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Developments in Analytical Methods in Pharmaceutical, Biomedical, and Forensic Sciences pp 247–256Cite as

Application of a Solid Phase Autosampler to the HPLC Determination of Drugs and Natural Compounds in Biological Matrices

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Abstract

The use of a sample cleanup and extraction device and a column switching technique allowed us to propose an automatized method for the determination of plasma xanthines1.

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References

  1. G. Grossi, A. Bargossi, G. Righi, R. Pasquali, R. Battistoni and A. Lippi, Estrazione in fase solida ed analisi in HPLC delle xantine mediante un sistema completamente automatizzato, Biochim. Clin. 9: 1037 (1985).

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  2. P.J. Naish and M. Cooke, Rapid assay for theophylline in clinical samples by reversed-phase high-performance liquid chromatography, J. Chromatogr. 163: 363 (1979).

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  4. R.W. Frei, New sample handling strategies in HPLC, Swiss. Chem. 6: 55 (1984).

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  5. G. Grossi, A. Bargossi, Estrazione in fase solida ed analisi in HPLC delle xantine mediante un sistema completamente automatizzato, Biochim. Clin. 9: 1037 (1985).

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  6. G. Grossi, Urinary homovanillic acid and vanilmandelic acid: solid phase extraction and determination by high-performance liquid chromatography with electrochemical detection, in: Proceedings of the Conference “La Cromatografia Liquida ad Elevata Risoluzione (HPLC) in Analitica Clinica: Situazione Attuale e Prospettive”, Verona, July 1–2, Cortina, Verona, in press.

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  7. G. Grossi, Determination of catecholamines in plasma and urine by high-performance liquid chromatography: a comparison among different extraction, separation and detection methods, in: Proceedings of the Conference “La Cromatografia Liquida ad Elevata Risoluzione (HPLC) in Analitica Clinica: Situazione Attuale e Prospettive”, Verona, July 1–2, Cortina, Verona, in press.

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Author information

Authors and Affiliations

  1. Clinical Chemistry Laboratory, “St. Orsola” Hospital, Bologna, Italy

    G. Grossi, A. Bargossi, R. Callivà, M. G. Salvatore, R. Battistoni & A. Lippi

Authors
  1. G. Grossi
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  2. A. Bargossi
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  3. R. Callivà
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  4. M. G. Salvatore
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  5. R. Battistoni
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  6. A. Lippi
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Editor information

Editors and Affiliations

  1. University of Verona, Verona, Italy

    G. Piemonte , F. Tagliaro  & M. Marigo ,  & 

  2. Italian Group for Mass Spectrometry in Biochemistry and Medicine, Milan, Italy

    A. Frigerio

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© 1987 Springer Science+Business Media New York

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Grossi, G., Bargossi, A., Callivà, R., Salvatore, M.G., Battistoni, R., Lippi, A. (1987). Application of a Solid Phase Autosampler to the HPLC Determination of Drugs and Natural Compounds in Biological Matrices. In: Piemonte, G., Tagliaro, F., Marigo, M., Frigerio, A. (eds) Developments in Analytical Methods in Pharmaceutical, Biomedical, and Forensic Sciences. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3526-7_28

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  • DOI: https://doi.org/10.1007/978-1-4899-3526-7_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-3528-1

  • Online ISBN: 978-1-4899-3526-7

  • eBook Packages: Springer Book Archive

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