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Donor screening for HIV in the United States

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Blood, Blood Products — and AIDS —

Abstract

As the first country to recognize AIDS, the United States was inevitably the first to develop and implement measures to reduce the transmission of the disease by blood transfusion. In essence, the problem has been attacked at three levels; first by the selection of low risk donor populations; secondly by use of laboratory test procedures and finally, by inactivating viruses in products derived from pooled plasma. The sensitive social issues associated with AIDS, along with the uniform fatality of the disease, generated numerous ethical, social and medical problems which had to be resolved during the development of the screening programmes. At the same time, laboratory tests for the identification of potentially infectious donors were developed, commercialized and implemented in a remarkably short time span. In fact, within two years of the initial recognition of the AIDS virus, donor testing was uniformly in place. It is reasonable to claim that these activities have prevented a significant number of cases of transfusion associated AIDS cases, as testing alone has identified several thousand infected and potentially infectious donors during its first year. Major milestones in the management of transfusion AIDS in the United States are outlined in Table 8.1. Even so, it must be remembered that only 2% of AIDS cases in the United States are due to transfusion and the major problems of this epidemic are yet to be solved.

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© 1987 Springer Science+Business Media Dordrecht

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Dodd, R.Y. (1987). Donor screening for HIV in the United States. In: Madhok, R., Forbes, C.D., Evatt, B.L. (eds) Blood, Blood Products — and AIDS —. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3394-2_8

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  • DOI: https://doi.org/10.1007/978-1-4899-3394-2_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-8018-3608-4

  • Online ISBN: 978-1-4899-3394-2

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