Skip to main content

Determination of Morphine and Other Opioids in the Hair of Heroin Addicts by RIA, HPLC and Collisional Spectroscopy

  • Chapter
Developments in Analytical Methods in Pharmaceutical, Biomedical, and Forensic Sciences

Abstract

The determination of morphine in the hair, according to several Authors’ reports, could become a useful tool for identifying past, chronic heroin intake.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. A.M. Baumgartner, P.F. Jones, W.A. Baumgartner and C.T. Black, Radioimmunoassay of hair for determining opiate-abuse histories J. Nucl. Med. 20: 748 (1979).

    PubMed  CAS  Google Scholar 

  2. D. Valente, M. Cassani, M. Pigliapochi and G. Vanzetti, Hair as the sample in assessing morphine and cocaine addiction, Clin. Chem. 27: 1952 (1981).

    PubMed  CAS  Google Scholar 

  3. A. Carnevale, M. Marchetti and A. Fiori, La ricerca radioimmunologica della morfina nei capelli, Boll. Farmacod. Alcoolismo 6: 579 (1983).

    Google Scholar 

  4. K. Puschel, P. Thomasch and W. Arnold, Opiate levels in hair, Forens. Sci. Int. 21: 181 (1983).

    Article  CAS  Google Scholar 

  5. F. Black, in: “Methods of Morphine Estimation in Biological Fluids and the Concept of Free Morphine”, J.F.B. Stuart, ed, The Royal Society of Medicine, London (1983).

    Google Scholar 

  6. I. Jane and F. Taylor, Characterization and quantitation of morphine in urine using high-pressure liquid chromatography with fluorescence detection, J. Chromatogr. 109: 37 (1975).

    PubMed  CAS  Google Scholar 

  7. J.E. Wallace, S.C. Harris and M.W. Peek, Determination of morphine by liquid chromatography with electrochemical detection, Anal. Chem. 52: 1328 (1980).

    Article  PubMed  CAS  Google Scholar 

  8. B.L. Posey and S.N. Kimble, Simulteneous determination of codeine and morphine in urine and blood by HPLC, J. Anal. Toxicol. 7: 241 (1983).

    Article  PubMed  CAS  Google Scholar 

  9. F. Tagliaro, A. Frigerio, R. Dorizzi, G. Lubli and M. Marigo, Liquid chromatography with pre-column dansyl derivatization and fluorimetric detection applied to the assay of morphine in biological samples, J. Chromatogr. 330: 323 (1985).

    Article  PubMed  CAS  Google Scholar 

  10. M. Marigo, F. Tagliaro, C. Poiesi, S. Lafisca and C. Neri, Determination of morphine in the hair of heroin addicts by High Performance Liquid Chromatography with fluorimetric detection, J. Anal. Toxicol. 10: 158 (1986).

    Article  PubMed  CAS  Google Scholar 

  11. B. Pelli, P. Traldi, F. Tagliaro, G. Lubli and M. Marigo, Collisional spectroscopy for inequivocal and rapid determination of morphine at ppb level in the hair of heroin addicts, Biomed. Mass Spectrom. 14: 63 (1987).

    Article  CAS  Google Scholar 

  12. R.W. Frei, W. Santi and M. Thomas, Liquid chromatography of dansyl derivatives of some alkaloids and the application to the analysis of Pharmaceuticals, J. Chromatogr. 116: 365 (1976).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Springer Science+Business Media New York

About this chapter

Cite this chapter

Tagliaro, F., Traldi, P., Pelli, B., Maschio, S., Neri, C., Marigo, M. (1987). Determination of Morphine and Other Opioids in the Hair of Heroin Addicts by RIA, HPLC and Collisional Spectroscopy. In: Piemonte, G., Tagliaro, F., Marigo, M., Frigerio, A. (eds) Developments in Analytical Methods in Pharmaceutical, Biomedical, and Forensic Sciences. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3526-7_14

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-3526-7_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-3528-1

  • Online ISBN: 978-1-4899-3526-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics