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Nonlinear Dynamics and Ionic Mechanisms of Excitation Patterns in Models of the Cardiac Myocyte

  • Alain Vinet
  • Dante R. Chialvo
  • Donald C. Michaels
  • Jose Jalife
Chapter
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Part of the NATO ASI Series book series (NSSB, volume 244)

Abstract

Ventricular arrhythmias are spatial phenomena which result from one or more activation fronts travelling at a given time across the cardiac muscle. Two basic mechanisms have been postulated for the genesis and/or perpetuation of such depolarization wavefronts: (i) the activity of local pacemakers, referred to as ectopic foci [23, 24]; and (ii) the formation of reentrant circuits, whereby the wavefront circles around an electrically excitable ventricular pathway [24]. Both mechanisms require that individual excitable cells involved in the arrhythmias be able to sustain high frequency pacing, and both mechanisms demand a description of the phase-locking behaviour of such cells when subjected to external driving.

Keywords

Lyapunov Exponent Cardiac Cell Parameter Plane Repetitive Stimulation Bifurcation Structure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Alain Vinet
    • 1
  • Dante R. Chialvo
    • 1
  • Donald C. Michaels
    • 1
  • Jose Jalife
    • 1
  1. 1.State University of New York Health Science CenterSyracuseUSA

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