Skip to main content
SpringerLink
Log in
Book cover

Blood, Blood Products — and AIDS — pp 161–181Cite as

Blood donor screening for HIV infection: introduction in the United Kingdom and Europe and its impact on transfusion medicine

  • Chapter

  • 41 Accesses

Abstract

The preceding chapters have dealt with the nature of the immunological tests which are available to detect HIV infection, and describe the blood donor screening programmes operating in the United States. This chapter reflects the experience of the first year of routine HIV testing of blood donors in the United Kingdom and gives a view, necessarily very incomplete, of the situation in some other European countries.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Alter, H. J. (1986) Transmission of LAV/HTLV-III by blood products, in International Conference on AIDS, Paris, June 1986 (Program and Abstracts), p. 6, Communication SP10.

    Google Scholar 

  • Barclay, G. R., Hopcroft, W. and McClelland, D. B. L. (1986) What is an ‘equivocal’ negative HTLV-III antibody test in blood donors? Lancet, i, 912–13.

    Article  Google Scholar 

  • Böttiger, M. et al. (1986) Presentation at International Conference on AIDS, Paris, June 1986, Poster 662.

    Google Scholar 

  • Brettle, R. P., Davidson, J., Davidson, S. J., Gray, J. M. N., Inglis, J. M., Conn, J. S., Bath, G. E., Gillon, J. and McClelland, D. B. L. (1986) HTLV-III antibodies in an Edinburgh clinic. Lancet, i, 1099.

    Article  Google Scholar 

  • Caiazza, S. S. (1985) Alternative test sites for screening blood for antibodies to AIDS virus. N. Engl. J. Med., 313, 1158.

    Article  Google Scholar 

  • Carlson, J. R. et al. (1985) Lancet, i, 1388.

    Article  Google Scholar 

  • CDC (1986a) Human T-lymphotropic virus type Ill/lymphadenopathy-associated virus antibody testing at alternate sites. MMWR, 35, 284–7.

    Google Scholar 

  • CDC (1986b) Transfusion associated human T-lymphotropic virus type III/lym-phadenopathy-associated virus infection from a seronegative donor — Colorado. MMWR, 35, 389–91.

    Google Scholar 

  • CDC (1986c) Human T-lymphotropic virus type Ill/lymphadenopathy-associated virus antibody prevalence in U.S. Military recruit applicants. MMWR, 35, 421–4.

    Google Scholar 

  • Contreras, M., Hewitt, P. E., Barbara, J. A. and Mochnaty, P. Z. (1985) Blood donors at high risk of transmitting the acquired immune deficiency syndrome. Brit. Med. J., 290, 749–50.

    Article  CAS  Google Scholar 

  • Couroucé, A. M., Smilovici, W., North, M. L. and the Study Group of the French Society of Blood Transfusion (1986) Blood donors positive for anti-LAV antibodies in France: prevalence according to different criteria, in International Conference on AIDS, Paris, June 1986 (Program and Abstracts), p. 100, Communication 45.

    Google Scholar 

  • Coutinho, R. A. (1986) The natural history of LAV/HTLV-III infection, in International Conference on AIDS, Paris, June 1986 (Program and Abstracts), p. 99, Communication 37.

    Google Scholar 

  • Esteban, J. I., Wai-Kuo Shih, J., Tai, C. C., Bodner, A. J., Kay, J. W. D. and Alter, H. J. (1985) Importance of Western blot analysis in predicting infectivity of anti-HTLV-III/LAV positive blood. Lancet, ii, 1083–6.

    Article  Google Scholar 

  • Giachino, O. et al. (1986) Presentation at International Conference on AIDS, June 1986, Poster 389.

    Google Scholar 

  • Holland, P. V. et al. (1985) Transfusion, 25, 395–7

    Article  PubMed  CAS  Google Scholar 

  • Huisman, H. G., Winkel, I., Lelie, N., Tersmette, M., Goudsmit, J. and De Lange, J. (1986a) Comparison of three different immunoassays in their ability to establish in human sera the onset of IgG antibody response to LAV/HTLV-III infection, in International Conference on AIDS, Paris, June 1986 (Program and Abstracts), p. 145, Poster 635.

    Google Scholar 

  • Huisman, H. G., Winkel, I., Lelie, N., Tersmette, M., Goudsmit, J. and Miedema, F. (1986b) A LAV/HTLV-III radioimmuno-assay for confirmatory testing, in International Conference on AIDS, Paris, June 1986 (Program and Abstracts), p. 148, Poster 653.

    Google Scholar 

  • Jochen, A. B. B. et al. (1986) Presentation on International Conference on AIDS, June 1986, Poster 391.

    Google Scholar 

  • Kruskall, M. S. (1986) New trends in transfusion medicine: autologous transfusions and directed donations, in NIH Consensus Development Conference. Impact of Routine HTLV-III Antibody Testing of Blood and Plasma Donors on Public Health, Bethesda, July 1986 (Program and Abstracts), pp. 83–7.

    Google Scholar 

  • Kuhnl et al. (1986), Vox Sang, 51 (Suppl. 1), 15–20.

    Article  PubMed  Google Scholar 

  • Lange, J. M. A., Coutinho, R. A., Krone, W. J. A., Verdonck, L. F., Danner, S. A., Van der Noordaa, J. and Goudsmit, J. (1986) Distinct IgG recognition patterns during progression of subclinical and clinical infection with lymphadenopathy associated virus/human T lymphotropic virus. Brit. Med. J., 292, 228–30.

    Article  CAS  Google Scholar 

  • Ludlam, C. A., Steel, C. M., Cheinsong-Popov, R., McClelland, D. B. L., Tucker, J., Tedder, R. S., Weiss, R. A., Philp, I. and Prescott, R. J. (1985) Human T-lymphotropic virus type III (HTLV-III) infection in seronegative haemophiliacs after transfusion of factor VIII. Lancet, ii, 233–6.

    Article  Google Scholar 

  • Mercadier, A., Jullien, A. M., Guiard, J., Andreu, G., Noel, L., Couroucé, A. M. and the AIDS Study Group of the French National Blood Transfusion Society (1986) LAV/HTLV-III seropositivity among recipients of blood and blood components in Paris area, in International Conference on AIDS, Paris, June 1986 (Program and Abstracts), p. 102, Communication 58.

    Google Scholar 

  • Mortimer, P. T., Parry, J. V., Mortimer, J. Y. (1986) Which anti HTLV-III/LAV assays for screening and confirmatory testing? Lancet, ii, 873–7.

    Google Scholar 

  • NIH Consensus Development Conference (1986) Draft Consensus Statement: Impact of Routine HTLV-III Antibody Testing of Blood and Plasma Donors on Public Health, Bethesda, July 1986.

    Google Scholar 

  • O’Shaughnessy, M. V. et al. (1986) International Conference on AIDS, Abstract 417.

    Google Scholar 

  • Payne, B. C., Bishop, P., Rasheed, S., Gill, P., Levine, A. and Parker, J. W. (1986) The detection of HTLV-III/LAV associated surface antigens in human blood lymphocytes by flow cytometry, in International Conference on AIDS, Paris, June 1986 (Program and Abstracts) p. 144, Poster 633.

    Google Scholar 

  • Peutherer, J. F., Edmond, E., Simmonds, P., Dickson, J. D. and Bath, G. E. (1985) HTLV-III antibody in Edinburgh drug addicts. Lancet, ii, 1129–30.

    Article  Google Scholar 

  • Reesink, H. W. et al. (1986) International Conference on AIDS, Abstract 426.

    Google Scholar 

  • Rubin, C. P. et al. (1986) International Conference on AIDS, Abstract 420.

    Google Scholar 

  • Simmonds, P., Peutherer, J. F. and McClelland, D. B. L. (1986) HTLV-III/LAV antibody testing: confirmation methodologies and future prospects, in The Safety of Blood and Blood Products in Relation to AIDS. Proceedings of WHO Meeting, Geneva (ed. J. Petricciani), April 1986, to be published 1986.

    Google Scholar 

  • Ulstrup, J. C., Skaug, K., Figenschau, K. J., Ørstavik, I., Bruun, J. N. and Petersen, G. (1986) Sensitivity of Western blotting (compared with ELISA and immunofluorescence) during seroconversion after HTLV-III infection. Lancet, i, 1151–2.

    Article  Google Scholar 

Download references

Authors
  1. D. B. L. McClelland
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University Department of Medicine, Royal Infirmary, Glasgow, UK

    R. Madhok MD  & C. D. Forbes MD  & 

  2. Centers for Disease Control, Atlanta, USA

    B. L. Evatt MD

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

McClelland, D.B.L. (1987). Blood donor screening for HIV infection: introduction in the United Kingdom and Europe and its impact on transfusion medicine. In: Madhok, R., Forbes, C.D., Evatt, B.L. (eds) Blood, Blood Products — and AIDS —. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3394-2_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-3394-2_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-8018-3608-4

  • Online ISBN: 978-1-4899-3394-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation