Abstract
The adrenal glands are paired retroperitoneal organs lying superomedial to each kidney. Each adrenal gland consists of an outer cortex and an embryologically, histologically and functionally distinct medulla. The cortex is derived from the posterior coelomic mesoderm (the urogenital ridge). It is responsible for the synthesis of glucocorticoids (principally Cortisol), mineralocor-ticoids (principally aldosterone) and weak androgens (dehydroepiandrosterone (DHEA), its sulphate (DHEA-S) and androstenedione). The adrenal medulla shares its origin from the neural crest with the sympathetic ganglia and paraganglia and other adrenergic tissues. Like those organs, it synthesizes and stores noradrenaline, but it is unique in its ability to convert noradrenaline to adrenaline.
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Khafagi, F.A., Shapiro, B., Gross, M.D. (1991). The adrenal gland. In: Maisey, M.N., Britton, K.E., Gilday, D.L. (eds) Clinical Nuclear Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3358-4_11
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DOI: https://doi.org/10.1007/978-1-4899-3358-4_11
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