Abstract
Since the application of t.-butyldimethylsilyl (t.BDMSi) ether derivatives to the GC-MS analysis of steroids by Kelly and Taylor1 in 1974, this silylation has been widely used in the selective detection of hydroxylated steroids2–22.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
R.W. Kelly and P.L. Taylor, in: Summaries of the Proceedings of the 2nd International Symposium on Mass Spectrometry in Biochemistry and Medicine, Milan, Italy, 51, June (1974).
R.W. Kelly and P.L. Taylor, Anal. Chem. 48: 465 (1976).
S.J. Gaskell and C.J.W. Brooks, Biochem. Soc. Trans., 560th Meet. 4: 111 (1976).
D.S. Millington, J. Steroid Biochem. 6: 239 (1975).
G. Phillipou, D.A. Bigham and R.F. Seamark, Steroids 26: 516 (1975).
A.G. Smith, S.J. Gaskell and C.J.W. Brooks, Biomed. Mass Spectrom. 3: 161 (1976).
B.P. Lisboa and J.McK. Halket, in: A. Frigerio ed., Recent Developments in Mass Spectrometry in Biochemistry and Medicine, Vol.1, Plenum Publishing Corp., New York, 441 (1978).
M.A. Quilliam and J.B. Westmore, Anal. Chem. 50: 59 (1978).
B.P. Lisboa and J. McK Halket, in: A. Frigerio and L. Renoz eds., Recent Developments in Chromatography and Electrophoresis, Elsevier, Amsterdam, 141 (1979).
S.J. Gaskell, A.W. Pike and D.S. Millington, Biomed. Mass Spectrom. 6: 78 (1979).
B.P. Lisboa and I. Ganschow, in: A. Frigerio ed., Chromatography and Mass Spectrometry in Biomedical Sciences, Vol. 2, Elsevier, Amsterdam, 291 (1983).
M.A. Quilliam and J.B. Westmore, Steroids 29: 579 (1977).
R.W. Kelly and P.L. Taylor, in: A. Frigerio and N. Castagnoli, eds., Advances in Mass Spectrometry in Biochemistry and Medicine, Vol. 1, Spectrum Publications, New York, 449 (1976).
S.H.G. Andersson and J. Sjoevall, J. Chromatogr. 289: 195 (1984).
S.J. Gaskell and A.W. Pike, Biomed. Mass Spectrom. 8: 125 (1981).
L. Ballhorn, W.F. Mueller and F. Korte, Steroids 33: 379 (1979).
A.G. Sharkey jr., R.A. Friedel and S.H. Langer, Anal. Chem. 29: 770 (1957).
J.A. Gustafsson, Arkiv foer Kemi 29: 535 (1968).
B.P. Lisboa and J.A. Gustafsson, Eur. J. Biochem. 9: 402 (1969).
J.A. Gustafsson and B.P. Lisboa, Acta Endocr. 65: 84 (1970).
J.A. Gustafsson and B.P. Lisboa, Steroids 15: 723 (1970).
S.L. Dale and J.C. Melby, Steroids 21: 617 (1973).
C.J.W. Brooks and D.J. Harvey, Steroids 15: 283 (1970).
M.A. Quilliam, J.F. Templeton and J.B. Westmore, Steroids 29: 613 (1977).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Springer Science+Business Media New York
About this chapter
Cite this chapter
Lisboa, B.P. (1987). Methoxyimino-tert-Butyldimethylsilyl Ethers as Derivatives for the Gas Chromatography-Mass Spectrometry of 3 (or 17)-Hydroxy-C19 — and 20-Hydroxy-C21-Ketosteroids. In: Piemonte, G., Tagliaro, F., Marigo, M., Frigerio, A. (eds) Developments in Analytical Methods in Pharmaceutical, Biomedical, and Forensic Sciences. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3526-7_22
Download citation
DOI: https://doi.org/10.1007/978-1-4899-3526-7_22
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-3528-1
Online ISBN: 978-1-4899-3526-7
eBook Packages: Springer Book Archive