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Transfusion-associated AIDS

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Blood, Blood Products — and AIDS —

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Abstract

Soon after the epidemic of acquired immune deficiency syndrome (AIDS) began in the United States the preponderance of cases was found to be in two groups of individuals, homosexual men (CDC, 1981) and intravenous drug abusers (Wormser et al., 1983). This unusual distribution suggested hepatitis B as a possible model of transmission for proposed infectious agents. The occurrence of this syndrome in patients who had received blood products soon added additional support to that model. The Centers for Disease Control (CDC) received the first report of a haemophilia patient with Pneumocystis carinii pneumonia in January of 1982 and the second and third patients were found by the CDC through routine surveillance of requests in June and July of 1982 for drugs available only from CDC to treat P. carinii pneumonia (CDC, 1982a). Inquiries concerning these initial patients’ sexual activities, drug usage, ethnicity and travel or residence provided little evidence that the disease could have been acquired by contact with homosexuals, illicit drug abusers or Haitian immigrants. The hypothesis that AIDS developed in these patients as a result of an infectious agent transmitted by the blood products’ administration seemed logical and research for the occurrence of disease in transfusion recipients intensified. Soon it became clear that AIDS was a major problem for blood banks and the plasma industry.

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Authors
  1. Terence L. Chorba
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  2. Bruce L. Evatt
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Editors and Affiliations

  1. University Department of Medicine, Royal Infirmary, Glasgow, UK

    R. Madhok MD  & C. D. Forbes MD  & 

  2. Centers for Disease Control, Atlanta, USA

    B. L. Evatt MD

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Chorba, T.L., Evatt, B.L. (1987). Transfusion-associated AIDS. In: Madhok, R., Forbes, C.D., Evatt, B.L. (eds) Blood, Blood Products — and AIDS —. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3394-2_2

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  • DOI: https://doi.org/10.1007/978-1-4899-3394-2_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-8018-3608-4

  • Online ISBN: 978-1-4899-3394-2

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