Abstract
Depression is one of the most common symptoms presented by the elderly (Kantor and Glassman, 1980). Depressive illness is a recurrent condition in 60% of cases and usually presents for the first time in the 40s. Depression in the older age group consists of patients whose illness arose earlier in life and persists until the older ages, and patients in whom depression presents for the first time in late life after 70.
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References
Abou-Saleh, M.T. and Coppen, A. (1983). Subjective side-effects of amitriptyline and lithium in affective disorders. Br. J. Psychiat., 142, 527–8.
Abou-Saleh, M.T. and Coppen, A. (1983b) Classification of depression and response to antidepressive therapies. Br. J. Psychiat., 143, 601–3.
Angst, J., Weis, P. and Grof, P. (1970) Lithium prophylaxis in recurrent affective disorders. Br. J. Psychiat., 116, 604–14.
Angst, J. (1981) Clinical indications for a prophylactic treatment of depression. Adv. Biol. Psychiat., 7, 218–29.
Baastrup, P. and Schou, M. (1967) Lithium as a prophylactic agent: its effect against recurrent depressions and manic-depressive psychosis. Arch. Gen. Psychiat., 16, 162–72.
Baastrup, P., Poulsen, J.C. and Schou, M. (1970) Prophylactic lithium. Double-blind discontinuation in manic depressive and recurrent depressive disorders. Lancet, ii, 326–30.
Carney, M.H.P., Roth, M. and Garside, R.F. (1965) The diagnosis of depressive syndromes and the prediction of ECT response. Br. J. Psychiat., 111, 659–74.
Coppen, A. and Abou-Saleh, M.T. (1983) Lithium in the prophylaxis of unipolar depression. J. Roy. Soc. Med., 76, 297–301.
Coppen, A., Abou-Saleh, M.T., Milln, P. et al. (1981) Lithium continuation therapy following ECT. Br. J. Psychiat., 139, 284–7.
Coppen, A., Abou-Saleh, M.T., Milln, P. et al. (1983) Decreasing lithium dosage reduces morbidity and side-effects during prophylaxis. J. Affect. Disord., 5, 353–62.
Coppen, A., Chaudhury, S. and Swade, C. (1986) Folic acid enhances lithium prophylaxis. J. Affect. Disord., 10, 9–13.
Coppen, A., Ghose, K., Montgomery, S. et al. (1978a) Continuation therapy with amitriptyline in depression. Brit. J. Psychiat., 133, 28–33.
Coppen, A., Ghose, K., Rao, V.A.R. et al. (1978b) Mianserin and lithium in the prophylaxis of depression. Br. J. Psychiat., 133, 206–10.
Coppen, A., Metcalfe, M. and Bailey, J. (1979) Lithium prophylactic therapy in unipolar depression and some possible prognostigators of response. In: Lithium Controversies and Unresolved Issues (eds. T.B. Cooper, S. Gershon, N.S. Kline and M. Scholl), Excerpta Medica, Amsterdam, pp. 401–12.
Coppen, A., Montgomery, S.A., Gupta, R.K. and Bailey, J. (1976) A double-blind comparison of lithium carbonate and maprotiline in the prophylaxis of affective disorders. Br. J. Psychiat., 128, 479–85.
Coppen, A., Noguera, R., Bailey, J. et al. (1971) Prophylactic lithium in affective disorders — controlled trial. Lancet, ii, 275–9.
Eysenck, H.J. and Eysenck, S.B.G. (1964) Manual of Eysenck Personality Inventory, University of London Press, London.
Fieve, R.R., Dunner, D.L. and Kumbarachi, T. (1975) Lithium carbonate in affective disorders. Arch. Gen. Psychiat., 32, 1541–4.
Ghose, K. (1977) Lithium salts: therapeutic and unwanted effects. Br. J. Hosp. Med., 18, 578–83.
Glen, A. (1981) Lithium and antidepressants in the prophylaxis of depression. Adv. Biol Pyschiat., 7, 208–17.
Greenblatt, D.J., Divoli, M., Abernethy, D.R. and Shader, R.I. (1982) Physiologic change in old age: relation to altered drug disposition. J. Am. Geriat. Soc., 30, (Suppl.) S6–S10.
Hullin, R.P., McDonald, R. and Allsopp, M.N.E. (1972) Prophylactic lithium in recurrent affective disorders. Lancet, i, 1044–6.
Jerram, T.C. and McDonald, R. (1978) Plasma lithium control with particular reference to minimum effective levels. In: Lithium in Medical Practice (eds. F.N. Johnson and S. Johnson), MTP Press, Lancaster, pp. 407–13.
Kantor, S.J. and Glassman, A.H. (1980) In: Psychopharmacology of Ageing (eds. C. Eisdorfer and W.E. Fann), MTP Press, Lancaster, pp. 99–117.
Mindham, R.H.S., Howland, C. and Shepherd, M. (1973) An evaluation of continuation therapy with tricyclic antidepressants in depressive illness. Psychological Medicine, 3, 5–17.
Murphy, E. (1983) The prognosis of depression in old age. Br. J. Psychiat., 142, 111–13.
Perry, P.J. and Tsuang, M.T. (1979) Treatment of unipolar depression following electroconvulsive therapy: relapse rate comparisons between lithium and tricyclic therapies following ECT. J. Affect. Disord., 1, 123–9.
Prien, R.F., Klett, C.J. and Caffey, E.M. (1973) Lithium carbonate and Imipramine prevention of affective psychoses. Arch. Gen. Psychiat., 29, 303–13.
Quitkin, F., Rifkin, A. and Kane, J. (1978) Prophylactic effect of lithium and imipramine in unipolar and bipolar II patients: a preliminary report. Am. J. Psychiat., 133, 570–2.
Sashidhoran, B., McGuire, R.J. and Glen, A.I.M. (1982) Plasma lithium levels and therapeutic outcome in the prophylaxis of affective disorders: a retrospective study. Br. J. Psychiat., 140, 619–22.
Thompson, T.L., Moran, M.G. and Nies, A.S. (1983) Psychotropic drug use in the elderly (parts 1 and 2). N. Eng. J. Med., 308, 134–8; 194–9.
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Ghose, K., Coppen, A. (1989). Lithium in the prophylaxis of depressive illness in late life. In: Ghose, K. (eds) Antidepressants for Elderly People. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3436-9_7
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DOI: https://doi.org/10.1007/978-1-4899-3436-9_7
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