarian cancer patients (Table 19.1). This familial clustering must arise from some combination of inherited and environmental effects.

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© 1996 Springer Science+Business Media Dordrecht

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Ponder, B.A.J. (1996). Familial ovarian cancer. In: Eeles, R.A., Ponder, B.A.J., Easton, D.F., Horwich, A. (eds) Genetic Predisposition to Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-4501-3_19

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  • DOI: https://doi.org/10.1007/978-1-4899-4501-3_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-56580-9

  • Online ISBN: 978-1-4899-4501-3

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