Abstract
In the recent years the determinations of drugs in biological fluids were not only carried out in serum, plasma and urine, but also in other specimens such as saliva, milk, spinal fluid etc. The saliva drug levels are of special interest, because its concentration values correlate with plasma levels. Saliva offers particular advantages in various application areas, such as:
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1.
bioavailability and pharmacokinetic studies;
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2.
therapeutic drug monitoring;
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3.
forensic and epidemiological monitoring of drugs of abuse.
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© 1987 Springer Science+Business Media New York
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Mari, F., Bertol, E., Biagioli, R., Chiarugi, R. (1987). Saliva/Plasma Ratios for Forensic Monitoring of Drug Assumption in Opiate Addicts. In: Piemonte, G., Tagliaro, F., Marigo, M., Frigerio, A. (eds) Developments in Analytical Methods in Pharmaceutical, Biomedical, and Forensic Sciences. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3526-7_12
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DOI: https://doi.org/10.1007/978-1-4899-3526-7_12
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