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Extranodal malignant lymphomas

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Biopsy Pathology of the Lymphoreticular System

Part of the book series: Biopsy Pathology Series ((BPS))

Abstract

Malignant lymphomas often involve sites that are not primary organs of the lymphoreticular system. This involvement may be part of a disseminated lymphomatous process and in such cases even when an extranodal tumour dominates the clinical presentation staging procedures will reveal lymphoma elsewhere. The organ distribution of disseminated lymphoma is rarely totally random but probably reflects the physiological circulation of the normal counterparts of the tumour cells; thus involvement of the jaws in Burkitt’s lymphoma is an age-dependent phenomenon (Wright, 1971) possibly related to dental development, and the remarkable involvement of the breasts in this disease during pregnancy and lactation (Shepherd and Wright, 1967) may be related to the physiological migration of B-lymphocytes to the breast at these times.

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Authors and Affiliations

  1. The University of Southampton, UK

    Dennis H. Wright B.Sc, M.D., F.R.C.Path. (Professor of Pathology, Honorary Consultant Pathologist) & Peter G. Isaacson D.M., M.R.C.Path. (Reader in Pathology, Honorary Consultant Pathologist, Now Professor of Morbid Anatomy)

  2. Southampton and South-West Hampshire District Health Authority, UK

    Dennis H. Wright B.Sc, M.D., F.R.C.Path. (Professor of Pathology, Honorary Consultant Pathologist) & Peter G. Isaacson D.M., M.R.C.Path. (Reader in Pathology, Honorary Consultant Pathologist, Now Professor of Morbid Anatomy)

  3. School of Medicine, University College, London, UK

    Peter G. Isaacson D.M., M.R.C.Path. (Reader in Pathology, Honorary Consultant Pathologist, Now Professor of Morbid Anatomy)

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  1. Dennis H. Wright B.Sc, M.D., F.R.C.Path.
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  2. Peter G. Isaacson D.M., M.R.C.Path.
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© 1983 D. H. Wright and P. G. Isaacson

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Wright, D.H., Isaacson, P.G. (1983). Extranodal malignant lymphomas. In: Biopsy Pathology of the Lymphoreticular System. Biopsy Pathology Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3396-6_13

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  • DOI: https://doi.org/10.1007/978-1-4899-3396-6_13

  • Publisher Name: Springer, Boston, MA

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