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Techniques and experiments illustrating drug metabolism

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Abstract

This chapter is designed to illustrate experimentally some of the concepts discussed in this book. The experiments described herein are derived from undergraduate practicals that have been running in the authors’ laboratories for several years. The design of adequate experiments illustrating drug metabolism is not an easy task. For example, practical classes can suffer from time constraints in that the experiments usually have to be completed in one day. In addition, experimental design must also take account of practical constraints such as availability of reagents or analytical instrumentation. Accordingly, we have described a series of experiments that are flexible and can be tailored to suit either the size of a practical class, the time available or access to specific instrumentation.

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© 1986 G. G. Gibson and P. Skett

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Gibson, G.G., Skett, P. (1986). Techniques and experiments illustrating drug metabolism. In: Introduction to Drug Metabolism. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3188-7_8

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  • DOI: https://doi.org/10.1007/978-1-4899-3188-7_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-26390-3

  • Online ISBN: 978-1-4899-3188-7

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