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Management of Mycobacterial Infections in AIDS

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Abstract

The treatment of tuberculosis in association with HIV is essentially not different from that of patients without HIV infection and follows well-established principles. The choice of chemotherapy regimen may be limited by cost or toxicity or be influenced by the likelihood of multiple drug resistance. Because patients with HIV are likely to be immunosuppressed and to become more so with time, there is some debate about whether one or more drugs should be continued after completing a course of treatment. As patients with HIV are more likely to relapse or acquire new infection, preventive therapy for life may be desirable. In areas of high prevalence of HIV and tuberculosis (as in Sub-Saharan Africa), tuberculosis remains the major cause of death in AIDS (Kassim et al., 1995). Strategies for chemoprophylaxis in these high risk groups must be considered.

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Authors
  1. Geoff M. Scott
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  2. Janet H. Darbyshire
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Editors and Affiliations

  1. Department of Medicine, University College London Medical School, London, UK

    Alimuddin Zumla BSc MB ChB MSc PhD FRCP (Director, Visiting Professor, Honorary Consultant in Infectious Diseases) (Director, Visiting Professor, Honorary Consultant in Infectious Diseases)

  2. Camden and Islington Community Health Services NHS Trust, London, UK

    Alimuddin Zumla BSc MB ChB MSc PhD FRCP (Director, Visiting Professor, Honorary Consultant in Infectious Diseases) (Director, Visiting Professor, Honorary Consultant in Infectious Diseases)

  3. Department of Medicine, University of Zambia School of Medicine, Lusaka, Zambia

    Alimuddin Zumla BSc MB ChB MSc PhD FRCP (Director, Visiting Professor, Honorary Consultant in Infectious Diseases) (Director, Visiting Professor, Honorary Consultant in Infectious Diseases)

  4. Department of Respiratory Medicine, The Royal Free Hospital, London, UK

    Margaret Johnson MD, FRCP (Consultant Physician) (Consultant Physician)

  5. Department of Sexually Transmitted Diseases, Division of Pathology and Infectious Diseases, University College London Medical School, London, UK

    Robert Miller MB FRCP (Senior Lecturer/Honorary Consultant Physician, Honorary Consultant Physician) (Senior Lecturer/Honorary Consultant Physician, Honorary Consultant Physician)

  6. Camden and Islington Community Health Services NHS Trust, London, UK

    Robert Miller MB FRCP (Senior Lecturer/Honorary Consultant Physician, Honorary Consultant Physician) (Senior Lecturer/Honorary Consultant Physician, Honorary Consultant Physician)

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© 1997 Springer Science+Business Media Dordrecht

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Scott, G.M., Darbyshire, J.H. (1997). Management of Mycobacterial Infections in AIDS. In: Zumla, A., Johnson, M., Miller, R. (eds) AIDS and Respiratory Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3446-8_12

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  • DOI: https://doi.org/10.1007/978-1-4899-3446-8_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-60140-8

  • Online ISBN: 978-1-4899-3446-8

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